Composition for promoting scar skin repair and preparation method thereof

A technology for skin repair and composition, which is applied in the field of composition and its preparation for promoting scar skin repair. It can solve the problems that the production and use cycle is easy to exceed the active storage period, the product utilization rate is small, and the stability is poor, so as to improve product utilization. The effect of improving the rate, prolonging the shelf life, and repairing skin scars

Inactive Publication Date: 2020-01-14
上海龙禧投资有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, active peptides are added to most products to eliminate scars, but active peptides are active substances that are sensitive to ambient temperature, have poor stability and are easily inactivated
Therefore, when it is used as a composition, the production and use cycle is easy to exceed its active shelf life, resulting in very little product utilization

Method used

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  • Composition for promoting scar skin repair and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0055] The second aspect of the present invention provides the preparation method of the above-mentioned composition for promoting scar skin repair, the steps include: heating dextran, penetration enhancer, and water to 60-75°C and stirring evenly, and then cooling down to below 40°C Add white birch extract, biologically active peptides, vitamin A compounds, and stir well.

[0056] Implementation path

[0057] The compositions for promoting the repair of scarred skin according to the present invention facilitate the administration of the compounds to the organism. It can be implemented in various ways, for example, including but not limited to, injection, spraying, topical application and other implementations.

[0058] Composition / Preparation

[0059] The composition for promoting scarred skin repair of the present invention can be used in various applications to form various formulations without any particular limitation. For example, the composition may be formulated...

Embodiment 1

[0069] Example 1 provides a composition for promoting the repair of scarred skin, which includes 1% birch extract and a compound mixture of biologically active polypeptides, 3% vitamin A compounds, and 10% dextran , 15% penetration enhancer, balance water.

[0070] The mass ratio of the birch extract to the biologically active polypeptide is 1:5;

[0071] The birch extract is betulin;

[0072] The biologically active polypeptide is a mixture of hexapeptide and tripeptide, and the hexapeptide accounts for 70wt% of the biologically active polypeptide; the hexapeptide is a mixture of acetyl hexapeptide-8 and palmitoyl hexapeptide-19, and the acetyl hexapeptide- 8. The mass ratio of palmitoyl hexapeptide-19 is 3:1; the tripeptide is tripeptide-1;

[0073] The vitamin A compound is a mixture of vitamin A alcohol and vitamin A alcohol palmitate, and the mass ratio of vitamin A alcohol and vitamin A alcohol palmitate is 6:1;

[0074] The dextran is oat glucan;

[0075] The penetr...

Embodiment 2

[0078] Example 2 provides a composition for promoting the repair of scarred skin, which includes 4% birch extract and a compound mixture of biologically active polypeptides, 1% vitamin A compounds, and 20% dextran , 30% penetration enhancer, and the balance water.

[0079] The mass ratio of the birch extract and the biologically active polypeptide is 1:3;

[0080] The birch extract is betulinic acid;

[0081] The biologically active polypeptide is a mixture of hexapeptide and tripeptide, and the hexapeptide accounts for 50wt% of the biologically active polypeptide; the hexapeptide is a mixture of acetyl hexapeptide-8 and palmitoyl hexapeptide-19, and the acetyl hexapeptide- 8. The mass ratio of palmitoyl hexapeptide-19 is 1:1; the tripeptide is tripeptide-1;

[0082] The vitamin A compound is a mixture of vitamin A alcohol and vitamin A alcohol palmitate, and the mass ratio of vitamin A alcohol and vitamin A alcohol palmitate is 10:1;

[0083] The dextran is oat glucan;

...

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Abstract

The invention relates to the technical field of cosmetics, in particular to a composition for promoting scar skin repair and a preparation method thereof. The composition for promoting the scar skin repair includes, in percentage by mass, a 0.5 to 5% birch extract and a biological active polypeptide compound which serve as active ingredients. The birch extract is selected from one or more of betulin, betulinic acid, betulin derivatives, and betulinic acid derivatives. The invention provides the composition for promoting the scar skin repair, and the composition includes the birch extract and the biological active polypeptide compound which serve as active ingredients. Together with the remaining components, the composition solves the conditions that active polypeptides are easily aggregated, a turbid composition system is caused, and the active polypeptides are difficult to absorb and easy to layer, thereby improving the overall stability, extending the shelf life of the product and further improving the product utilization rate. At the same time, through the synergistic effect of the active ingredients and a vitamin A compound, the composition can effectively repair skin scars.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a composition for promoting scarred skin repair and a preparation method thereof. Background technique [0002] Acne is usually caused by increased sebum production from increased androgen production. Specifically, sebum produced by androgens and hyperkeratosis of the hair follicles can lead to narrowing or, in severe cases, clogging of the hair follicles. When the hair follicles become narrowed or blocked, the follicles cannot produce sebum and produce microcomedone. Under these conditions, the anaerobic bacterium Propionibacterium acnes growing in the hair follicles may cause inflammation. Inflammation results in erythema, itching, swelling and, in severe cases, hyperpigmentation. If the pimple is squeezed or pressed hard, the inflammation may worsen into a breakout. At the same time, acne scars are likely to develop into tissue damage. [0003] Currently, the researcher...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/63A61K8/64A61K8/67A61Q19/00A61Q17/00A61P17/02A61P17/10
CPCA61K8/63A61K8/64A61K8/671A61K8/9789A61P17/02A61P17/10A61Q17/005A61Q19/00
Inventor 付涛
Owner 上海龙禧投资有限公司
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