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A self-positioning actuator for magnetic chromatography chips

A transmission device and magnetic layer technology, which is applied in the field of self-positioning transmission device, can solve the problems of being easily affected by the operator's experience, inaccurate measurement results, and troublesome processing of the detection device, so as to shorten the detection time and improve the structural stability , the effect of easy processing

Active Publication Date: 2021-07-13
SHANGHAI JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] In view of the above-mentioned defects of the prior art, the technical problem to be solved by the present invention is that the chip clamp in the prior art cannot make the chip and the sensor reach the optimal detection distance; it is necessary to manually locate the detection on the magnetic chromatography chip through multiple measurements. The position of the line and the quality control line relative to the detection coil, the operation process is cumbersome, time-consuming, and is easily affected by the experience of the operator, and the measurement results obtained are not accurate enough; the processing of the existing detection device is cumbersome, heavy and energy-consuming

Method used

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  • A self-positioning actuator for magnetic chromatography chips
  • A self-positioning actuator for magnetic chromatography chips
  • A self-positioning actuator for magnetic chromatography chips

Examples

Experimental program
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Effect test

Embodiment 1

[0037] Such as figure 1 As shown, this embodiment provides a self-positioning transmission device for a magnetic chromatography chip, including a chip holder 4, a worktable, a driving mechanism, and a position detection mechanism.

[0038] Such as Figure 4 As shown, the chip clip 4 is a cuboid plate-shaped member, and the upper surface of the chip clip 4 is provided with a chip clamping position, a drip hole, a two-dimensional code sticking area 22, and an anti-skid pattern 16. The chip clamping position is used to clamp the chip. The drip hole is located on the right side of the upper surface of the chip holder 4, the two-dimensional code sticking area 22 is located on the left side of the upper surface of the chip holder 4, and the anti-slip texture 16 is located outside the middle of the upper surface of the chip holder 4; the left end surface of the chip holder 4 and The right end faces are parallel to each other, chamfers are provided under the left end face and the rig...

Embodiment 2

[0050] On the basis of Embodiment 1, the transmission mechanism is replaced to include a lead screw, a lead screw nut, and a lead screw support column. The stepper motor 12 is fixedly installed on the installation frame 19, and the number of lead screw support columns is 2, which are fixedly arranged respectively. On both sides of the moving track of the chip holder tray, the lead screw passes through the lead screw support column and is fixedly connected with the output shaft of the stepping motor 12. The lead screw and the lead screw support column form a rotating pair, and the lead screw nut and the lead screw form a ball screw transmission. , the lead screw nut is fixedly connected with the chip holder tray, and the central axis of the lead screw is parallel to the sliding track of the chip holder tray.

[0051] The grating is replaced by an absolute value rotary encoder, which is set to detect the rotational angular displacement of the lead screw.

Embodiment 3

[0053] On the basis of Embodiment 2, the stepper motor 12 is replaced by a servo motor, and a reducer is arranged between the servo motor and the lead screw.

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Abstract

The invention discloses a self-positioning transmission device for a magnetic chromatography chip, relates to the technical field of detection devices, and includes a chip clamp, a workbench, a driving mechanism, and a position detection mechanism. The chip clamp is a plate-shaped member, and the working The table includes an upper bracket, a lower bracket, and a chip holder tray, the upper bracket is fixedly installed directly above the lower bracket, the chip holder tray is slidably arranged between the upper bracket and the lower bracket, and the chip The clip tray is provided with a chute matching the left and right end faces of the chip clip; the drive mechanism includes a power source, a transmission mechanism, and a mounting frame; the position detection mechanism includes a detection element and a detection mounting bracket. The invention can realize the automatic positioning of the magnetic chromatography chip, simplifies the operation process, improves the accuracy of the measurement result, and has the advantages of simple processing and light structure.

Description

technical field [0001] The invention relates to the technical field of detection devices, in particular to a self-positioning transmission device for a magnetic chromatography chip. Background technique [0002] Immunoassay technology uses nanoparticles as markers to detect the analyte. Immunochromatography technology combines chromatography technology with immune technology, that is, the combination of immunological reaction process and chromatographic physical process. In this way, a new rapid detection technology has been developed, which has the same advantages as traditional immunoassay technology in terms of detection specificity and sensitivity. [0003] Immunochromatographic detection is mainly done with the help of immunochromatographic chips. The immunochromatography chip is composed of four parts, including nitrocellulose membrane, binding pad, sample pad and absorption pad. The nitrocellulose membrane is used as the chromatography and detection carrier and is th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/558G01N33/543G01B11/00
CPCG01B11/00G01N33/5302G01N33/54326G01N33/54346G01N33/558
Inventor 王侃曹勃徐昊
Owner SHANGHAI JIAOTONG UNIV