315 results about "Caprylates" patented technology

The invention relates to a lubricant for drilling fluid, which essentially solves the problems of the prior art that the lubricant for drilling fluid has poor lubricating property in the high-density drilling fluid. The lubricant for drilling fluid comprises the following components calculating by weight percentage: a) 1 to 35 percent of long-chain organic acid oiliness agent; b) 1 to 35 percent of synthetic ester oiliness agent; c) 0.1 to 8 percent of emulsifier; and d) 25 to 90 percent of base oil; in which the synthetic ester oiliness agent is selected from at least one of isooctyl stearate, butyl isostearate, trimethylolpropane trioleate, trimethylolpropane palm kernel ester, trimethylolpropane ethylhexoate, neopentyl glycol oleate, methyl laurate or pentaerythritol caproate, therefore, the technical proposal solves the problem preferably, and can be used in the industrial production of lubricant for drilling fluid.

An improved process for the purification of antibodies from human plasma or other sources is disclosed. The process involves suspension of the antibodies at pH 3.8 to 4.5 followed by addition of caprylic acid and a pH shift to pH 5.0 to 5.2. A precipitate of contaminating proteins, lipids and caprylate forms and is removed, while the majority of the antibodies remain in solution. Sodium caprylate is again added to a final concentration of not less than about 15 mM. This solution is incubated for 1 hour at 25° C. to effect viral inactivation. A precipitate (mainly caprylate) is removed and the clear solution is diluted with purified water to reduce ionic strength. Anion exchange chromatography using two different resins is utilized to obtain an exceptionally pure IgG with subclass distribution similar to the starting distribution. The method maximizes yield and produces a gamma globulin with greater than 99% purity. The resin columns used to obtain a high yield of IgG retain IgM and IgA. IgA and IgM may be eluted from these resins in high yield and purity.

The invention relates to a waterborne fluororesin nonstick coating, which is formed by 40 to 70 portions of modified polyte-trafluoroethylene (PTFE) water base resin, 10 to 30 portions of high temperature resistance pigment, 1 to 5 portions of fluororesin additive, 1 to 5 portions of surfactant and 20 to 40 portions of antiwear filler. The waterborne fluororesin nonstick coating uses synthesis propylene acid water base resin for modifying trafluoroethylene PTFE water base resin, adopts acrylic acid fat second polymerization method and does not use an addition agent, the entire fluorine caprylate compound which is harmful to human body in the modification process; the modified resin forms mosaic and perforating network structure, has good temperature dispersing region, solves the problem of the adhesiveness of the coating and the base material and the problems of baking and cracking, thus improving the hardness of nonstick coating. The NU aqueous fluorine resin of the invention does not stick to coating, can be coated on the surfaces of a microwave oven, an electric cooker, a nonstick pan and an electromagnetic pan, etc. to play the roles of protecting the surfaces from being stuck with food, and causing food and aluminum and other metals to be isolated.

The invention discloses a skin barrier repairing preparation. The preparation is prepared from the following components: deionized water, sucrose stearate, phytosteryl isostearate, vitamin E, glycerinum, butylene glycol, 1,2-pentylene glycol, octyldodecanol, polydimethylsiloxane, hydrogenated polyisobutene, oleic acid, linoleic acid, ceramide 2, ceramide 3, ceramide 6II, sodium hyaluronate, xanthan gum, disodium EDTA, acrylates C10-30 alkyl acrylate crosslinked polymer, allantoin and sorbitan caprylate. The invention further provides a method for preparing the skin barrier repairing preparation. According to the preparation method, the problem of dissolving compound ceramide can be solved, the impact of ceramide crystallization on stability under a low-temperature condition can be reduced, the stability of the preparation can be improved, and other skin repairing components can be added and compounded with the compound ceramide. The skin barrier repairing preparation has an excellent product formula stability and a multiple repairing effect on the skin barrier.

The invention belongs to the technical field of cosmetics, and particularly discloses double-layer essence with repair and anti-aging functions. The double-layer essence comprises, by weight, 1.0%-2.0% of PEG-40 (polyethylene glycol-40) hydrogenated castor oil, 5%-19% of methyl trimethicone, 4%-6% of dicaprylyl carbonate, 0.5%-1.5% of cetyl dimethicone, 0.5%-1.5% of helianthus annuus seed oil, 3%-9% of glycerin, 0.1%-0.15% of sodium hyaluronate, 0.5%-1.5% of myrothamnus flabellifolia leaf / stem extract, 1%-3% of polypeptides with palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, 0.5%-1.5% of lactobacillus ferment lysate, 1%-3% of glycosphingolipid, 0.8%-1% of mixtures of glycerol caprylate, p-hydroxy phenyl ethyl ketone and glyceryl laurate and the balance water. The double-layer essence has the advantages that the double-layer essence which is a novel ultralow-viscosity double-layer system is unique in structure and convenient to use; formulas and structures of the double-layer essence are optimized, and accordingly the double-layer essence is free of potential irritation and allergy sources such as perfume and preservatives, is in mild and non-irritant formulas and has the excellent repair and anti-aging functions.

The invention discloses a compound preservative containing glycerol caprylate and decoyl hydroximic acid and a preparation method of. The compound preservative is characterized by being prepared from the following ingredients in percentage by weight: 0.5%-15% of caprylin, 1%-15% of the decoyl hydroximic acid and 70-98.5% of dihydroxy alcohol. The compound preservative has favorable antibacterial effects on gram-positive bacteria, gram-negative bacteria, mold, microzyme and the like, and can be used for improving the product stability.

The invention relates to an essence with a self-preservative characteristic. The essence comprises the following components in parts by weight: A. 64.2-93.25 parts of a water component; B. 0.5-2.5 parts of a composite plant preservative component; C. 0.5-3 parts of a hexanediol component; D. 0.05-0.5 part of a xanthan gum component; E. 0.05-0.3 part of a sclerotium gum component; F. 0.5-1.5 parts of a natural preservative component; G. 0.5-1.5 parts of a glycerol caprylate and caprylyl glycol component. The scheme has the advantages that the components are reasonable, moist and anti-inflammatory, the self-preservative characteristic is provided, and the like.

The invention discloses an anticorrosive component-free composition having an antibiosis effect. The composition comprises, by weight, 20-45% of p-hydroxyacetophenone, 3-10% of glycerol caprylate, 6-15% of caprylhydroxamic acid, 21-40% of propylene glycol, 0.5-1.5% of caprylyl glycol and 5-15% of ethylhexylglycerin, and the sum of the weight percentages of all above components is 100%. The anticorrosive component-free composition having the antibiosis effect has the advantages of no irritation, non-allergy, protruding antibiosis effect, harmlessness to human bodies, and no toxic or side effects, and can be safely applied to cosmetics. The invention also discloses a preparation method of the anticorrosive component-free composition having the antibiosis effect. The preparation method of the composition has the advantages of few steps, simple flow, and safety in operation. The invention further discloses an essence and a preparation method thereof. The essence has the advantages of good antibiosis effect, wide antibiosis range, no toxicity, harm or irritation, and high use safety, and the preparation method of the essence has the advantages of few steps, simple flow, and safety in operation.

Certain surfactants suitable for use alone to dissolve a water-insoluble component in compositions is described for providing VOC-free compressed gas aerosol compositions. The compositions include water-insoluble component(s), a surfactant and water. The water-insoluble component(s) can be active agent(s), such as fragrance(s) and / or an insecticide(s). The surfactant is present as a single surfactant which, in the absence of a solvent, dissolves or disperses the water-insoluble component(s) and provides a homogenous blend in water which provides a stable compressed gas emulsion. The surfactant is an anionic surfactant or a nonionic surfactant, in particular nonionic alkylpolyglycosides; nonionic cocoglucoside; nonionic alkylene oxide extended chain alkylpolyglycosides; anionic sodium lauryl ether sulfate (SLES), nonionic C13-C15 oxoalcohol ethoxylate with 8 ethylene oxides (EO), nonionic C12-C14 secondary alcohol ethoxylate with 7EO or 12EO, polyethylene glycol (PEG) hydrogenated castor oil wherein the PEG is PEG-60 or PEG-40, polyglyceryl-10 laurate and polyglyceryl-6 caprylate.

The present invention is fluoric elastomer with fluorine content higher than 70 %. The fluoric elastomer consists of the following copolymerized units: 1, 1-difluoro ethylene 30-60 wt%, perfluoro propylene 20-40 wt% and tetrafluoro ethylene 20-40 wt%. The present invention also relates to the preparation process of the fluoric elastomer with high fluorine content, and the preparation process is one emulsion polymerization process with water as medium, low molecular weight esters as chain transferring agent, persulfate as initiator, perfluoro caprylate as dispersant and borax as pH regulator.

The invention discloses a moisturizing lotion without a preservative, and a preparation method thereof. The moisturizing lotion is prepared from the following components in percentage by weight: 10 to 20 percent of oil substance, 1 to 5 percent of emulgator, 0.1 to 1 percent of carbomer, 1 to 15 percent of polyhydric alcohol, 0.01 to 0.2 percent of sodium hyaluronate, 0.05 to 3 percent of panthenol, 0.05 to 3 percent of allantoin, 0.1 to 1 percent of glycerol caprylate, 0.1 to 2 percent of isooctyl glycerinum, 0.01 to 0.2 percent of disodium EDTA, 0.1 to 5 percent of traditional Chinese medicine extract composite, 0.01 to 1 percent of aminomethyl propanol, 0.01 to 0.5 percent of essence, and the balance of water to reach 100 percent. The moisturizing lotion without the preservative does not contain any preservative specified by Cosmetic Safety Technology Standard (Edition 2015), and is good in moisture retention, low in irritation, and safer to a human body.

The invention discloses multiple-plant-extract lip pomade and a preparation method thereof. The multiple-plant-extract lip pomade contains the following raw materials in parts by weight: 19 parts of olive squalane, 14 parts of diisostearyl alcohol malate, 5 parts of dimeric pentaerythritol tri-polyhydroxyl stearate, 5 parts of jojoba esters, 5 parts of tridecanol trimellitate, 5 parts of caprylate / decanoate triglyceride, 5 parts of meadowfoam seed oil, 5 parts of adansonia digitata tree seed oil, 5 parts of phytosterol oleate, 5 parts of C10-30 acid cholesterol / lanosterol mixed ester, 4 partsof polyethylene, 3 parts of candelilla wax, 3 parts of hydrogenated castor oil dimeric linoleate, 3 parts of polyglycerol-2-tri-isostearate, 2.5 parts of beeswax, 2.5 parts of earth wax, 4 parts of humectant, 2 parts of emollient, 2 parts of prunus avium seed oil, 0.5 part of tocopherol and 0.5 part of antioxidant. The multiple-plant-extract lip pomade has very good repairing, moisture preservingand cheilogramma dispelling actions and can be used for durably nourishing and relaxing skin and keeping lip skin healthy.

A synthetic process of a rhodium octanoate dimer comprises the following two steps: firstly, a DMF solvent of rhodium chloride is added to acetate solution of acetate dimethylamine to generate (Me2NH2]2[Rh2(CH3COO)4Cl2) which is heated in hot water to prepare (Rh2(CH3COO)4).2H2O; then the (Rh2(CH3COO)4).2H2O is dissolved in hot toluene to obtain the rhodium acetate dimer; secondly, the rhodium octanoate dimer is synthesized by a soxhlet extractor. By adopting the method of exchanging and separating the octanoic acid and the acetate dimmer at the same time, chlorobenzene backflow is utilized to keep the system at constant temperature to obtain a pure product of the rhodium octanoate dimer. The synthetic process is characterized by high reaction yield, high product purity, less loss of precious metals, etc.

The invention discloses a new method for synthesizing rhodium caprylate (II), which is characterized by comprising the following steps: dissolving a certain amount of rhodium chloride in water; adding 120 to 300 theoretical percent of octylic acid into the water, and adjusting the pH valve of the obtained solution to between 4.5 and 6.5 by using alkali; heating the solution to the temperature of between 90 DEG C and 100 DEG C, reacting for 3 to 5 hours, and filtering the solution when the solution is hot; and fully washing by using water, and drying to obtain a green rhodium caprylate (II) product. The method for synthesizing the rhodium caprylate (II) has the advantages of high reaction speed, high yield (over 95 percent), high product purity (over 99 percent), small environmental pollution, and suitability for industrial production.

The invention provides a repairing eye cream with an anti-blue-light effect and a preparation method thereof. The repairing eye cream with the anti-blue-light effect is prepared from the following functional components of glycerol, butanediol, EDTA disodium, avocado butter, cetostearyl alcohol, isopropyl myristate, bis-PEG-18 methyl ether dimethyl silane, neopentyl glycol dicaprylate, DC9040 silicon elastomers, a MONTANOV68 emulsifier, a thickening agent SEPINOVEMT10, an emulsifying agent SIMULSOL165 and deionized water, wherein the functional components comprise xanthophyll, a bifidus yeast fermentation product spore lysate, acetyl hexapeptide-8, acetyl tetrapeptide-5, palmitoyl pentapeptide-4, a cocoa seed extract, nicotinamide, a centella asiatica extract, borneol, zinc carbonate hydroxide, amber powder, pearl powder, borax, tocopheryl acetate, glucosyl hesperidin, allantoin and fullerene. The repairing eye cream with the anti-blue-light effect not only has the effect of resisting blue light invasion, but also has the repairing effect, and is high in application prospect.

The invention discloses a multi-effect skin-tendering mask which comprises the following components by weight: 67.55 parts of water, 4 parts of butanediol, 0.2 part of allantoin, 0.4 part of hydrolytic Sclerotium Gum, 0.1 part of disodium, 0.1 part of sodium hyaluronate, 0.15 part of poly(sodium L-glutamate), 3 parts of betaine, 5 parts of licorice extract, 8 parts of cherry blossom extract, 5 parts of North American witch hazel water, 0.5 part of oat seed extract, 2 parts of nicotinamide, 0.5 part of Aloe barbadensis Mill gel, 2.2 parts of beta-glucan, 0.5 part of isoascorbic acid, 2 parts ofglycerol caprylate, 4.5 parts of propylene glycol and 0.4 part of caprylhydroxamic acid. The multi-effect skin-tendering mask has the advantages of non-preservative formula and good skin-tendering effect, and is capable of effectively increasing skin moisturizing ability, promoting skin health, increasing skin transparency, enhancing skin immunity, making skin full and elastic, and making skin smooth and smooth.

The invention discloses a skin care cream with an eczema repair function. The skin care cream is prepared from the following materials: hydrogenated lecithin, potassium lauryl phosphate, camellia-seed oil, evening primrose oil, cetostearyl alcohol, olive fruit oil, vitamin E, phytosterol oleate, polydimethylsiloxane, ethylenediamine tetraacetic acid disodium, polyglycerol-10, Carbomer, arginine, sodium hyaluronate, a creased mulan bark extract, a Japanese thuja branch extract, a shaddock peel extract, a glycyrrhiza glabra root extract, a purslane extract, a centella extract, a pomegranate extract, saccharide isomerate, glycerol caprylate, caprylhydroxamic acid and water. The skin care cream with the eczema repair function has a mild nature, is low in irritation and is high in acid and alkali stability and cold and heat resistance.

The invention belongs to the technical field of fine chemical engineering, and discloses fatty glyceride as well as a preparation method and an application thereof. The fatty glyceride is prepared from the following components by mole percent: 20-60mol% of glycerinum, 5-50mol% of component A, 1-50mol% of component B and 0-10mol% of component C, wherein the component A is octanoic acid, methyl caprylate or ethyl caprylate, the component B is decanoic acid, methyl decanoate or ethyl decanoate and the component C is saturated fatty acid, fatty acid methyl ester or fatty acid ethyl ester with 12-16 carbon atoms. The preparation method comprises the following steps: carrying out a reaction on the components and a catalyst at a normal pressure at 130-180 DEG C for 1-6 hours in nitrogen; then, carrying out a decompression reaction at 130-210 DEG C for 1-6 hours and dehydrating to obtain the fatty glyceride. The fatty glyceride obtained has an extremely good synergic tackifying effect and good foaming characteristic and foaming behavior and can be used as a thickener for synthesis of daily detergent products and cosmetics.

The invention relates to the field of hair care, and concretely relates to an essence for care of scalp and hair root as well as a preparation method thereof. A surfactant is a polyglycerol ester compound, and the amount is as follows: the volume percentage content is 1-10%; the polyglycerol ester compound is compounded from one or more of polyglycerol-6 caprylate, polyglycerol-4 caprate, polyglycerol-3 cocoate, polyglycerol-6 ricinoleate, polyglycerol-6 laurate, polyglycerol-6 myristate, and polyglycerol-10 laurate. Preferably, a preferable combination of the polyglycerol ester compound comprises polyglycerol-6 caprylate, polyglycerol-4 caprate, polyglycerol-3 cocoate, and polyglycerol-6 ricinoleate, and the weight ratio is 1:1:1:1-4:3:1:3. PEG surfactants are not contained, and the essence does not stimulate scalp; washing is not needed, the essence can completely remain on the scalp, so that the scalp problem is solved comprehensively from the root.

This invention relates to a treatment methods and device of low concentration perfluoro ammonium caprylate waste water. Pump clear perfluoro ammonium caprylate waste water into foam separation tower to carry out foam separation, defoam the wastewater tower top spume to gain high concentration perfluoro ammonium caprylate water solution which can be reutilized; gain lower concentration perfluoro ammonium caprulate water solution at tower bottom; use first order nano filter membrane to filter perfluoro ammonium caprylate water solution ejected by tower bottom, condense nano filtration trapped fluid, return it to foam separation tower to carry out foam separation; the permeation liquid of first order nano filter membrane enter secondary nano filter membrane; permeance liquid of secondary nano filter membrane can reach state waste water effluent standard; concentrated solution of secondary nano filter membrane return to first order nano filter membrane; then complete recycling and cleaning of waste water.

The inclusion of soft bee glue capsule includes bee glue, polyglyceryl fatty acid ester, and polyglyceryl caprylate-caprate. The soft bee glue capsule has stable performance, capacity of dispersing in water homogeneously, high bioavailability, high health care function and long preservation period.

The mildew-proof antibiotic polyurethane sponge is prepared with polyol 46.59-78.85 wt%, toluene diisocyanate 19.33-39.2 wt%, water 0.95-3.16 wt%, silicone oil 0.63-1.5 wt%, tin caprylate 0.08-0.19 wt%, amine catalyst 0.06-0.12 wt%, 2, 4, 4'-trichloro-2'-hydroxy-diphenyl-ether 0.01-5 wt%, 2-thiazolyl-4-benzimidazole 0.01-5 wt%. With mildew-proof antibiotic chemicals added, the mildew-proof antibiotic polyurethane sponge may be used in making different kinds of healthful mildew-proof antibiotic products.

The invention discloses an arborescent graft polycaprolactone, and also discloses an arborescent graft polycaprolactone-polyethylene glycol copolymer and application of the copolymer as a drug carrier. In the invention, a novel arborescent graft polycaprolactone-polyethylene glycol copolymer is prepared by preparing a new epsilon-caprolactone derivative (4-benzyloxy-ethoxy-epsilon-caprolactone; BECL) from 1,4-cyclohexanediol used as a raw material, then carrying out ring-opening copolymerization on the BECL and epsilon-caprolactone in the presence of stannous iso-caprylate used as a catalyst, carrying out palladium-carbon catalytic hydrogenation to remove benzyl protecting groups to obtain the arborescent graft polycaprolactone with multiple hydroxyl groups, and finally grafting and introducing hydrophilic polyethylene glycol chain segments to the hydroxyl groups with phosgene as a chain extender. In an aqueous medium, the hydrophobic arborescent graft polycaprolactone shrinks to forma core, and the hydrophilic polyethylene glycol chain segments stretch at the periphery, thus forming a unimolecular micelle. As a drug carrier, the micelle has the advantages of large drug carrying capacity and good stability.

Certain surfactants suitable for use alone to dissolve a water-insoluble component in compositions is described for providing VOC-free compressed gas aerosol compositions. The compositions include water-insoluble component(s), a surfactant and water. The water-insoluble component(s) can be active agent(s), such as fragrance(s) and / or an insecticide(s). The surfactant is present as a single surfactant which, in the absence of a solvent, dissolves or disperses the water-insoluble component(s) and provides a homogenous blend in water which provides a stable compressed gas emulsion. The surfactant is an anionic surfactant or a nonionic surfactant, in particular nonionic alkylpolyglycosides; nonionic cocoglucoside; nonionic alkylene oxide extended chain alkylpolyglycosides; anionic sodium lauryl ether sulfate (SLES), nonionic C13-C15 oxoalcohol ethoxylate with 8 ethylene oxides (EO), nonionic C12-C14 secondary alcohol ethoxylate with 7EO or 12EO, polyethylene glycol (PEG) hydrogenated castor oil wherein the PEG is PEG-60 or PEG-40, polyglyceryl-10 laurate and polyglyceryl-6 caprylate.

The invention is a method of processing ammonium perfluoro octoate in the waste water of teflon dispersion resin production, belonging to the field of processing waste water of teflon dispersion resin production, adopting deposition process to process the waste water, using bivalent metal salts as precipitator and trivalent metal salts as flocculant, processing the waste water by different metallic ions and in different proportions, able to make the concentration of ammonium perfluoro octoate in the obtained clear solution is below 10mg / L, reaching the secondary pollutant effluent concentration (the primary standard 10mg / L ) and completely able to meet the effluent requirements. And the recovered ammonium perfluoro octoate has purity up to 95%, and can be reused in polymerization or act as other fluorine-containing organic matter intermediates.

The invention is a method of recovering ammonium perfluoro octoate in the teflon resin production by dispersion method, belonging to chemical waste gas processing field, comprising bubbling absorbing, condensing, acidifying, and rectifying and purifying of the exhaust gas from cyclic oven, where the recovered ammonium perfluoro octoate has purity able to be up to 99% and can be reused in dispersion polymerization or other fluorine-containing organic matter intermediates. And the concentration of the ammonium perfluoro octoate in the processed gas is below 11mg / m3 (the highest allowable effluent concentration of fluoride is 11mg / m3), and can completely meet the effluent requirements.

The invention discloses a chemical synthetic method for 6, 8-ethyl octylate chloride. The method comprises the steps as follows that: 6-hydroxyl-8-ethyl octylate chloride is dissolved in N, N-dimethylformamide; solution which is dissolved with organic solution of double (trichloride trichloromethyl)-carbonic acid ester is dropped in when in mixing under cold water bath condition; the solution is gradually warmed to 50 to 90 DEG C for reacting for 2 to 8 hours after dropping; and the reaction solution is disposed into 6, 8-ethyl octylate chloride after finishing the reaction. As the invention replaces sulphoxides chloride with double (trichloride trichloromethyl)-carbonic acid ester, the invention produces environment friendly Vilsmeier agent which needs not to be separated in the reaction, and the Vilsmeier agent directly reacts with 6-hydroxyl-8-ethyl octylate chloride to produce 6, 8-ethyl octylate chloride. Besides, the invention has the advantages of advanced technique, rational technological condition, simple and safe operation, high reaction yield, low production cost, low three-waste emission and great implementation value and social and economic efficiency.

The invention relates to rhodococcus baikonurensis and application thereof in preparing optically pure (R)-6-hydroxy-8-chlorocaprylate and other optically active chiral alcohol. The laboratory number of the rhodococcus baikonurensis is ECU1014; the rhodococcus baikonurensis is collected in the China general microbiological culture collection center; the collection number is CGMCC No.7649; the application is as follows: preparing the optically pure (R)-6-hydroxy-8-chlorocaprylate and other optically active chiral alcohol by utilizing the resting cell of the strain as a biocatalyst. The strain disclosed by the invention is used for a biological process for asymmetrically reducing and preparing the optically pure (R)-6-hydroxy-8-chlorocaprylate and other optically active chiral alcohol, has the characteristics of high product concentration, mildness in reaction condition, high atom economy, no need of additionally adding expensive coenzyme, easiness and convenience for operation, easiness for amplification, and the like and has very good industrial application prospect in the production of an (R)-lipoic acid intermediate.

The invention discloses a preparation method of (R)-(+)-lipoic acid and belongs to the field of organic and medicinal chemistry. The preparation method comprises the following steps: (S)-ethyl 6,8-dichloro caprylate and sulfur are fed into a reaction container equipped with a stirring device, the mixture is heated, an aqueous sodium sulphide solution is added dropwise for a cyclization reaction, heat is preserved, then extraction and concentration are performed, and a cyclization liquid is obtained; the cyclization liquid is fed into the reaction container, an alkaline solution is added, a hydrolysis reaction is performed, and a hydrolysate is obtained through cooling; an organic solvent is added to the hydrolysate, pH is regulated with acid, extraction is performed, an organic layer obtained through extraction is washed to be neutral, then an organic solvent is removed through pressure reduction, a primary product is obtained, a mixed solvent is added to the primary product, the mixture is heated and dissolved, a filter aid is added, stirring and adsorption are performed, filtering is performed, a faint yellow liquid is obtained and cooled, crystals are precipitated, and a finished product is obtained. The steps are reduced, and the preparation efficiency is high; raw material consumption is reduced, the optical rotation of (R)-(+)-lipoic acid reaches 117-118 degrees, the ee value is 99.0%-99.5%, the content is higher than 99%, and waste emission is reduced.

The invention relates to a method for synthesizing esters, in particular to a method for synthesizing 1,4-cyclohexanedimethanol diisocaprylate. The preparation steps include: adding terephthalic acid and (4-methylcyclohexyl)methanol into a reaction kettle under superatmospheric pressure at a temperature of 250-400°C, stirring evenly, and fully reacting to obtain terephthalic acid diacetate (4‑methylcyclohexyl) methyl ester; add Zn‑Ge / C catalyst to the reaction system, feed hydrogen, charge hydrogen to carry out hydrogenation reaction, during the hydrogenation reaction, control the hydrogenation rate so that the temperature in the reactor Keep at 100-150°C and pressure at 1-3Mpa, after the hydrogenation reaction, cool to 90-100°C, slowly open the exhaust port to obtain 1,4-cyclohexanedimethanol; the 1 prepared in step 1 , 4-cyclohexanedimethanol and isooctanoic acid are added to the reaction vessel, then superacid catalyst SO42- / TiO2 / Ce is added, the reaction temperature is 100-200 ° C, the reaction is 5-15 h, and the reaction is completed and the heating is stopped to obtain the crude product; Post-processing. The synthetic route is suitable for industrial production.