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Pedicularis longiflora Rudolph.var.tubiformis formula granule, preparation method and detection method thereof

A technology of Artemisia annua and formula granules, applied in the field of medicine, can solve the problems of troublesome decoction method, unguaranteed medication safety and the like

Active Publication Date: 2019-08-02
青海普兰特药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The traditional decoction method of Artemisia zebrae decoction pieces is extremely troublesome. Patients do not know much about the amount of water added, soaking time, heat, decoction time, decoction first, and second, etc., resulting in not decocting as required, which leads to Medication safety is not guaranteed

Method used

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  • Pedicularis longiflora Rudolph.var.tubiformis formula granule, preparation method and detection method thereof
  • Pedicularis longiflora Rudolph.var.tubiformis formula granule, preparation method and detection method thereof
  • Pedicularis longiflora Rudolph.var.tubiformis formula granule, preparation method and detection method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Example 1 Artemisia zebrascens dry paste powder 200g, silicon dioxide 0.5g, sodium lauryl sulfate 1g.

Embodiment 2

[0062] Example 2 Artemisia zebrascens dry paste powder 300g, silicon dioxide 1g, sodium lauryl sulfate 2g.

Embodiment 3

[0063] Example 3 Artemisia zebrascens dry paste powder 250g, silicon dioxide 0.8g, sodium lauryl sulfate 1.5g.

[0064] The formulations of Examples 1-3 are made according to any one of the preparation methods of Examples 4-6, and tested according to any of the detection methods of Examples 7-12 after being made.

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Abstract

The invention relates to a pedicularis longiflora Rudolph.var.tubiformis formula granule, a preparation method and a detection method thereof. The formula granule is composed of pedicularis longifloraRudolph.var.tubiformis dry paste powder, silicon dioxide and sodium lauryl sulfate. The formula granule is prepared by performing digestion, spray drying and pelletizing on a single drug of the pedicularis longiflora Rudolph.var.tubiformis, and is convenient for a physician to carry out treatment based on syndrome differentiation and add and reduce according to syndromes; the detection method ofthe pedicularis longiflora Rudolph.var.tubiformis formula granule comprises performing thin layer chromatography identification by using a reference crude herb of the pedicularis longiflora Rudolph.var.tubiformis and a reference substance of luteolin, measuring the content of the main component luteolin by using high performance liquid chromatography, and detecting the content of tricin by using ultraviolet-visible spectrophotometry with the reference substance of the tricin as control; the detection method can reflect the quality of the pedicularis longiflora Rudolph.var.tubiformis formula granule comprehensively, guarantees complete reservation and stable content of the active ingredients of the pedicularis longiflora Rudolph.var.tubiformis formula granule, and makes the detection methodof the medicine quality more scientific and complete, and the medicine quality is better controlled.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a preparation method and a quality detection method of zebra liped Artemisia formula granules. Background technique [0002] Pedicularis longiflora Rudolph.var.tubiformis [0003] (Klotz.) Tsoong, Scrophulariaceae Artemisia genus marsh herb, belonging to the plant kingdom, widely distributed in Tibet, mostly distributed in alpine meadows, swamps, forest edge wetlands at an altitude of 2700-5300m, northwest Yunnan, western Sichuan and along the Himalayas Also produced in various countries, 5-20cm high, leaves lanceolate to narrowly lanceolate, pinnately parted to completely divided. The flowers are axillary, the corolla is yellow, with a 6mm long beak, and 2 brown-red or purple-brown stains on the throat. The flowering period is from May to October. [0004] Artemisia zebrais has high medicinal value, such as clearing heat and detoxifying, strengthening tendons and diuresis, strengtheni...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/80A61K9/16A61K47/04A61K47/20G01N30/02G01N30/06G01N30/54G01N30/74G01N30/90G01N30/94
CPCA61K9/1611A61K9/1617A61K36/80A61K2236/331A61K2236/51G01N30/02G01N30/06G01N30/54G01N30/74G01N30/90G01N30/94G01N2030/027G01N2030/062
Inventor 王飞郭静陈钟余梅李生萍
Owner 青海普兰特药业有限公司
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