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Tumor radiotherapy medicine capable of lowering damage of RE (radiation esophagitis) to patient and preparation method thereof

A tumor radiotherapy and patient technology, applied in the field of clinical nursing, can solve the problems of intermittent duration, lower RE level, and influence on treatment efficacy, and achieve the effects of avoiding the occurrence of RE, shortening the time of RE, and delaying the time of RE

Inactive Publication Date: 2019-09-06
陶鹤
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] To sum up, the problems existing in the existing technology are: patients appear at the end of radiotherapy or just after the end of radiotherapy, and most patients choose to be discharged from the hospital due to the end of treatment, or some RE patients appear during treatment and still have symptoms after treatment
[0011] For patients with chest tumors who expect to receive radiation therapy, after oral administration of sodium bicarbonate-based oral liquid, the occurrence time of RE is delayed, the duration is intermittent, and the level of RE is reduced. Patients can not interrupt treatment because of the occurrence of RE, which will affect the curative effect of treatment

Method used

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  • Tumor radiotherapy medicine capable of lowering damage of RE (radiation esophagitis) to patient and preparation method thereof
  • Tumor radiotherapy medicine capable of lowering damage of RE (radiation esophagitis) to patient and preparation method thereof

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Effect test

preparation example Construction

[0028] Such as figure 1 Shown, the preparation method of the medicine that reduces RE that the embodiment of the present invention provides and damages the tumor radiotherapy of patient comprises:

[0029] S101: Prepare 500ml of 0.9% normal saline, 20ml of sodium bicarbonate injection, 20ml of lidocaine injection, 160,000 units of gentamicin and 5mg of dexamethasone phospholipid sodium injection;

[0030] S102: Mix 500 ml of 0.9% normal saline, 20 ml of sodium bicarbonate injection, 20 ml of lidocaine injection, 160,000 units of gentamicin and 5 mg of dexamethasone phospholipid sodium injection.

[0031] The method of taking the drug for reducing RE damage to tumor radiotherapy provided by the embodiment of the present invention is as follows: take orally 4 times a day, 50ml each time, and put it in the mouth to make the liquid flow down by itself.

Embodiment

[0036] 1. The enrolled patients were randomly divided into a treatment group and a control group, with 45 patients in each group. The treatment group began to take oral liquid based on sodium bicarbonate (main formula ingredients: 0.9% normal saline 500ml, sodium bicarbonate injection 20ml, lidocaine injection 20ml, gentamicin 16 mg) 1 week after radiotherapy. 10,000 units, dexamethasone phospholipid sodium injection 5mg), usage: take orally 4 times a day, 50ml each time, contain it in the mouth to make the liquid flow down by itself, the purpose is to make the liquid fully contact with the esophageal mucosa. The patients in the control group only received radiation therapy, without any intervention of drugs that may affect the experiment. The clinical record of each patient's treatment, prescription dose, time, grade and duration of RE.

[0037] 2. Carry out continuous nursing care for patients with RE after they are discharged from the hospital, register as nursing, and rec...

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Abstract

The invention belongs to the technical field of clinical nursing and discloses tumor radiotherapy medicine capable of lowering damage of RE (radiation esophagitis) to a patient and a preparation method thereof. The medicine comprises 500ml of 0.9% normal saline, 20ml of sodium bicarbonate injection, 20ml of lidocaine injection, 160000 unit of gentamicin and 5mg of dexamethasone sodium phosphate injection. The tumor radiotherapy medicine has the advantages that the self-made oral liquid using sodium bicarbonate as the main raw material is used to delay the RE occurrence time of the patient, reduce RE level, shorten RE time or avoid RE so as to allow the treatment of the patient to be completed smoothly; the continuing nursing care is used to guide the self-nursing of the patient who leavesthe hospital, guide the patient to continuously follow the original diet principle, pay attention to self-monitoring and regularly have reexamination in the hospital to conveniently obtained further health promotion.

Description

technical field [0001] The invention belongs to the technical field of clinical nursing, and in particular relates to a drug and a preparation method for reducing RE damage to tumor radiotherapy for patients. Background technique [0002] Currently, the closest prior art: [0003] Radiation esophagitis (RE) refers to the aseptic inflammatory reaction caused by hyperemia, edema, degeneration and necrosis of mucosal epithelial cells in the normal esophagus in the irradiation field after irradiation. The esophagus is an important dose-limiting organ in thoracic radiotherapy. When the dose reaches 10-20 Gy, the normal esophageal mucosa in the irradiation field may experience hyperemia, edema, and dysphagia; Burning sensation behind the breastbone, especially when eating. Severe esophagitis may require interruption of radiotherapy and hospitalization for symptomatic treatment, which seriously affects the quality of life of patients, the efficacy of treatment, and negatively aff...

Claims

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Application Information

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IPC IPC(8): A61K33/00A61P1/00A61K31/167A61K31/7036A61K31/573
CPCA61K9/0095A61K31/167A61K31/573A61K31/7036A61K33/00A61P1/00A61K2300/00
Inventor 陶鹤敬谢攀张宏毅孙正秀李华清蒲金川彭玲宋雄军巴德·玛拉
Owner 陶鹤
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