163results about How to "Improves pigmentation" patented technology

Carotenoids are provided as dietary supplements to animal feed. These supplements improve the bioavailability of carotenoids by providing them in combination with phospholipids. The invention provides animal feeds for aquatic and terrestrial animals, and methods for making the feeds.

The present invention relates to skin care compositions, including cosmeceuticals, for topical application, and more particularly, a skin cream, comprising exosomes and cell culture medium conditioned by cells grown in two-dimensional culture. Also included are methods of making and using such compositions and kits comprising the skin cream therein.

Compositions, kits and methods are provided for conditioning, revitalizing, volumizing or increasing the natural pigmentation of the hair, including hair on the scalp, eyelashes, eyebrows, mustache and beard, promoting healthy growth, and treating and preventing loss, thinning or miniaturization of hair due to aging, various genetic, pathological, radiation, chemotherapy, chemical treatment environmental or other reasons.

The present invention relates to skin care compositions, including cosmeceuticals, for topical application, and more particularly, a skin cream, comprising exosomes and cell culture medium conditioned by cells grown in two-dimensional culture. Also included are methods of making and using such compositions and kits comprising the skin cream therein.

The invention relates to a preparation method for glabrous greenbrier rhizome extract. The method comprises the following steps of adding coarse powder into an organic solvent-aqueous solution, performing refluxing extraction, and performing standing, filtering and concentration to obtain glabrous greenbrier rhizome crude extract; dispersing the extract by using water, performing separation and purification by using a macroporous adsorption resin column, performing elution sequentially by using water, a 40 to 80 percent organic solvent-aqueous solution and an 85 to 95 percent organic solvent-aqueous solution, and concentrating and drying eluent of each part to obtain extract of each part, wherein the glabrous greenbrier rhizome extract is obtained by performing concentration and drying on the part eluted by water or the 40 to 80 percent organic solvent-aqueous solution, and is used for inhibiting the activity of tyrosinase and the synthesis of melanin, and a composition comprises 0.01 to 15 mass percent of glabrous greenbrier rhizome extract. The preparation method has the advantages that various whitening effect tests show that the glabrous greenbrier rhizome extract can be used for effectively inhibiting the activity of the tyrosinase and the synthesis of the melanin, can be used for an external skin product as an active whitening raw material, and is high in safety, and the effects of improving skin pigmentation and whitening skin can be achieved.

The invention relates to a propolis soft capsule. The propolis soft capsule comprises a rubber sheet and a capsule content, wherein the capsule content comprises the following components in percent by weight: 20%-60% of propolis supercritical CO2 extract, 30%-70% of wheat-germ oil and 1%-10% of vitamin E; components of the rubber sheet are gelatin, glycerol and purified water in a weight ratio of 100:42:100. The propolis soft capsule is integrated with improving effect of propolis on diabetes mellitus and preventing effect of vitamin E on chronic complication of the diabetes mellitus; moreover, the components are good in synergistic effect. The invention also provides a preparation method of the propolis soft capsule.

The invention discloses a composition containing L-Ergothioneine extract, brown rice fermentation filtrate and acetylchitosamine and application of the composition. The composition includes 0.1-2.0 parts of L-Ergothione extract, 0.1-4.0 parts of brown rice fermentation filtrate and 0.1-2.0 parts of acetylchitosamine. Since the three natural fermentation source components which include the L-Ergothioneine extract, brown rice fermentation filtrate and acetylchitosamine are selected, the composition has the advantages of naturalness, high activity, easy absorption and high safety, an obvious synergistic effect is achieved through sieving of the dosage of the components, meanwhile, the effects of regulating the biological rhythm of skin, delaying skin aging and improving pigmentation are achieved, and damage of blue light to the skin is prevented from the three aspects, so that comprehensiveness is achieved, and the blue light resistant effect is achieved.

A process for photomorphogenically enhancing plants is presented wherein a natural or artificial light source emits light through a transmittive material. The material is optionally borosilicate glass with a steep edge situation at or near 280 nm so as to selectively filter out light in the UVC or low UVB regions. The glass allows high transmissibility such that as much as 98% of all light at or above the edge situation passes thorough the material. The percent transmission and edge situation may be defined by glass thickness or by combining multiple types of glass. The light is then contacted with a plant whereby a photomorphogenic response is elicited.

The invention provides mesenchymal stem cell injection liquid and a preparation method, which aim to solve the problem of how to use a mesenchymal stem cell to efficiently repair and improve damaged skin and fundamentally delay and stop skin cell aging. The injection liquid provided by the invention is prepared from the mesenchymal stem cell, DMSO, EGF, glutathione, vitamin C, human serum albumin,a ginkgo biloba extract and a menstruum. The mesenchymal stem cell is obtained through carrying out hungry culture on P2 to P5-generation mesenchymal stem cells and stimulating through an epidermal growth factor. The obtained mesenchymal stem cell has a good differentiative capacity and a good proliferation capacity, has a better differentiation potential, and is synergized with the DMSO, the EGF, the glutathione, the vitamin C, the human serum albumin and the ginkgo biloba extract, so that skin wrinkles and hyperpigmentation can be remarkably reduced.

The invention relates to natural traditional Chinese medicine mask powder as well as a preparation method and a mask thereof. The natural traditional Chinese medicine mask powder is prepared from the following raw materials in parts by weight: 7-23 parts of angelica sinensis, 3-14 parts of radix angelicae, 3-13 parts of radix paeoniae alba, 17-33 parts of bighead atractylodes rhizome, 3-20 parts of common bletilla tuber, and 3-15 parts of white poria. The raw materials also can be further added as follows: 12-28 parts of tribulus terrestris, 1-8 parts of liquorice and 1-8 parts of pearl powder. By cleaning and baking the specific parts of angelica sinensis, radix angelicae, radix paeoniae alba, bighead atractylodes rhizome, common bletilla tuber and white poria, and further added tribulus terrestris, liquorice and pearl powder and grinding into powder, so that a natural traditional Chinese medicine mask is obtained. The natural traditional Chinese medicine mask powder can be further mixed with water or egg white so as to be blended into a paste mask for a user to use. The components are in synergistic interaction, the natural traditional Chinese medicine mask powder is applicable to all types of skin, and is used for improving various skin problems such as acnes, chromatosis and wrinkles, and the product is free of other added ingredients.

The invention provides an acne-removing cosmetic composition mainly using natural plant raw materials and a preparation method. In percentage by mass, the composition is prepared from 3.81 to 70.1% of composite active ingredients and 29.9 to 96.19% of cosmetic additive. The composition provided by the invention contains the composite active ingredients natural in source, has a rapid and obvious acne removing effect, and also can comprehensively nurse acne skin; any skin irritation and side effects are not found; the acne-removing cosmetic composition is suitable for being used for a long time; metabolism of the skin can be promoted; the skin microstate can be improved; the comprehensive condition of the skin is comprehensively improved; the resisting ability of the skin per se is enhanced; regeneration of acne is effectively prevented.

Topically applicable skin depigmenting compositions, suited for treatment of such hyperpigmentary disorders as melasma and chloasma, contain a thus effective amount of at least one skin depigmenting active agent, for example hydroquinone or 4-hydroxyanisole, in admixture with a depigmentation-accelerating amount of adapalene (6-[3-(1-adamantyl)-4-methoxyphenyl]-2-napthanoic acid), and optionally with at least one sunscreen, formulated into a topically applicable, physiologically acceptable medium therefor.

The invention relates to a hand cream made of Chinese medicinal compositions and a method for preparing the same, the preparation of the hand cream consists of angelica sinensis, ginseng codonopsis pilosula, astragalus, ligusticum wallichii and bletilla striata, and after the extraction by a suitable solvent and the adding of a cream substrate, the hand cream is manufactured. The hand cream has functions of moistening hands and restoring rhagades.

The invention discloses a Tibetan medicinal extract skin-care product and a preparation method thereof. The skin-care product comprises the following raw materials in percentage by weight: 7-10% of gentiana macrophylla extract, 3-5% of sapodilla extract and 3-5% of senecio cineraria extract. The skin-care product comprises facial cleanser, essence and emulsion. The main raw materials are Tibetan medicaments, so the skin-care effect is good and the value of the Tibetan medicament can be sufficiently utilized.

The present disclosure provides compositions and methods for biologically producing isoprene using methanotrophic bacteria that utilize carbon feedstock, such as methane or natural gas.

The invention discloses a skin-whitening antioxidant composition. The skin-whitening antioxidant composition comprises, by weight, 1-50 parts of collagen peptide-zinc chelate, 1-50 parts of marine fish oligopeptide, 1-5 parts of haematococcus pluvialis extract, 1-10 parts of epigallocatechin gallate, 0.1-5 parts of lycopene, 0.1-5 parts of lycium ruthenicum and 0.1-5 parts of hyriopsis cumingii polysacchride. The invention further discloses application of the skin-whitening antioxidant composition. The skin-whitening antioxidation composition can replenish collagen in the skin dermis, preventthe damage of ultraviolet light to the skin tissue and inhibit the activity of tyrosinase, and effectively relieve the common skin problems of skin dullness, pigmentation, skin sagging and the like.

Methods are provided for modulating pigmentation and melanin production by administering an extract of Polygonum multiflorum Thunb (PMT). Methods are also provided for treating conditions that may be regulated or associated with abnormal melanogenesis.

The invention relates to the technical field of plant active material extraction, and particularly relates to a vitex negundo linn leaf extract and preparation method as well as application thereof. General flavone content in the vitex negundo linn leaf extract is not less than 82.5%, organic is not used in the preparation method of the vitex negundo linn leaf extract, and on the premise of guaranteeing purity of flavonoid compounds, extraction efficiency is improved. Experiment shows that, when being used in skin care products, the vitex negundo linn leaf extract cannot cause adverse reaction, and enables skin to be more shiny and elastic.

The invention discloses a compound essential oil for whitening skin and removing skin wrinkles and relates to cosmetics and a medical appliance, in particular to a compound essential oil for whitening skin and removing skin wrinkles. The compound essential oil comprises the following raw materials in percentage by weight: 30-55 percent of rosemary essential oil, 20-35 percent of tea tree essential oil, 35-55 percent of orange flower essential oil, 25-35 percent of pogostemon cablin essential oil, 25-45 percent of geranium essential oil and 1,000 percent of caper euphorbia seed essential oil. The compound essential oil for whitening skin and removing skin wrinkles of the invention is prepared by adopting the steps of mixing and stirring the raw materials according to the proportion prescription and then standing. The invention can rapidly and thoroughly whitening skin and restore skin elasticity and achieves the effects of whitening skin and removing skin wrinkles.

The invention discloses an early anti-aging and brightening nutrient containing a melaleuca bracteate extract. The early anti-aging and brightening nutrient comprises the following components in partsby weight: 1-10 parts of polyol, 1-10 parts of a moisturizer, 2-20 parts of an emollient, 1-5 parts of an emulsifier, 0.1-2 parts of a thickener, 0.1-2 parts of a pH regulator, 0.1-5 parts of an antioxidant, 0.1-10 parts of a skin conditioner and 80-100 parts of deionized water, wherein the skin conditioner contains the melaleuca bracteate extract. According to the early anti-aging and brightening nutrient, the melaleuca bracteate extract is added to various assistants, so that skin photoaging is effectively prevented, balance of melanocytes is restored, natural color and luster of skin are restored, wrinkles are significantly reduced and the elasticity of the skin is increased.

Peptides that increase melanin synthesis are provided. These peptides include pentapeptides YSSWY, YRSRK, and their variants. The peptides may activate the enzymatic activity of tyrosinase to increase melanin synthesis. The pharmaceutical, cosmetic, and other compositions including the peptides are also provided. The methods of increasing melanin production in epidermis of a subject are provided where the methods include administering compositions comprising an amount of one or more peptides effective to increase the melanin production. The methods also include treating vitiligo or other hypopigmentation disorders with compositions including one or more peptides.

The invention provides application of leaf mustard polypeptide to preparation of skin whitening and repair cosmetics. The leaf mustard polypeptide has small molecular weight, can be easily absorbed by the skin and can aim at the problem of pigmentation in the skin damage repair process when being used for preparing the cosmetics; the acceleration of the skin damage repair process is promoted; the skin cell growth differentiation is accelerated; the repair time is shortened; the skin is protected, so that the hyperpigmentation of the skin caused by protection reactivity is relieved.

The present disclosure provides methods of increasing skin pigmentation in a subject in need thereof using salt-inducible kinase (SIK) inhibitors, such as macrocyclic compounds of Formula (I), bicyclic urea compounds of Formula (II), (III), and (IV), and compounds of Formula (V), (VI), (VI-A), or (VII). Also provided are pharmaceutical compositions, methods, and uses that include or involve a compound described herein.

The invention belongs to the field of medical supplies, and particularly relates to a medical cold compress patch. The medical cold compress patch comprises a backing layer, a gel layer and a coveringlayer, wherein the backing layer is a non-woven fabric, the covering layer is a polyethylene film, and the gel layer is prepared from polyvinyl alcohol, a skin moistening agent, an accelerant and purified water; the skin moistening agent is prepared from a moisturizing agent and an auxiliary agent; the moisturizing agent is prepared from glycerol and trehalose; the auxiliary agent is selected from one or more of sodium chloride, sodium hyaluronate and ceramide; the accelerant is borneol or a combination of borneol and allantoin. The invention also provides a preparation method of the medicalcold compress patch. The medical cold compress patch provided by the invention can maintain the skin moisture, prevent evaporation of skin moisture of the body surface, resist various external stimulations, relieve skin allergy, alleviate hyperpigmentation and other skin problems, and can prevent the invasion of microorganisms on the skin surface.

Carotenoids are provided as dietary supplements to animal feed. These supplements improve the bioavailability of carotenoids by providing them in combination with phospholipids. The invention provides animal feeds for aquatic and terrestrial animals, and methods for making the feeds.

The present invention relates to a graft wherein cultured autologous melanocytes are delivered using a biopolymer. The present invention describes the composition, method of preparation and its properties relating to safety and efficacy. The graft of the present invention has a potential use in treating hyper- and hypopigmentation disorders.

The invention discloses natto powder and a production method thereof and a whitening and freckle-removing nutrient composition containing the natto powder. The production method has the advantages that production water is replaced by fruit juice rich in anthocyanin during natto fermentation, and the produced natto powder has the function of traditional natto powder, is rich in anthocyanin and freeof beany flavor, has fruit fragrance and has the sour and sweet taste of fruits; meanwhile the production method is mild in preparation conditions, anthocyanin is less prone to denaturation and inactivation during fermentation, and the produced natto powder can well retain the original structure of the anthocyanin. The whitening and freckle-removing nutrient composition is compounded by the nattopowder, oligopeptide powder, probiotics and vitamin C and is capable of improving skin problems from inside to outside from multiple aspects such as oxidation resisting, collagen supplementing and internal environment improving, capable of fundamentally improving common skin problems such as deep yellowness, darkness, stains and brown stains and capable of maintaining the smoothness and tenderness of the skin.

The present invention relates to polypeptide compounds that are modulators (e.g., agonists and antagonists) of the melanocortin-4 receptor (MC4R) and pharmaceutical compositions comprising same. The compounds described herein are polypeptide of the following structural Formula (I):or a pharmaceutically acceptable salt thereof. Values and preferred values of the variables in structural Formula (I) are described herein.

The invention relates to a Chinese medicinal herb freckle-removing cream which takes natural Chinese medicinal herbs as main components and is prepared by adopting a solvent extraction method. The Chinese medicinal herb freckle-removing cream comprises the following components: ginseng, glycerol, radix salviae miltiorrhizae, arbutin, evening primrose seed essences, green tea powder and amla extractives. The Chinese medicinal herb freckle-removing cream disclosed by the invention has the effects of enhancing skin immunity, resisting bacteria, removing freckles, resisting free radicals, whitening skin, weakening pigments, resisting oxidation and improving pigmentation and pachylosis, has no side effect after being used. A user can smear a right amount of the cream on freckles after cleaning and toning the skin in the morning and evening and the user can massage the skin to promote the absorption of the cream.

A feed additive with high antibacterial efficiency and high effect to promote growth for domestic animals and fowls is prepared from superfine arsanilic acid, calcium phosphate and sodium sulfate.