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Hydrophobic low-eutectic-point solvent based on lidocaine and preparation method and extraction application of solvent

A technology of low eutectic solvent and lidocaine, which is applied in liquid solution solvent extraction, imino compound preparation, organic chemistry and other directions, can solve problems such as no discovery, and achieve the effects of stable performance, excellent extraction performance and simple synthesis

Active Publication Date: 2019-09-24
HENAN NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] So far, we have not found that n-octyl p-hydroxybenzoate is used as a hydrogen bond donor, and lidocaine is a hydrophobic deep eutectic solvent synthesized by a hydrogen bond acceptor and used for rhodamine B and rhodamine B. Reports on separation and enrichment of other large cations

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Weigh lidocaine and n-octyl p-hydroxybenzoate respectively according to the molar ratio of 1:0.25~3, then put the mixture in a round bottom flask, stir for 0.25~4h under the heating condition of 40~80℃ to form uniform clarification Transparent liquid, i.e. hydrophobic deep eutectic solvent.

Embodiment 2

[0027] Weigh a certain amount of the hydrophobic deep eutectic solvent synthesized in Example 1 respectively in a certain amount of Rhodamine B aqueous solution whose concentration is 10 mg / L. Under the condition of not adjusting the pH value of the solution, the content of rhodamine B in the aqueous phase was determined after vortex centrifugation. According to the measurement result, it can be known that the hydrophobic deep eutectic solvents of all different mol ratios prepared have an extraction effect on rhodamine B, and when the mol ratio of lidocaine and n-octyl p-hydroxybenzoate in the hydrophobic deep eutectic solvent is When the ratio is 1:2, the extraction rate of Rhodamine B in Rhodamine B aqueous solution is as high as 99%.

Embodiment 3

[0029] Weigh a certain amount of the hydrophobic deep eutectic solvent synthesized in Example 1 respectively in a certain amount of methyl violet aqueous solution with a concentration of 10 mg / L. Under the condition of not adjusting the pH value of the solution, the content of methyl violet in the aqueous phase was determined after vortex centrifugation. According to the measurement result, it can be known that the hydrophobic deep eutectic solvents of all different mol ratios prepared have an extraction effect on methyl violet, and when the mol ratio of lidocaine and n-octyl p-hydroxybenzoate in the hydrophobic deep eutectic solvent is When the ratio is 1:1, the extraction rate of methyl violet in the methyl violet aqueous solution is as high as 97%.

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Abstract

The invention discloses a hydrophobic low-eutectic-point solvent based on lidocaine and a preparation method and extraction application of the solvent, and belongs to the technical field of extraction, separation and enrichment of large cationic compounds. The hydrophobic low-eutectic-point solvent based on lidocaine is characterized in that the hydrophobic low-eutectic-point solvent is synthesized from lidocaine serving as a hydrogen bond acceptor and n-octyl p-hydroxybenzoate serving as a hydrogen bond donor in the molar ratio of 1:(0.25-3). The invention particularly discloses the preparation method of the hydrophobic low-eutectic-point solvent based on lidocaine and application of the solvent in extraction of rhodamine B, methyl violet or / and malachite green in an aqueous solution. When used as an extraction agent, the prepared hydrophobic low-eutectic-point solvent has the advantages of being easy to synthesize, stable in performance, low in toxicity, high in extraction efficiency and the like.

Description

technical field [0001] The invention belongs to the technical field of extraction, separation and enrichment of large cationic compounds, and in particular relates to a lidocaine-based hydrophobic deep eutectic solvent, a preparation method thereof, and an extraction application. Background technique [0002] A deep eutectic solvent usually refers to a mixture of two or more substances formed by hydrogen bonding, whose melting point is lower than that of each component and which is liquid at room temperature. Deep eutectic solvent is a new type of green solvent. It not only has the advantages of low vapor pressure of ionic liquid, good electrical and thermal conductivity, low melting point, wide liquid range, and strong thermal stability, but also has the advantages of low price, simple preparation, and no need for Further purification and other advantages. Due to its superior physical and chemical properties, deep eutectic solvents have been used in electrochemical reactio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01D11/04C07D311/84C07C249/02C07C251/30
CPCB01D11/04C07C249/02C07D311/84C07C251/30
Inventor 樊静时悦悦吴甜杨西通杜萌萌李铁梅朱文娟靳平宁师东阳付元奇
Owner HENAN NORMAL UNIV
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