Intensity modulated radiation therapy plan three-dimensional dose distribution prediction method based on deep network learning

Abstract

The invention provides an intensity modulated radiation therapy plan three-dimensional dose distribution prediction method based on deep learning. The intensity modulated radiation therapy plan three-dimensional dose distribution prediction method comprises the following steps: collecting effective intensity modulated radiation therapy plan data to form a case database; extracting three-dimensional anatomical structure contour features of the region of interest of each patient from the case database; dividing the three-dimensional anatomical structure contour of the region of interest of the patient into a plurality of two-dimensional contour slice graphs; extracting dose features of each patient from the case database, and dividing the dose features into a plurality of two-dimensional dose slice distribution graphs; establishing a deep convolutional network, inputting the two-dimensional contour slice graph and the corresponding two-dimensional dose slice distribution graph of the patient, and obtaining an association model between anatomical structure contour features and dose features through model training; and predicting the three-dimensional dose distribution of the new patient by using the trained association model. By means of the intensity modulated radiation therapy plan three-dimensional dose distribution prediction method, the incidence relation between the anatomical structure features and the dose features can be effectively obtained, and the accuracy of dose prediction is improved.

Description

technical field [0001] The invention relates to the technical field of intelligent radiotherapy, in particular to a method for predicting three-dimensional dose distribution in an intensity-modulated radiotherapy plan based on deep network learning. Background technique [0002] Tumor radiotherapy, with its unique advantages, has become one of the main means of tumor treatment proposed by the World Health Organization. Its main goal is to reduce the dose deposition of surrounding normal tissues as much as possible while ensuring that the target area can reach a specific dose. Improve the local control rate of tumor. Intensity-modulated radiation therapy, namely intensity-modulated conformal radiation therapy, is a kind of three-dimensional conformal radiation therapy, which requires the dose intensity in the radiation field to be adjusted according to certain requirements. It makes the distribution of radiotherapy dose consistent with the shape of the target area, and the t...

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Problems solved by technology

[0007] The purpose of the present invention is to overcome the defects of the above-mentioned prior art, and provide a three-dimensional dose distribution prediction method suitable for intensity-modulated

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