Absorbable implant material composed of magnesium or magnesium alloy containing doped nanodiamonds

A technology of nano-diamond and implant materials, which is applied in the field of implant materials and its manufacturing, and can solve problems such as high cost and complicated inspection

Inactive Publication Date: 2020-04-17
HELMHOLTZ ZENT GEESTHACHT ZENT FUER MATERIAL UND KUESTENFORSCHUNG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Such inspections are relatively complex and costly

Method used

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Embodiment Construction

[0010] Fe-doped nanodiamonds (Fe-ND), for example, have been published as protein markers, see B.-R. Lin et al. "Fe Doped Magnetic Nanodiamonds Made by Ion Implantation as Contrast Agent for MRI" Scientific Reports (2018) 8:7058. So far, Fe-doped nanodiamonds have been used to study the visualization of biological cell processes. Fe-doped nanodiamonds are harmless to biology and can be used as a contrast agent to make biological processes visible.

[0011] For the production of Fe-doped nanodiamonds, we call "Fe-doped magnetic nanodiamonds prepared by ion implantation as a contrast agent for MRI". Nanodiamonds are well known and can be purchased from Sigma-Aldrich, for example. Fe ions can be easily implanted in the nanodiamond. To this end, the nanodiamonds are preferably suspended in demineralized water, and then the suspension is applied to the silicon wafer. Then Fe ions can be injected into the nanodiamond by sputtering. In this method, it is preferable to use an energy...

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Abstract

The present invention relates to an absorbable implant material composed of magnesium or a magnesium alloy and to a method for the production thereof. A disadvantage of the known absorbable implants is that the position of the implant during the medical implantation procedure and immediately thereafter can only be tracked by means of X-ray examinations. According to the invention, the absorbable implant material comprising homogeneously distributed Fe-doped nanodiamonds in a matrix composed of magnesium or the magnesium alloy, is provided. The Fe-doped nanodiamonds are harmless to organisms soas to allow the detection of the implant material in the blood plasma of the patient by means of magnetic resonance imaging. According to the invention, the absorbable implant material according to the invention is produced by a method in which the magnesium or the magnesium alloy is melted, the Fe-doped nanodiamonds are added to a melt, and the melt composed of the magnesium or the magnesium alloy that has been provided with Fe-doped nanodiamonds is subjected to an ultrasound treatment.

Description

Technical field [0001] The invention relates to an implant material composed of magnesium or magnesium alloy and a manufacturing method thereof. Background technique [0002] At present, metal implants composed of medical grade steel or titanium are used in veterinary medicine and human medicine to treat weight-bearing long bone fractures. However, in terms of its mechanical properties, this implant is harder than bone, which may cause stress shielding. For these and other reasons, related implants are usually removed after their function is completed, which can burden the patient due to the required anesthesia and re-tissue trauma. [0003] The use of absorbable implants for the treatment of fractures has received increasing attention. The goal is that as the strength of the healing bone increases, the implant undergoes stress adjustment through a slow decrease in its stability. The absorbable implants used so far are composed of different polymers, which cannot perform optimal...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C22C23/00C22C26/00C22C1/10C22C1/02A61L27/42A61L27/58
CPCA61L27/427A61L27/58A61L2430/02C22C1/1036C22C23/00C22C26/00A61L27/047A61L27/50A61L31/022A61L31/18A61L31/024A61L31/124A61L31/148B01J19/10
Inventor 哈乔·迪仁格
Owner HELMHOLTZ ZENT GEESTHACHT ZENT FUER MATERIAL UND KUESTENFORSCHUNG
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