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Whitening mask and preparation method thereof

A technology of whitening mask and phloretin, which is applied in the direction of pharmaceutical formulations, cosmetic preparations, dressing preparations, etc. It can solve the problems of poor water solubility, affecting bioavailability and application, etc., to repair damaged skin and restore natural health state, the effect of promoting the proliferation of newborn cells

Inactive Publication Date: 2020-05-05
广州古泉生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although phloretin has strong physiological activity, it is a planar molecule with relatively tight molecular packing, strong attraction between molecules due to hydrogen bonds, and poor water solubility (the solubility of phloretin in water is only 21.34 μg / mL). Thus greatly affecting its bioavailability and application

Method used

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  • Whitening mask and preparation method thereof
  • Whitening mask and preparation method thereof
  • Whitening mask and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The making of embodiment 1 facial mask 1

[0030] 1). 80 parts of water, 3 parts of tricaprylic capric glyceride, 8 parts of PEG-400, 3 parts of Plantern2000, 10 parts of glycerin, 10 parts of propylene glycol, 0.8 parts of laureth-23, 6 parts of hydroxyethyl acrylate Ester, 8 parts of xanthan gum, 6 parts of allantoin and 10 parts of Tween-80 are added to the emulsification tank, and the stirring is started. Add 2 parts of hyaluronic acid into the emulsification tank while stirring to obtain the first pretreatment solution.

[0031] 2). Wrap 60 parts of water, 2 parts of vitamin E, 3 parts of vitamin C, 5 parts of hexapeptide-10, 3 parts of phloretin, 5 parts of glycosylated phloretin, and 2 parts of carnosine in hyaluronic acid- g-polyε-caprolactone derivative carrier nanomicelle to obtain the second treatment solution.

[0032] 3). Mix the first pretreatment liquid, the second pretreatment liquid and essence evenly.

Embodiment 2

[0033] Embodiment 2 Mask making 2

[0034] 1). 100 parts of water, 4 parts of tricaprylic capric glyceride, 7 parts of PEG-400, 4 parts of Plantern2000, 15 parts of glycerin, 10 parts of propylene glycol, 3 parts of laureth-23, 8 parts of hydroxyethyl acrylate Ester, 5 parts of xanthan gum, 10 parts of allantoin and 15 parts of Tween-80 are added to the emulsification tank, and the stirring is started. After the stirring is uniform, the temperature is slowly raised to 45 ° C. Add 3 parts of hyaluronic acid into the emulsification tank while stirring to obtain the first pretreatment solution.

[0035] 2). Wrap 80 parts of water, 2 parts of vitamin E, 0.5 part of vitamin C, 7 parts of hexapeptide-10, 1 part of phloretin, 10 parts of glycosylated phloretin, and 3 parts of carnosine in hyaluronic acid- g-polyε-caprolactone derivative carrier nanomicelle to obtain the second treatment solution.

[0036] 3). Mix the first pretreatment liquid, the second pretreatment liquid and ess...

Embodiment 3

[0037] Example 3 Clinically evaluates the whitening effect of Example 1

[0038] Select 30 healthy women aged 23-50 and divide them into experimental group and sample group, with 15 people in each group. The pigment content of their cheeks and skin color were measured, and then the test cosmetics were distributed. The subjects used the whitening mask continuously. The experimental group used it once a day in the evening, and applied it after cleansing. Other whitening cosmetics were discontinued during the experiment. After continuous use for 7d, 14d, 21d, and 30d, measure each efficacy index. At the same time, ask the volunteers how they feel after using the test samples and whether they have allergies, etc., and record their own comparisons before and after. 1d before using the cosmetics and 7d, 14d, 21d, and 30d after using the cosmetics, the changes in skin color were measured with a Lab colorimetric system spectrophotometer, and the test was performed 3 times continuo...

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Abstract

The invention discloses whitening mask and a preparation method thereof. The preparation method of the whitening mask comprises the following steps: performing pretreatment on water, a humectant, a film forming agent, a whitening agent, a skin moisturizing agent and the like so as to obtain a solution subjected to the pretreatment; adding the solution subjected to the pretreatment into an emulsification pot while carrying out heating at room temperature until the solution is heated to 60-65 DEG C; and then, adding vitamin E and a flavoring agent, and carrying out uniform stirring so as to formthe whitening mask. The whitening mask is prepared by adding whitening components, namely phloretin and glycosylated phloretin, in cooperation with basic raw materials, so that the prepared whiteningmask is capable of penetrating into the muscle base to remove melanin and free radicals so as to restore the skin's natural white state; and moreover, the whitening component, namely the phloretin, in the whitening mask has a natural preservation effect, so that the effect of preservation can be achieve without addition of a preservative.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a whitening mask and a preparation method thereof. Background technique [0002] The basal layer cells of the human epidermis contain 4% to 5% pigment cells. The color of human skin does not depend on the number of melanocytes, but on the number, size, distribution and degree of melanization of melanosomes. Therefore, some whitening ingredients achieve the whitening effect by affecting the formation, maturation and transfer of melanosomes. [0003] The scientific name of Phloretin is 2,4,6-trihydroxy-3-(4-hydroxyphenyl)propiophenone, which is a flavonoid compound with a dihydrochalcone structure. Phloretin is mainly distributed in plant species such as apples and pears in the form of its glycoside (phloridin), and its content is relatively high in the roots and trunk epidermis of fruit trees such as apples and pears, and is a characteristic phenolic substance of plant species such as a...

Claims

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Application Information

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IPC IPC(8): A61K8/35A61K8/60A61K8/64A61K8/73A61K8/85A61K8/02A61K8/06A61K8/92A61Q19/02A61Q17/00A61Q19/10
CPCA61K8/0291A61K8/068A61K8/35A61K8/602A61K8/64A61K8/735A61K8/85A61K8/922A61K2800/524A61K2800/592A61K2800/5922A61Q17/005A61Q19/02A61Q19/10
Inventor 范泽浩貌惠玲
Owner 广州古泉生物科技有限公司
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