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A method for preparing medical ultrasonic couplant sterile product that can be used safely

An ultrasonic couplant and sterile product technology, applied in echo/ultrasonic imaging agent, heating, disinfection and other directions, can solve the problems of difficult product sterility assurance, high production cost, high operating cost, and achieve stable product chemical composition, The effect of low production cost and simple operation

Active Publication Date: 2020-06-12
广州广工技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The aseptic packaging machine is strictly sterilized, the process is complex, and the operation cost is high. The price of the entire packaging machine is as high as several million yuan. A large amount of sterilized preparations are consumed during packaging, which requires an aseptic production site. The production cost is high, and the product is non-toxic. Bacterial quality is not easy to guarantee

Method used

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  • A method for preparing medical ultrasonic couplant sterile product that can be used safely
  • A method for preparing medical ultrasonic couplant sterile product that can be used safely
  • A method for preparing medical ultrasonic couplant sterile product that can be used safely

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] First prepare medical ultrasonic coupling agent, dissolve the water-soluble polymer compound carbomer thickener with pure water, add triethanolamine to neutralize the solution until the pH value of the solution is 6.5-7.2, then add humectant propylene glycol and glycerin, and stir evenly After that, the air bubbles are removed by vacuum to become a medical ultrasonic coupling agent.

[0028] Its preparation formula is as follows:

[0029]

[0030]

[0031] Methods for preparing medical ultrasonic coupling agent sterile products that can be safely used:

[0032] S1. Take 20 kg of unsterilized medical ultrasonic coupling agent, put it in a 25-liter stainless steel bucket with a cover, and put it in a steam sterilization device with a pressure of 0.14Mpa to 0.22Mpa for sterilization; use steam to heat, set the heating The temperature is 121°C, and the sterilization time is maintained for 20 minutes. The indicator of the sterilization chemical indicator card reaches or...

Embodiment 2

[0037] First prepare medical ultrasonic coupling agent, dissolve the water-soluble polymer compound carbomer thickener with pure water, add triethanolamine to neutralize the solution until the pH value of the solution is 6.5-7.2, then add humectant propylene glycol and glycerin, and stir evenly After that, the air bubbles are removed by vacuum to become a medical ultrasonic coupling agent.

[0038] The preparation formula of medical ultrasonic coupling agent is as follows:

[0039]

[0040] Methods for preparing medical ultrasonic coupling agent sterile products that can be safely used:

[0041] S1. Take 20 kg of unsterilized medical ultrasonic coupling agent, put it in a 25-liter stainless steel bucket with a cover, and put it in a steam sterilization device with a pressure of 0.14Mpa to 0.22Mpa for sterilization; use steam to heat, set the heating The temperature is 134°C, and the sterilization time is maintained for 20 minutes. The indicator of the sterilization chemica...

Embodiment 3

[0045] First prepare medical ultrasonic coupling agent, dissolve the water-soluble polymer compound carbomer thickener with pure water, add triethanolamine to neutralize the solution until the pH value of the solution is 6.5-7.2, then add humectant propylene glycol and glycerin, and stir evenly After that, the air bubbles are removed by vacuum to become a medical ultrasonic coupling agent.

[0046] Its preparation formula is as follows:

[0047]

[0048] Methods for preparing medical ultrasonic coupling agent sterile products that can be safely used:

[0049] S1. Take 20 kg of unsterilized medical ultrasonic coupling agent, put it in a 25-liter stainless steel bucket with a cover, and put it in a steam sterilization device with a pressure of 0.14Mpa to 0.22Mpa for sterilization; use steam to heat, set the heating The temperature is 134°C, and the sterilization time is maintained for 20 minutes. The indicator of the sterilization chemical indicator card reaches or is deeper...

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Abstract

The invention discloses a safe use method for preparing a medical ultrasonic coupling agent sterile product, wherein the method comprises the following steps: S1, putting an unsterilized medical ultrasonic coupling agent material into a stainless steel barrel, and carrying out steam sterilization, wherein the formula of the medical ultrasonic coupling agent material comprises 0.5-1.5% of carbomer,3-5% of propylene glycol, 1-3% of glycerol, 1-2% of triethanolamine, and the balance being purified water; S2, after sterilization, cooling the medical ultrasonic coupling agent material to 25 DEG C-80 DEG C, and packaging, wherein a packaging bag is an aluminum composite film packaging bag, the aluminum composite film packaging bag is of a four-layer film structure, and four layers of films sequentially comprise a polyester layer, an aluminum foil layer, a polyamide or Kevlar layer and a polyethylene or polypropylene layer from outside to inside; and S3, after packaging is completed, carrying out terminal thermal sterilization. For facilitating the use of an operating table, a layer of specially-made paper-plastic bag is sleeved on an aluminum composite film packaging bag of a common sterile product, and then sterilization is carried out again. Compared with other methods, the safe use method is simple to operate, good in product quality and low in production cost.

Description

technical field [0001] The invention relates to the field of sterilization of medical ultrasonic couplants, in particular to a thermal sterilization method for preparing medical ultrasonic couplant sterile products which can be safely used. Background technique [0002] The medical ultrasonic coupling agent is a gel-like preparation used in the human body for ultrasonic examination. Its purpose is to eliminate the air between the ultrasonic probe and the examined part of the human body, strengthen the coupling between the ultrasonic probe and the examined part, and make the sound wave transmission not affected by the air. Attenuation of the influence of the test results to obtain reliable test results and provide a basis for doctors to make a correct diagnosis. At present, the ultrasonic transmission medium used in intracavitary and puncture operations must use medical ultrasonic coupling agent sterile products, which can avoid bacterial infection during diagnosis and operat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K49/22A61L2/07
CPCA61K49/22A61L2/0023A61L2202/21
Inventor 袁国正张爱辉喻晓兰李凤秀
Owner 广州广工技术开发有限公司
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