Traditional Chinese medicine composition for treating diarrhea-type irritable bowel syndrome

Abstract

The invention discloses a traditional Chinese medicine composition for treating diarrhea-type irritable bowel syndrome. The traditional Chinese medicine composition comprises the following components,by weight: 15 to 25 parts of radix pseudostellariae, 5 to 15 parts of rhizoma atractylodis macrocephalae, 15 to 25 parts of poria cocos, 3 to 10 parts of honey-fried licorice root, 5 to 15 parts of the root of fangfeng, 10 to 20 parts of white paeony root, 3 to 10 parts of steamed dried tangerine or orange peel, 3 to 10 parts of the rhizome slices of Chinese goldthread and 5 to 15 parts of commonaucklandia root. The traditional Chinese medicine composition is proved to have an obvious analgesic effect on physical pain and chemical pain and can play an antidiarrheal role in inhibiting intestinal motility; the intestinal hypersensitivity state can be improved obviously; the moisture content of excrement can be reduced; the mucous membrane barrier function can be enhanced; and the intestinal flora can be improved. The traditional Chinese medicine formula which is safe, effective, free of drug dependence, mild and easy to take can be provided for diarrhea-type irritable bowel patients; and the traditional Chinese medicine formula has important medical values for improving the clinical cure rate of IBS-D, relieving clinical symptoms and standardizing and managing diseases.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine and relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating diarrhea-type irritable bowel syndrome. Background technique [0002] Irritable bowel syndrome (IBS) is a common functional intestinal disorder characterized by recurrent abdominal pain, changes in stool properties or defecation habits, and no organic changes in the intestinal tract. Group of clinical syndromes. According to the Rome IV criteria, IBS can be divided into three subtypes according to the stool characteristics: irritable bowel syndrome with diarrhea (irritabel bowel syndrome with predominant diarrhea, IBS-D), constipation (irritabel bowel syndrome with diarrhea). predominant constipation (IBS-C), mixed type (irritabel bowel syndrome with mixed bowel habits, IBS-M); among them, diarrhea-predominant irritable bowel syndrome accounts for the larg...

AI Technical Summary

Problems solved by technology

Due to the complex pathogenic factors and the lack of good clinical biological diagnostic markers, there are multiple, overlapping, and non-specific symptoms, which have brought certain difficulties to diagnosis and treatment.

[0005] The current clinically used Western medicines include antidiarrheals, serotonin drugs, antispasmodics, antidepressants, microecological regulators, etc., and their curative effects are not ideal, and long-term use has obvious toxic and side effects, and patients often cannot tolerate them, leading to illness. Repeatedly, some patients can't even maintain clinical remission; a published medicinal composition for the treatment of irritable bowel syndrome includes clove, cinnamon composition, selective gastrointestinal antagonists and other drugs

This category belongs to the synthetic medicine of traditional Chinese and Western medicine, which is synthesized by Chinese medicine extract and Western medicine. unclear

[0006] On the other hand, traditional Chinese medicine formulas for the treatment of irritable bowel syndrome are mostly based on Bupleurum Shugan San, Tongxie Yao Fang, Shenling Baizhu San, etc. Regional characteristics increase or decrease drugs, and the curative effect of most published traditional Chinese medicine formulas is only verified by clinical research or animal experiments. Published traditional Chinese medicine prescriptions have shortcomings such as vague scope of application and unclear curative effect mechanism

And the published traditional Chinese medicine formula rarely reports the influence of traditional Chinese medicine on the intestinal microbial structure of patients with irritable bowel syndrome

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