Bacteriostatic gel and preparation process thereof
A technology of gel and octylphenol polyether, which is applied in the direction of antifungal agents, antibacterial agents, local antibacterial agents, etc., can solve the problems of users' allergies or stress reactions, prevent allergies and teratogenic phenomena, and inhibit Pathogens, good experience effect
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[0034] The preparation of the antibacterial gel includes the configuration of two groups of components. First, the antibacterial active component is configured, and the solvent is mixed with the active antibacterial component to obtain component A. The pH value of component A needs to be adjusted. Since there are only water, octoxynol and benzalkonium chloride in component A, the pH value is low, and it is necessary to adjust the pH value by adding caustic soda by titration, so as to adjust the pH value of component A to be consistent with the vaginal compatible with the pH value within. The preparation of component B is to mix the other half of the solvent with the active salt solution and thickener, then stir evenly and completely dissolve to prepare component B. After mixing component A and component B, fully Stir to obtain antibacterial gel.
[0035] Specifically, in the step of "adding caustic soda to component A to adjust the pH value", the final pH value is 5.0-5.8, wh...
Embodiment 1
[0039] Prepare 96.55% double distilled water by weight to volume ratio, place half of the double distilled water in the container and add 0.55% active antibacterial ingredients (wherein by mass ratio, octylphenol polyether-11 and octylphenol polyether-11 25: benzalkonium chloride=7:1), stirring and dissolving to obtain component A, the stirring speed is 400r / min;
[0040] Slowly add caustic soda to component A to adjust the pH value to 5.6;
[0041] Put the other half of double distilled water in the container, add 0.9% active salt solution (wherein the volume ratio of sodium chloride solution and potassium chloride solution is 14:1) and 2% hydroxypropyl methyl Cellulose, stirring and dissolving to obtain component B, the stirring speed is 400r / min;
[0042] Component A and component B were stirred and mixed to obtain the antibacterial gel, and the stirring rate was 400 r / min. 1, the bacteriostatic gel that embodiment 1 obtains is carried out the content detection before and...
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