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Medical cold compress plaster and preparation method thereof

A technology of cold compress and gel layer, which is applied in the field of medical cold compress and its preparation, which can solve the problems of only cooling down, single function of cold compress, and failure to repair the skin, so as to resist various external stimuli, effectively Conducive to wound healing and prevent moisture evaporation

Inactive Publication Date: 2020-03-27
上海植帅生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Aiming at the problems existing in the prior art, the purpose of the present invention is to provide a medical cold compress and its preparation method, which solves the problem that the existing cold compress has a relatively single function, most of which only have the effect of cooling down, and the skin is damaged after the skin is broken. It cannot be used, it cannot repair the skin, and the effect is not obvious

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A medical cold compress, which consists of a backing layer, a gel layer and a covering layer connected sequentially from top to bottom. The shape of the medical cold compress is a special shape that conforms to the physiological curve of the site of use. The gel layer is composed of the following raw materials in weight percentage Prepared: epidermal growth factor 6%, ceramide 3%, hyaluronic acid 5%, accelerator 10%, ginger extract 3%, oat extract 5%, functional composition 4%, forsythia extract 5%, silk 3% plain protein solution, 0.8% auxiliary agent, and the balance is water.

[0034] Further, the epidermal growth factor is basic fibroblast growth factor (bFGF) or human epidermal growth factor (EGF) or a compound of the two, the molecular weight of bFGF is 8.5KDa~17.2KDa, and the biological activity is 5×105IU / mg , EGF molecule is 5.2KDa ~ 7.6KDa, biological activity 5 × 106IU / mg.

[0035] Further, the accelerator is borneol or a combination of borneol and allantoin,...

Embodiment 2

[0045] A medical cold compress, which consists of a backing layer, a gel layer and a covering layer connected sequentially from top to bottom. The shape of the medical cold compress is a special shape that conforms to the physiological curve of the site of use. The gel layer is composed of the following raw materials in weight percentage Prepared: epidermal growth factor 8%, ceramide 6%, hyaluronic acid 7.5%, accelerator 12.5%, ginger extract 6.5%, oat extract 7.5%, functional composition 5%, forsythia extract 6%, silk 4% plain protein solution, 1.1% auxiliary agent, and the balance is water.

[0046] Further, the epidermal growth factor is basic fibroblast growth factor (bFGF) or human epidermal growth factor (EGF) or a compound of the two, the molecular weight of bFGF is 8.5KDa~17.2KDa, and the biological activity is 5×105IU / mg , EGF molecule is 5.2KDa ~ 7.6KDa, biological activity 5 × 106IU / mg.

[0047] Further, the accelerator is borneol or a combination of borneol and al...

Embodiment 3

[0057] A medical cold compress, which consists of a backing layer, a gel layer and a covering layer connected sequentially from top to bottom. The shape of the medical cold compress is a special shape that conforms to the physiological curve of the site of use. The gel layer is composed of the following raw materials in weight percentage Prepared: epidermal growth factor 10%, ceramide 9%, hyaluronic acid 10%, accelerator 15%, ginger extract 10%, oat extract 10%, functional composition 6%, forsythia extract 7%, silk 5% plain protein solution, 1.4% auxiliary agent, and the balance is water.

[0058] Further, the epidermal growth factor is basic fibroblast growth factor (bFGF) or human epidermal growth factor (EGF) or a compound of the two, the molecular weight of bFGF is 8.5KDa~17.2KDa, and the biological activity is 5×105IU / mg , EGF molecule is 5.2KDa ~ 7.6KDa, biological activity 5 × 106IU / mg.

[0059] Further, the accelerator is borneol or a combination of borneol and allant...

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Abstract

The invention discloses a medical cold compress plaster and a preparation method thereof, and belongs to the field of cold compress plasters. The medical cold compress plaster comprises, from the topto the bottom, a back lining layer, a gel layer and a cover layer; and the medical cold compress plaster has an appearance of a special shape conforming to physiological curve of a site of use. The medical cold compress plaster adopts a nonwoven fabric with good air permeability as a base cloth; and the gel layer is coated on the nonwoven fabric. Being applied on the skin on the body surface for cold compress, the gel layer acts on the skin of the body so as to form a layer of breathable film protective layer on the skin surface of the body; and moreover, components of the gel layer and mass percentage of each of the components are optimized, so that the medical cold compress plaster is capable of better maintaining skin moisture, preventing evaporation of skin moisture on the body surface, resisting various external stimuli, relieving skin allergy, improving skin problems, such as pigmentation and the like, repairing epidermal tissue, restoring skin barrier functions and preventing microbial invasion on the skin surface. Therefore, the medical cold compress plaster is diversified in functions, and good in use effects.

Description

technical field [0001] The invention relates to the technical field of cold compresses, in particular to a medical cold compress and a preparation method thereof. Background technique [0002] Cold compress is a more economical cold compress therapy through physical cooling. Traditional cold compress methods mainly use ice water, ice cubes, alcohol, etc., but these methods have short cold compress time, large dosage, uneven cold compress effect, easy to cause local frostbite, and are inconvenient to carry and store. [0003] The cold compress is improved according to the traditional cold compress method. The TDDS new drug release system prepared on the basis of polymer gel is the core. It is composed of a backing layer, a gel layer and an anti-adhesive layer. The vaporization of water and natural cooling ingredients takes away the heat, which can achieve local cooling. The drug in it is combined with the hydrogel, and through hydration, the drug ingredients can quickly pene...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/70A61P29/00A61K8/02A61K8/73A61K8/64A61Q19/02A61Q19/00A61Q19/08
CPCA61K36/9068A61K36/634A61K9/7023A61K47/46A61P29/00A61K8/0208A61K8/735A61K8/736A61K8/64A61K8/73A61Q19/02A61Q19/00A61Q19/004A61Q19/08A61K2800/592A61K2300/00
Inventor 王焕连
Owner 上海植帅生物科技有限公司
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