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2results about How to "Improves pigmentation" patented technology

Camellia sinensis flower whitening extract, preparation method and application thereof

PendingCN122499073Aavoid safety hazardsIn line with the concept of green chemistry
This invention relates to a whitening extract from Camellia yunnanensis, its preparation method, and its applications, belonging to the field of plant extract preparation and cosmetic technology. The extraction method includes: preparing a eutectic solvent by mixing choline chloride and citric acid in a molar ratio of 1:1 to 1:5, and adjusting the water content to 40%–80%; mixing Camellia yunnanensis raw material powder with the eutectic solvent at a material-to-liquid ratio of 1:10–30 (g / mL), and performing ultrasound-assisted extraction. This extract can be used to prepare cosmetics or topical skin preparations with whitening, brightening, antioxidant, or pigmentation-improving effects, as well as tyrosinase activity inhibitors and α-amylase activity inhibitors. This invention provides a green and efficient method for extracting the whitening active ingredients from Camellia yunnanensis.
Owner:YUNNAN UNIVERSITY OF CHINESE MEDICINE

A multi-layered osmotic controlled-release acid formulation and a method for preparing the same

PendingCN122251284AChange instant release characteristicsless irritatingCosmetic preparationsToilet preparationsActive agentSalicylic acid
The application provides a multi-layer penetration controlled-release acid preparation and a preparation method thereof, and belongs to the field of cosmetics. The preparation is composed of Aspergillus oryzae fermentation substrate freeze-dried powder, composite alpha-hydroxy acid, salicylic acid, poloxamer 407, polyhydric alcohol and non-ionic surfactant. The freeze-dried powder is obtained by co-fermenting olea europaea leaves and curcuma and refining through ultrafiltration. A temperature-sensitive phase change system is constructed by using poloxamer, so that the product is changed from a liquid state to a gel state at body temperature, and the synergistic controlled release of acid components and bioactive substances is realized. The preparation process adopts low-temperature swelling and vacuum freeze-drying technology, so that the stability of the system and the efficiency of the active substances are ensured. The application significantly reduces the irritation of high-concentration acid, improves the black suppression and repair effect, and is suitable for precise improvement of hyperpigmentation problems such as chloasma.
Owner:THE FIRST HOSPITAL OF HEBEI MEDICAL UNIV +1