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A kind of formula granule, preparation method and detection method thereof

A technology of Artemisia zebrascens and formula granules, which is applied in the field of medicine, can solve the problems of unguaranteed drug safety and troublesome decoction methods, and achieve the effects of difficult storage, safe drug use, and moderate Rf value

Active Publication Date: 2021-10-01
国药普兰特(青海)药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The traditional decoction method of Artemisia zebrae decoction pieces is extremely troublesome. Patients do not know much about the amount of water added, soaking time, heat, decoction time, decoction first, and second, etc., resulting in not decocting as required, which leads to Medication safety is not guaranteed

Method used

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  • A kind of formula granule, preparation method and detection method thereof
  • A kind of formula granule, preparation method and detection method thereof
  • A kind of formula granule, preparation method and detection method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Example 1 Artemisia zebrascens dry paste powder 200g, silicon dioxide 0.5g, sodium lauryl sulfate 1g.

Embodiment 2

[0062] Example 2 Artemisia zebrascens dry paste powder 300g, silicon dioxide 1g, sodium lauryl sulfate 2g.

Embodiment 3

[0063] Example 3 Artemisia zebrascens dry paste powder 250g, silicon dioxide 0.8g, sodium lauryl sulfate 1.5g.

[0064] The formulations of Examples 1-3 are made according to any one of the preparation methods of Examples 4-6, and tested according to any of the detection methods of Examples 7-12 after being made.

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Abstract

The invention relates to a formula granule of Artemisia zebrae, a preparation method and a detection method thereof. The formula granule is composed of dry paste powder of Artemisia zebrae, silicon dioxide and sodium lauryl sulfate. The present invention is obtained by extracting, spray-drying and granulating the single herbal medicine of Artemisia zebrais, which is convenient for doctors to carry out syndrome differentiation and treatment, and can be added or subtracted according to the syndrome; Chromatographic identification, using high-performance liquid chromatography to determine the content of its main component luteolin, and using the UV-Visible spectrophotometric method to measure the content of luteolin with the reference substance of luteolin as a comparison, can fully reflect the quality of the zebra liped horse Xianhao formula granules, It is ensured that the active ingredients are fully retained and the content is stable, so that the drug quality detection method is more scientific and perfect, and the drug quality is better controlled.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a preparation method and a quality detection method of zebra liped Artemisia formula granules. Background technique [0002] Pedicularis longiflora Rudolph.var.tubiformis [0003] (Klotz.) Tsoong, Scrophulariaceae Artemisia genus marsh herb, belonging to the plant kingdom, widely distributed in Tibet, mostly distributed in alpine meadows, swamps, forest edge wetlands at an altitude of 2700-5300m, northwest Yunnan, western Sichuan and along the Himalayas Also produced in various countries, 5-20cm high, leaves lanceolate to narrowly lanceolate, pinnately parted to completely divided. The flowers are axillary, the corolla is yellow, with a 6mm long beak, and 2 brown-red or purple-brown stains on the throat. The flowering period is from May to October. [0004] Artemisia zebrais has high medicinal value, such as clearing heat and detoxifying, strengthening tendons and diuresis, strengtheni...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/80A61K9/16A61K47/04A61K47/20G01N30/02G01N30/06G01N30/54G01N30/74G01N30/90G01N30/94
CPCA61K9/1611A61K9/1617A61K36/80A61K2236/331A61K2236/51G01N30/02G01N30/06G01N30/54G01N30/74G01N30/90G01N30/94G01N2030/027G01N2030/062
Inventor 王飞郭静陈钟余梅李生萍
Owner 国药普兰特(青海)药业有限公司