41 results about "Caprylates" patented technology

The invention relates to the technical field of PVB (polyvinyl butyral) films, in particular to a full-wave-band heat-shielding modified PVB composite film as well as a preparation method and application thereof. The full-band heat shielding modified PVB composite film provided by the invention is of an asymmetric structure and comprises a modified PVB matrix and a heat shielding coating covering one side of the modified PVB matrix, the modified PVB matrix is prepared from the following components: polyvinyl butyral and an epoxy silane coupling agent; the heat shielding coating comprises the following components: CsWO3 nano powder, ZnO nano powder, water-based acrylic resin and a composite dispersion system; the composite dispersion system comprises triethylene glycol di-2-ethylhexoate, polyvinylpyrrolidone and diethylene glycol monobutyl ether. The full-wave-band heat shielding modified PVB composite film provided by the invention can realize 780-2500nm full-wave-band near-infrared high-efficiency barrier, improve the binding force and performance stability of a heat shielding coating, and meet the production requirements of light weight, environmental protection and industrialization at the same time.

Disclosed is a method of reducing fine lines or wrinkles on skin. The method can include applying a topical skin care composition to skin with fine lines or wrinkles. The composition can include lactobacillus ferment, ascorbyl glucoside, Terminalia ferdinandiana fruit extract, Helianthus annuus (Sunflower) seed extract, glycerin, Persea gratissima (avocado) oil, Butyrospermum parkii (shea) butter, coco-caprylate / caprate, Sclerotium gum, sodium benzoate, and tocopherol.

The invention relates to the technical field of polyvinyl butyral modified materials, and discloses a modified PVB (polyvinyl butyral) material based on nano-silica and a preparation method thereof, the modified PVB material is prepared from the following raw materials by weight: 100 parts of polyvinyl butyral resin; 25 to 45 parts of triethylene glycol di-2-ethylhexoate; 0.5 to 5.0 parts of nano silicon dioxide; 0.05 to 0.50 part of a titanate coupling agent; 0.02 to 0.15 part of magnesium stearate; and 1.0 to 5.0 parts of epoxidized soybean oil. The method comprises the following steps: dispersing silicon dioxide by a plasticizer, dehydrating, adding a coupling agent for in-situ grafting, and compounding a stabilizer to prepare mother liquor; infiltrating the mother liquor into the resin to obtain a swelling material; and performing temperature-controlled extrusion. The modified PVB material based on nano silicon dioxide prepared by the invention solves the problems of particle agglomeration and yellowing, and has high transparency, high strength and excellent heat aging resistance.

This invention relates to the field of cosmetic products, specifically disclosing a long-lasting mosquito-repellent lacquerwood wax composite balm. This composite balm, by weight fraction, comprises 20-25 parts by weight of lacquerwood peel wax, 12-18 parts by weight of lemon eucalyptus oil, 3-8 parts by weight of catnip oil, 35-45 parts by weight of a temperature-controlled phase change regulating oil, 5-10 parts by weight of a hydrophobic plant-derived film-forming agent, 2-5 parts by weight of isosorbide dicaprylate, and 0.5-1 part by weight of a fat-soluble antioxidant. The long-lasting mosquito-repellent lacquerwood wax composite balm of this invention achieves a long-lasting and stable release of mosquito-repellent active ingredients, while also possessing suitable temperature-controlled phase change properties, a pleasant skin feel, synergistic mosquito-repellent effects, excellent hydrophobic and sweat-resistant capabilities, and stable storage of natural components.

A sunscreen composition, containing an effective amount of Methylene Blue and / or a hydrate and or a pharmaceutically-acceptable salt thereof; an effective amount of one or more UVA and / or UVB absorbing compounds, with the proviso that Oxybenzone and Octinoxate are excluded; and an excipient base.

The present invention relates to a pharmaceutical composition for oral administration, comprising a bradykinin (BK) B2 receptor antagonist having a chemical structure according to Formula 1, or a salt or solvate thereof, wherein R is deuterium or; #imgabs0# For example, (S)-N-(1-deuterated-1-(3-chloro-5-fluoro-2-((2-methyl-4-(1-methyl-1H-1,2,4-triazol-5-yl)quinolin-8-yloxy)methyl)phenyl)ethyl)-2-(difluoromethoxy)acetamide. The composition comprises a BK B2 receptor antagonist dissolved in a liquid carrier, and the liquid carrier comprises propylene glycol monocaprylate, polyoxyethylene castor oil and propylene glycol. In addition, therapeutic uses of the composition are provided.

The invention relates to a cosmetic or dermatological composition comprising at least one strain of live probiotic bacteria and at least one linear-chain lipodispersible and liposoluble molecule selected from dicaprylyl carbonate, coco caprylate, coco caprate, undecane and / or tridecane, linoleic acid, behenyl alcohol or any mixture thereof, wherein the total content of linear-chain lipodispersible and liposoluble molecules is at least 40% by weight relative to the total weight of the composition.The invention also relates to the use of a lipodispersible and liposoluble linear chain molecule selected from dicaprylyl carbonate, coco caprylate, coco caprate, undecane and / or tridecane, linoleic acid, behenyl alcohol or any mixture thereof to maintain the viability of a live probiotic bacterial strain in a composition intended for topical administration.

The application discloses a stripping agent for a zinc oxide concentrate surface flotation reagent and a preparation method and application thereof, and belongs to the technical field of lead-zinc ore dressing. The stripping agent contains, in terms of mass parts, 30-40 parts of ammonium lauryl sulfate, 10-20 parts of butanediol, 20-25 parts of propylene oxide, 30-35 parts of neopentyl glycol dioctanoate and 40-46 parts of water. The water (40-46 parts), the ammonium lauryl sulfate (30-40 parts) and the butanediol (10-20 parts) are added into a reaction kettle, heated and stirred until the reaction material is heated to 35-45 DEG C to obtain a solution a. The propylene oxide (20-25 parts) is added into the solution a, and stirred at room temperature for 1.5-2.5 hours to obtain a solution b. The neopentyl glycol dioctanoate (30-35 parts) is added into the solution b, and stirred at room temperature for 3-5 hours to obtain a solution c. The pH value of the solution c is adjusted to 4-5, and the solution c is ultrasonically emulsified at 40-45 DEG C for 20-40 minutes, and then cooled to room temperature. When used, the stripping agent is added into ore slurry in an amount of 2-5 times, and stirred at 20-30 DEG C for 40-45 minutes. The stripping agent can effectively strip the surface reagent of the oxidized ore, improve the foaming phenomenon during acid leaching, and reduce the TOC content of the leaching solution.

The invention relates to the technical field of recycled asphalt mixtures, and particularly discloses a recycled asphalt mixture with good durability and a preparation method thereof. The invention discloses a recycled asphalt mixture with good durability. The recycled asphalt mixture is prepared from 60-80 parts of a waste asphalt mixture reclaimed material, 4-7 parts of new asphalt, 15-18 parts of a new aggregate, 2-5 parts of fibers, 3-7 parts of a regenerant and 2-5 parts of filler, wherein the regenerant is prepared from aromatic hydrocarbon oil, triethylene glycol di-2-ethylhexoate, 2-ethylhexyl diphenyl phosphate, dioctyl terephthalate, epoxidized soybean oil, dipropylene glycol methyl ether acetate, polymethylene polyphenyl polyisocyanate, oleic acid hydroxyethyl imidazoline, 0 erucyl amide and barium petroleum sulfonate. The recycled asphalt mixture provided by the invention can effectively resist generation of diseases such as ruts and cracks, the service life of a road is remarkably prolonged, and the maintenance cost of the road is reduced.

A cosmetic preparation containing 4-Hydroxy-3-methoxybenzaldehyde (INCI: vanillin), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI: bis-ethylhexyloxyphenol methoxyphenyl triazine), and dibutyl adipate (INCI: dibutyl adipate) and / or butylene glycol dicaprylate / dicaprate (INCI: butylene glycol dicaprylate / dicaprate).

The invention belongs to the field of cancer medicine preparations, and discloses a polycyclic compound oral preparation and a preparation method thereof. The polycyclic compound oral preparation contains a polycyclic compound as shown in a formula I, polyethylene glycol, propylene glycol monooctoate and polyoxyethylene (40) hydrogenated castor oil, wherein the concentration of the polycyclic compound as shown in the formula I is 0.1-80 mg / mL. According to the polycyclic compound oral preparation disclosed by the invention, the solubility of the polycyclic compound shown in the formula I in an aqueous solution is improved, the preparation can obtain a self-emulsifying particle size smaller than 100nm in the aqueous solution, and meanwhile, the polycyclic compound oral preparation has good stability, dissolution rate, oral bioavailability, body tolerance or safety of auxiliary materials, low cost, easiness in production and storage resistance, # imgabs0 #

The pharmaceutical compositions described herein include a suspension which comprises an admixture in solid form of a therapeutically effective amount of a therapeutic agent and at least one salt of a medium chain fatty acid and a hydrophobic medium, e.g. castor oil or glyceryl tricaprylate or a mixture thereof. The pharmaceutical compositions described herein contain medium chain fatty acid salts and are substantially free of alcohols. The pharmaceutical compositions may be encapsulated in a capsule. Methods of treating or preventing diseases by administering such compositions to affected subjects are also disclosed.

The present application provides a kind of sorbitan ester antiseptic additive-free replacement sorbitan monoisopropyl adipate and its synthesis method, with sorbitol, 2-propyl heptanoic acid as raw material, by one-step reaction to obtain the target product sorbitan monoisopropyl adipate. By characterizing its sterilization, washing and emulsification, etc. The results show that the preservative and bacteriostatic performance of sorbitan monoisopropyl adipate reaches and is better than the level of currently marketed sorbitan ester, can replace sorbitan ester, and has good emulsification, washing function. The synthesized sorbitan monoisopropyl adipate is used in detergent, can replace part of traditional surfactant, through decontamination power evaluation and microbial test, the washing effect is good, the detergent after replacement does not need to add conventional preservative, can pass microbial challenge test.

The invention relates to the field of cosmetics, in particular to cleansing oil and a preparation method of the cleansing oil. Comprising the following components in percentage by weight: 15%-25% of cetyl ethyl hexanoate, 2%-5% of diisostearyl malate, 8%-12% of ethylhexyl palmitate, 15%-25% of isohexadecane, 10%-20% of rice chaff oil, 0.1%-1% of simmondsia chinensis seed oil, 0.1%-1% of meadowfoam seed oil, 0.1%-1% of silybum marianum seed oil, 0.1%-1% of macadamia nut seed oil, 2%-5% of PEG-7 glyceryl cocoate and 10%-15% of polyglycerol-10 dioleate. The invention discloses cleansing oil and a preparation method thereof, and the cleansing oil comprises the following components in percentage by weight: 20-30% of cleansing oil, 3-6% of polyglycerol-dioctanoate, 0.01-0.1% of ascorbyl tetraisopalmitate, 0.05-0.3% of tocopheryl acetate and 0.1-0.3% of bisabolol. The cleansing oil and the preparation method thereof provided by the invention solve the problems that the cleaning efficiency and the mildness of the existing cleansing oil are contradictory, and the existing cleansing oil lacks antioxidant and repairing effects.

The application provides a water-oil double-layer penetration-promoting cosmetic composition and a preparation method thereof, and relates to the cosmetic field. The raw materials of the water-oil double-layer penetration-promoting cosmetic composition include 5-30% of an oil phase and 70-95% of an aqueous phase according to a total mass of 100%. The raw materials of the aqueous phase include dipropylene glycol, glycerol glucoside and water. The raw materials of the oil phase include caprylic capric triglyceride and isosorbide dioctanoate. The isosorbide dioctanoate in the water-oil double-layer penetration-promoting cosmetic composition constructs a lipid microchannel, the dipropylene glycol enhances the hydration of the stratum corneum, and the glycerol glucoside activates AQP3 water channel protein. The three channels synergistically improve the penetration efficiency without damaging the integrity of the skin barrier. The penetration-promoting agent has strong broad-spectrum penetration-promoting ability for different polar functional ingredients, the penetration-promoting effect is stable, and the penetration-promoting agent can be stably distributed in the oil and water phases.

This invention discloses a naturally derived anti-aging moisturizing lotion and its preparation method, relating to the cosmetics field. The anti-aging moisturizing lotion comprises phase A, phase B, and phase C; phase A includes a natural oil-in-water emulsifier, dioctyl carbonate, plant-derived squalane, emollients, coconut oil-caprylate / caprylate, behenyl alcohol, sorbitan caprylate, and Bidens trifoliata extract; phase B includes a solvent, glycerin, 1,3-propanediol, and a thickener; phase C includes sodium hyaluronate, 1,2-pentanediol, Globe amaranth extract, sea fennel callus culture filtrate, and a skin conditioning agent. The anti-aging moisturizing lotion of this application does not cause skin irritation and is suitable for sensitive skin; it also has excellent water retention properties, improving skin elasticity, reducing fine lines or wrinkles, and effectively reducing and decomposing melanin synthesis in the skin, thus achieving true anti-aging effects.

The present invention primarily relates to the use of a fatty acid ester or of a mixture of two or more fatty acid esters or of a mixture comprising one or more fatty acid esters, wherein the fatty acid ester or one, two, three or more, preferably all, of the fatty acid ester(s) is / are selected from the group consisting of 3-hydroxypropyl caprylate, glyceryl monocaprylate, 3-hydroxypropyl undecylenate and glyceryl monoundecylenate, for modifying the sensory properties of a skin care product. The present invention further relates to methods for modifying the sensory properties of a skin care product as well as to methods for manufacturing a skin care product and to particular skin care products.

The invention discloses an anti-dandruff shampoo and a preparation method thereof, and relates to the technical field of daily products. When the anti-dandruff shampoo is prepared, firstly, chitosan, formic acid and formaldehyde react to obtain N, N-dimethyl chitosan; then enabling N, N-dimethyl chitosan to react with epichlorohydrin and arginine in sequence to obtain a modified chitosan surfactant; pulverizing clove, and extracting to obtain eugenol dry powder; and finally emulsifying and mixing glycerol, sodium cocoyl glutamate, sorbitan octoate, glyceryl laurate, the eugenol dry powder, the modified chitosan surfactant, citric acid and phenoxyethanol to prepare the anti-dandruff shampoo. The anti-dandruff shampoo prepared by the invention has excellent anti-dandruff property, moisture retention and mildness.

The invention discloses carboxylated beta-GP bi-crosslinking ABPA, a tearable mask and a preparation method, relates to the technical field of skin care products, and solves the problem that the mask is difficult to realize the synergism of film-forming property, tearable property, biocompatibility and multiple anti-light aging effects. The method comprises the following steps: reacting a beta-GP solution with a succinic anhydride solution, repeatedly centrifuging and washing after the reaction is ended, and freeze-drying to obtain beta-GP-COOH; 7-hydroxynaringenin phosphate and trehalose hexaprylate are dissolved in a PBS buffer solution, and a composite activation solution is obtained; dissolving beta-GP-COOH in a PBS buffer solution, transferring the solution to a water bath at 30 DEG C, and dropwise adding the composite activation solution into the system for an activation reaction; dropwise adding an ABPA solution into the activated system while stirring, and transferring into a microwave reaction tube for reaction; then carrying out dialysis; and finally, carrying out freeze-drying operation to obtain the carboxylated beta-GP bi-crosslinked ABPA. The mask provided by the invention can be used for improving multiple photoaging skin injury.

This invention relates to the field of synthetic ester base oil technology, and particularly to a synthetic ester base oil comprising trimethylolpropane trioctanoate, trimethylolpropane dioctanoate-decanoate, trimethylolpropane dioctanoate-decanoate, and trimethylolpropane tridecanoate. Based on the total mass of the synthetic ester base oil, the mass ratio of these four components is 0.1~4:1~6:1~5:1. The synthetic ester base oil also includes these four components, and the proportions of each component can be adjusted to meet different performance requirements.

Pharmaceutical microemulsion composition of clarithromycin with improved stability, bioavailability and antimicrobial activity against Helicobacter pylori, comprising: (a) 1 gram of clarithromycin as active pharmaceutical ingredient; (b) 8 grams of an oil phase consisting of a 1:1 mixture of glyceryl tricaprylate and peppermint oil; (c) 40 grams of a surfactant mixture (Smix), the surfactant being Tween 80 and the co-surfactant being Transcutol P, present in a ratio optimized to maintain an isotropic and thermodynamically stable microemulsion; (d) 52 grams of an aqueous phase comprising purified water; wherein the microemulsion composition is characterized by a mean droplet size of less than 30 nanometers, a viscosity in the range of 3.91 to 18.97 centipoise (cps), and a pH in the range of 4.56 to 7.06; and wherein the composition provides improved solubility, bioavailability, and physicochemical stability of clarithromycin under gastric pH conditions, thereby improving therapeutic efficacy against Helicobacter pylori.

The invention discloses an antimicrobial composition and application thereof. The antimicrobial composition comprises (a) capryloyl hydroxamic acid; and (b) a second antimicrobial preparation, wherein the second antimicrobial preparation is selected from at least one of p-hydroxyacetophenone, glycerol caprylate and ethylhexylglycerin; according to the antimicrobial composition, the synergistic interaction between the capryloyl hydroxamic acid and the second antimicrobial preparation is fully exerted, the antimicrobial effect is remarkably improved, and the antimicrobial composition can be used in daily chemical products, cosmetics, personal care compositions or cleaning compositions and has the advantages of being low in dosage, safe, effective, natural, low in irritation and the like.

The application discloses a water-based type flux for a photovoltaic N-type cell 0BB assembly and a preparation method thereof, and belongs to the technical field of fluxes. The flux is prepared from the following raw materials in parts by weight: deionized water 30-60 parts, an alcohol solvent 30-50 parts, a high-boiling-point solvent 2-8 parts, an organic acid 1-4 parts, a surfactant 0.1-1 part, an antioxidant 0.1-1 part, a corrosion inhibitor 0.1-1 part, allulose 0-1 part and trimethylolpropane trioctanoate 0-1 part. The application solves the problem of the negative influence of the traditional flux applied in the photovoltaic N-type cell 0BB assembly on the tensile force of the heat-resistant glue and the alloying of the fine grid.

4-Hydroxy-3-methoxybenzaldehyd (INCI: Vanillin), 2,4-Bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazin (INCI: Bis- Ethylhexyloxyphenol methoxyphenyl Triazine), sowie Dibutyladipat (INCI: Dibutyl adipate) und / oder Butylenglycol-dicaprylat / dicaprat (INCI: Butylene Glycol Dicaprylate / Dicaprate).

The present disclosure relates to a pharmaceutical composition for topical administration, its preparation method, and use. Specifically, the present disclosure relates to a pharmaceutical composition containing an active ingredient, dimethyl sulfoxide, and a penetration enhancer, where the active ingredient is (3aR,5s,6aS)-N-(3-methoxy-1,2,4-thiadiazol-5-yl)-5-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxamide or a pharmaceutically acceptable salt thereof, and the penetration enhancer is one or more selected from lactic acid, isopropyl myristate, and propylene glycol monocaprylate. The pharmaceutical composition has good skin penetration properties, is stable, and is easily administered.

The invention provides a tea flower active ingredient scalp micro-ecological balance regulator and a preparation method thereof. The shampoo comprises water, sodium methyl cocoyl taurate, cocamidopropyl hydroxy sulfobetaine, octyl / decyl glucoside, sodium chloride, glycerol, phenoxyethanol, essence, PPG-3 octyl ether, cocoyl glutamic acid, sodium lauroamphoacetate, piroctone olamine salt, PEG-150 distearate, frankincense oil, panthenol, guar gum hydroxypropyl trimethyl ammonium chloride and a camellia extract. The preservative is prepared from citric acid, EDTA (Ethylene Diamine Tetraacetic Acid) disodium, benzoic acid, butanediol, tetrasodium glutamate diacetate, glycerol caprylate, dehydroacetic acid, sodium dehydroacetate, guava fruit extract and sodium surfactin. The preparation method comprises the following steps: uniformly mixing part of the components to obtain a mixed solution A, adding the camellia extract and other components, uniformly stirring to obtain a mixed solution B, and finally adding the essence, and uniformly stirring to obtain the regulator. The scalp micro-ecological balance can be adjusted, and the scalp environment can be improved.

The present invention provides a preservative for an external preparation for skin and a use thereof. The preservative comprises: hinokitiol; and one or more solvents selected from the group consisting of alkantriol having 3 to 6 carbon atoms, dipropylene glycol, glycerol caprylate, ethylhexylglycerin, and phenoxyethanol. According to one aspect of the present invention, the preservative for an external preparation for skin can be stably held in a liquid state at room temperature and under cold storage conditions, and can exhibit an excellent antibacterial effect after being formed into a dosage form.

The present application relates to a kind of degradable disulfide bond-containing peroxide ester initiator and its preparation degradable branched polymer application, belong to the field of functional initiator design.The present application uses tert-butyl (cumene) peroxide and thioctic acid as raw material, synthesizes the peroxide tert-butyl (cumene) thioctic acid ester containing ring-opening polymerizable disulfide bond as initiator, initiates vinyl monomer to carry out self-initiated radical polymerization reaction, and successfully obtains degradable branched polymer.Through adjusting the amount-of-substance ratio of initiator and polymer monomer, the branching degree of polymer is adjusted, the degradable disulfide bond-containing peroxide ester functional initiator is synthesized in the present application, under the initiator, under conventional radical polymerization conditions, without branched monomer, and successfully prepared degradable branched polymer.The reaction method is simple and easy to operate, and monomer conversion rate is high, the branching degree of polymer is controllable, and the branched polymer can be degraded, and the applicability of branched polymer for various types of monomers is strong.

The application discloses a method for synthesizing lipoic acid ester (I) by using buffer salt. The method takes 6,8-dichlorooctanoic acid ester (II) as raw material, adds buffer salt to stabilize the pH value of the reaction system in the process of ring closing reaction with a sulfuration reagent, thereby inhibiting the hydrolysis of lipoic acid ester, and improving the yield and purity of the product lipoic acid ester (I). The application is simple, convenient and practical, and is suitable for industrialized large-scale production of lipoic acid ester (I).

Long term storage stable fulvestrant-containing compositions are disclosed. The compositions can include fulvestrant; a solvent selected from dimethyl sulfoxide (DMSO), glycofurol, N-methyl pyrrolidone, and mixtures thereof; an oil mixture selected from a mixture of caprylic and capric triglycerides, a mixture of caprylic, capric and linoleic triglycerides, a mixture of caprylic, capric and succinic triglycerides, and a mixture of propylene glycol dicaprylate and propylene glycol dicaprate; and a sustained release member selected from benzyl benzoate, dihydrolipoic acid, benzyl alcohol and lipoic acid. The fulvestrant-containing compositions have less than about 5% total impurities, on a normalized peak area response (“PAR”) basis as determined by high performance liquid chromatography (“HPLC”) at a wavelength of 223 nm, after at least about 24 months of storage at a temperature of from about 5° C. to about 25° C.