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Natural polysaccharide and application in preparation of cosmetics for promoting skin repair and improving skin elasticity

A natural source polysaccharide technology, which is applied in the field of improving skin elasticity to prepare cosmetics, natural source polysaccharides and promoting skin repair, can solve the problems of waste of resources and low utilization, and achieve the promotion of skin repair, proliferation and migration, and improvement The effect of skin elasticity

Active Publication Date: 2019-11-05
美健极生物工程技术(广州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Butterbur is a very common perennial herb, but its utilization is extremely low, resulting in a great waste of resources

Method used

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  • Natural polysaccharide and application in preparation of cosmetics for promoting skin repair and improving skin elasticity
  • Natural polysaccharide and application in preparation of cosmetics for promoting skin repair and improving skin elasticity
  • Natural polysaccharide and application in preparation of cosmetics for promoting skin repair and improving skin elasticity

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Experimental program
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Effect test

Embodiment Construction

[0022] 1. Experimental method

[0023] 1. Preparation of polysaccharides

[0024] Grind the dried whole herb of Butterbur, add absolute ethanol according to the ratio of material to liquid 1:5 (kg:L) and extract under reflux for 3 hours to degrease, repeat the degreasing once, filter, and filter the residue according to the ratio of material to liquid 1:10 (kg:L) L) Add distilled water, heat and extract at 85°C for 12 hours, filter, collect the filtrate, concentrate the filtrate to extract under reduced pressure, add distilled water according to the ratio of material to liquid 1:5 (kg:L), stir to fully dissolve, filter with suction, and add the filtrate 4 times the volume of absolute ethanol, stirred evenly, ethanol precipitation for 12 hours, centrifuged, discarded the supernatant, washed with acetone and absolute ethanol in turn, dissolved with an appropriate amount of distilled water, and freeze-dried to obtain butterbur polysaccharide.

[0025] 2. Human skin fibroblast cu...

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Abstract

The invention discloses a natural polysaccharide and application in preparation of cosmetics for promoting skin repair and improving skin elasticity. A preparation method of the polysaccharide comprises the following steps: crushing dried whole herb of petasites japonicus, adding absolute ethyl alcohol, carrying out hot reflux extraction, degreasing and filtering, adding distilled water into filter residues, carrying out heating extraction and filtering, collecting filtrate, carrying out reduced pressure concentration on the filtrate to obtain an extract, adding a proper amount of distilled water, executing stirring to make the extract fully dissolved, carrying out suction filtration, adding absolute ethyl alcohol 4 times by volume of the filtrate into the filtrate, executing even stirring, alcohol precipitation and centrifugation, discarding supernatant, executing washing sequentially with acetone and absolute ethyl alcohol, dissolving the product with a proper amount of distilled water, and carrying out freeze drying. The polysaccharide can promote proliferation and migration of human skin fibroblasts, has the effect of promoting skin repair, can promote human skin fibroblasts toproduce collagen and elastin, has the effect of improving skin elasticity, and can be used for preparing cosmetics for promoting skin repair and improving skin elasticity.

Description

technical field [0001] The invention belongs to the field of cosmetics and relates to the use of polysaccharides from natural sources in cosmetics, in particular to the use of polysaccharides from natural sources to promote skin repair and improve skin elasticity to prepare cosmetics. Background technique [0002] It is human nature to love beauty, but with age, people's skin repair ability and skin elasticity will decline. [0003] Human skin repair ability mainly depends on the proliferation speed and migration ability of human skin fibroblasts. As people age, the decline in proliferation speed and migration ability of skin fibroblasts is the direct cause of the decline in skin repair ability. [0004] The elasticity of human skin is mainly related to the content of collagen and elastin. Collagen and elastin are composed of collagen fibers and elastic fibers respectively. Collagen fibers mainly support volume, maintain moisture, and make the skin plump. Elastic fibers mai...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08B37/00A61K8/73A61Q19/08A61Q19/00
CPCA61K8/73A61K2800/84A61Q19/00A61Q19/08C08B37/00C08B37/0003
Inventor 洪其昌
Owner 美健极生物工程技术(广州)有限公司
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