Carcino-embryonic antigen detection method based on Fe2O3 material single-layer photoelectrochemical sensor

A carcinoembryonic antigen, photoelectrochemical technology, which is applied in the direction of chemical reaction of materials for analysis, scientific instruments, analysis materials, etc. Low problems, to achieve the effect of facilitating early diagnosis and disease monitoring, low detection limit, and high selectivity

Pending Publication Date: 2020-06-19
DONGGUAN UNIV OF TECH
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  • Abstract
  • Description
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Problems solved by technology

[0003] The defects in the above detection methods include: 1. The excitation source and the detection signal are the same, both are electrical (optical) signals
2. The input of a larger sample volume is required
3. Need to use large and complex instruments and equipment
4. Long time period
[0006] However, the photoelectrochemical method used to detect the concentrat

Method used

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  • Carcino-embryonic antigen detection method based on Fe2O3 material single-layer photoelectrochemical sensor
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  • Carcino-embryonic antigen detection method based on Fe2O3 material single-layer photoelectrochemical sensor

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Embodiment Construction

[0025] The present invention will be further described below in conjunction with the accompanying drawings.

[0026] Based on Fe 2 o 3 The carcinoembryonic antigen detection method of the material single-layer photoelectrochemical sensor comprises the following steps, a. preparing a modified αFe2O3 photoelectric material, b. taking the modified αFe2O3 photoelectric material in step a and assembling a detection electrode system, c. adopting the method in step b An electrode system was assembled for the quantitative detection of carcinoembryonic antigen.

[0027] Such as figure 1 Shown is a schematic diagram of electron flow in the detection process of the present invention.

[0028] From figure 1 It can be seen that in the single-layer unmarked photoelectric immunosensor, the transfer process of electrons from the electron donor in the solution to the photoelectric material (or from the photoelectric material to the electron acceptor) is affected by the steric hindrance eff...

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Abstract

The invention relates to the field of carcino-embryonic antigen detection, in particular to a carcino-embryonic antigen detection method based on a Fe2O3 material single-layer photoelectrochemical sensor. The method comprises the following steps: a, preparing a modified alphaFe2O3 photoelectric material, b, assembling the modified alphaFe2O3 photoelectric material in the step a into a detection electrode system, and c, quantitatively detecting the carcino-embryonic antigen by adopting the assembled electrode system in the step b. The method has the advantages of high sensitivity, high selectivity and low detection limit, and is beneficial to early diagnosis and disease monitoring of malignant tumors.

Description

technical field [0001] The invention relates to the field of carcinoembryonic antigen detection, in particular to a carcinoembryonic antigen detection method based on Fe2O3 material single-layer photoelectrochemical sensor. Background technique [0002] At present, the commonly used traditional methods for the detection of tumor markers include enzyme-linked immunosorbent assay (ELISA), electrochemiluminescence (ECL), fluorescent immunoassay (IFA), mass spectrometry and other immunoassay methods. [0003] The defects in the above detection methods include: 1. The excitation source and the detection signal are the same, both being electrical (optical) signals. 2. The input of larger sample volume is required. 3. Large and complex instruments and equipment are required. 4. The time period is long. [0004] Carcinoembryonic antigen (CEA), an acidic glycoprotein with the characteristics of human embryonic antigen, exists on the surface of cancer cells differentiated from endo...

Claims

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Application Information

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IPC IPC(8): G01N27/327G01N21/76G01N33/543
CPCG01N27/3275G01N21/76G01N33/5438G01N33/54393G01N21/69
Inventor 张敏谢永泽程发良宾倩韵谢世磊吕维忠
Owner DONGGUAN UNIV OF TECH
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