Composition for removing acne and preparation method thereof
A composition and acne technology, applied in the direction of drug combination, skin care preparations, medical preparations containing active ingredients, etc., can solve the problems of increasing the cost of removing impurities, extracting a large amount, and not performing quality control, etc., to achieve retention Effective substance activity, accelerated onset time, good drug activity effect
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Embodiment 1
[0044] 1. Put 20 parts of Cortex Phellodendron into a pulverizer, pulverize to be less than or equal to 80 mesh (sieve); put into pure water 6 times the weight of the medicinal material, stir to suspend and disperse the particles;
[0045] 2. Jet cooking the material liquid in 1, the material is in the middle, steam is injected from both sides, the steam outlets on both sides are at an angle of 120°, the steam temperature is 140°C, the material flow rate is 15L / min, and the steam flow rate on both sides is 20L / min min;
[0046] 3. Pour the feed liquid in 2 into the colloid mill, the grinding gap gradually decreases from the maximum (the gap finally reaches 1 micron), heat the feed liquid to 40°C, add cellulase by 0.8% of the weight of the medicinal material (enzyme activity unit 10000U / g), adjust the pH to 4.5, stir for enzymolysis and grind for 60 minutes;
[0047] 4. Add butanediol which is 6 times the weight of Phellodendron cortex in 1, and 20 parts of thyme, mix well, c...
Embodiment 2
[0053] 1. Put 15 parts of Cortex Phellodendron into a pulverizer, pulverize to less than or equal to 80 mesh (sieve); put in pure water 4 times the weight of the medicinal material, stir to suspend and disperse the particles;
[0054] 2. Put the material liquid in 1 into the steam injection device for jet cooking, the steam temperature is 120°C, the material flow rate is 20L / min, and the steam flow rate on both sides is 25L / min;
[0055] 3. Pour the material liquid in 2 into the colloid mill, the grinding gap gradually decreases from the maximum (the gap finally reaches 1 micron), heat the material liquid to 30 ° C, add cellulase by 0.1% of the weight of the medicinal material (enzyme activity unit 10000U / g), adjusting the pH to 5.5, stirring for enzymolysis and grinding for 60 minutes;
[0056] 4. Add butanediol which is 4 times the weight of Phellodendron cortex in 1, and 15 parts of thyme, mix well, continue grinding and extracting at 55°C for 0.5h;
[0057] 5. The feed l...
Embodiment 3
[0060] 1. Put 17.5 parts of Cortex Phellodendron into a pulverizer, pulverize to be less than or equal to 80 mesh (sieve); put in pure water 5 times the weight of the medicinal material, stir to suspend and disperse the particles;
[0061] 2. Put the material liquid in 1 into the steam injection device for jet cooking, the steam temperature is 130°C, the material flow rate is 18L / min, and the steam flow rate on both sides is 22L / min;
[0062] 3. Pour the feed liquid in 2 into the colloid mill, the grinding gap gradually decreases from the maximum (the gap finally reaches 1 micron), heat the feed liquid to 50°C, add cellulase by 0.5% of the weight of the medicinal material (enzyme activity unit 10000U / g), adjusting the pH to 4.0, stirring for enzymolysis and grinding for 60 minutes;
[0063] 4. Add butanediol which is 4 times the weight of Phellodendron cortex in 1, and 17.5 parts of thyme, mix well, and continue grinding and extracting at 30°C for 0.5h;
[0064] 5. The feed ...
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