The invention discloses a CBD Cannabis sativa anti-inflammatory whitening cream. The cream comprises the following raw material in parts by weight: water, ethylhexyl stearate, cetostearyl alcohol, glyceryl stearate, dibutyl adipate, glycerol, tocopheryl acetate, sodium ascorbyl phosphate, sorbitan stearate, polysorbate, wild soybean oil, phenoxyethanol, laureth-7 citrate, essence, lauryl glucoside, triethanolamine, polyglycerol-2 dipolyhydroxystearate, avocado butter, sodium hyaluronate, xanthan gum, beta-glucan, citric acid, an industrial hemp extract, vitamin E, jojoba seed oil, collagen, allantoin, ethylhexylglycerin, sunflower seeds and a calendula extract. According to the whitening cream, the industrial Cannabis sativa extract, the wild soybean oil and the calendula extract are addedinto the formula of the whitening cream, so that dryness and roughness of skin are relieved, the skin is moisturized and full, and the whitening cream is suitable for people with various skins and has a wide market prospect.