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Pharmaceutical composition for improving sleep comprising rare ginsenosides rg6 and f4

A ginsenoside, a technology for improving sleep, applied in the field of biomedicine

Active Publication Date: 2021-05-07
SHAANXI GIANT BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ginsenosides Rg6 and F4 are produced by deglycosylation and dehydration of saponins Rg1 and Re of the triol group. At present, they are mainly used for the treatment of non-small cell lung cancer, antithrombotic, cerebral infarction, central retinal vein occlusion and other diseases. No report on sleep quality

Method used

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  • Pharmaceutical composition for improving sleep comprising rare ginsenosides rg6 and f4
  • Pharmaceutical composition for improving sleep comprising rare ginsenosides rg6 and f4
  • Pharmaceutical composition for improving sleep comprising rare ginsenosides rg6 and f4

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] This embodiment provides a sleep-improving capsule, which is prepared by mass from the following raw materials: 500g of stachyose and 100g of starch are mixed evenly, passed through a 60-80 mesh sieve, and used for later use. According to the corresponding proportion, ginsenoside Rg6 is added 25g, ginsenoside F4 25g, vitamin 1g, trace element iron 0.5g, mixed evenly, wet granulated with 80% ethanol, passed through a 20-80 mesh sieve, dried, granulated with a 20 mesh sieve, filled into capsules, packed in each capsule Amount 300mg.

Embodiment 2

[0060] This embodiment provides a sleep-improving tablet, which is prepared by mass from the following raw materials: 600g of stachyose and 100g of starch are mixed evenly, passed through a 60-80 mesh sieve, and used for later use. According to the corresponding proportion, ginsenoside Rg6 is added 28g, 14g of ginsenoside F4, 0.8g of vitamins, 0.5g of trace element iron, mixed evenly, wet granulated with 80% ethanol, passed through a 20-80 mesh sieve, dried, granulated with a 20 mesh sieve, pressed into tablets, each tablet weighs 800mg .

Embodiment 3

[0062] This example provides a sleep-improving tablet, which is prepared by mass from the following raw materials: 400g of stachyose and 100g of starch are mixed evenly, passed through a 60-80 mesh sieve, and used for later use. According to the corresponding proportion, ginsenoside Rg6 is added 20g, 30g of ginsenoside F4, 2g of vitamins, 0.3g of trace element iron, mixed evenly, wet granulated with 80% ethanol, passed through a 20-80 mesh sieve, dried, granulated with a 20 mesh sieve, pressed into tablets, each tablet weighs 800mg .

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PUM

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Abstract

The invention relates to a medicinal composition for improving sleep comprising rare ginsenosides Rg6 and F4. The pharmaceutical composition of the present invention comprises ginsenoside Rg6 and ginsenoside F4 in an effective amount for improving sleep as active ingredients, and a pharmaceutically acceptable carrier. In the pharmaceutical composition, the weight ratio of ginsenoside Rg6 to ginsenoside F4 is 1:1~3:1. According to the present invention, a pharmaceutical composition of rare ginsenosides comprising rare ginsenosides Rg6 and F4, synergistic and having a sleep-promoting effect can be provided.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a rare ginsenoside Rg6 / F4 composition with sleep-promoting activity and synergistic effects. Background technique [0002] According to the statistics of the World Health Organization (WHO), 27% of people in the world have sleep problems, that is, at least 1 out of every 4 people "sleep well". According to the latest China sleep data report, from 2013 to 2018, the average sleep duration in China has dropped from 8.8 hours to 6.5 hours, waking up 1.8 times at night, and an average of 38.2% of Chinese people have sleep problems, which is higher than the global average. The value is 11.2% higher. Decreased sleep quality will not only affect the quality of work during the day, but also affect blood pressure, blood sugar, endocrine and immune functions, memory loss, dizziness, and drowsiness while driving. Long-term sleep can also cause negative emotions such as irritability, irritability...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/704A61K45/06A61K33/26A61P25/20
CPCA61K31/704A61K45/06A61K33/26A61P25/20A61K2300/00
Inventor 范代娣黄蓉段志广马晓轩
Owner SHAANXI GIANT BIOTECHNOLOGY CO LTD
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