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Immunochromatographic test device

An immunochromatography and testing device technology, applied in measurement devices, analytical materials, instruments, etc., can solve problems such as inability to obtain test results, and achieve the effect of accurate results

Inactive Publication Date: 2020-07-31
SEKISUI MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, when a sample is dripped into a test device in a clinical laboratory, accurate test results may not be obtained if an excessive amount of sample is injected into the test device due to a wrong operation by the operator in charge of the test

Method used

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  • Immunochromatographic test device
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0127] Figure 7 A and Figure 7 B shows the configuration of a modified embodiment of the device according to the invention, wherein additional protrusions are arranged for controlling the flow of excess sample.

[0128] Figure 7 A shows the case where additional protrusions 114 and 115 are provided for the lower case 100, and Figure 7 B shows the case where the upper case 200 is provided with an additional protrusion 215 . The protrusions 114, 115, 215 are liquid directing structures for preventing sample leaking from the sample pad from contacting the test strip. The height of such secondary confinement structures is lower than that of the support bases and protrusions 209, 210 so that those structures do not directly contact the test strip. The convex portion 114 of the lower housing 100 specifically prevents the sample leaked from the area “a” where the sample may accumulate in the direction in which the sample is developed, and the convex portion 115 prevents the d...

Embodiment 2

[0130] Figure 8 The configuration of a modified embodiment of the device according to the invention is shown, wherein additional protrusions 701 and 702 are arranged for confining the test strip 150 in the height direction of the device.

[0131] The additional protrusion 701 has a function of guiding the excess sample to the area “a” by contacting the lower surface of the test strip 150 . The additional protrusion 702 is a protrusion protruding toward the test strip 150 from the inner surface of the upper case, and it pushes the end of the test strip 150 on the opposite side in the deployment direction to the lower case. Thereby, excess sample is directed to zone "a". Reference numeral 703 denotes a bottom on the sample pad side in the longitudinal direction of the opening of the detection window, which slightly touches the test strip to prevent the test strip from floating, thereby producing a rectification of the sample in the width direction. Reference numeral 704 denot...

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Abstract

Provided is a test device for immunochromatography that is capable of accurate assessment even in cases in which an excess of test liquid has been introduced therein. Specifically provided is a test device for immunochromatography comprising a test piece, a lower housing having a plurality of support bases for supporting the test piece, and an upper housing having a drop opening for dropping a sample upon the test piece and having a detection window in the direction in which the sample introduced from the drop opening spreads upon the test piece, wherein the width of the support base supporting the portion of the test piece exposed by the detection window is narrower than the width of the test piece, or the width of the support base, from among the plurality of support bases, that is disposed between a position in the lower housing corresponding to the detection window and a position in the lower housing corresponding to the drop opening is wider than the width of the test piece.

Description

technical field [0001] The present invention belongs to the technical field of immunochromatographic tests using antigen-antibody reactions. More specifically, the present invention relates to devices for immunochromatographic tests. Background technique [0002] Immunochromatography is known to be a clinical diagnostic method capable of simple and rapid diagnosis based on the specificity of antigen-antibody immune reactions using biological samples such as urine, feces, saliva, blood, serum, and pharyngeal fluid. Immunochromatography is performed by using a strip such as nitrocellulose in which a pad impregnated with a primary antibody color-marked with a colloidal gold carrier is arranged at one end and a capture site (test line) is arranged at the other end, and the A liquid biological sample is dropped into the pad, whereby a mixture of the sample, the primary antibody and the complex formed by the antigen-antibody reaction between the antigen in the sample and the prim...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/543
CPCG01N33/54388B01L3/5023B01L2200/026B01L2200/141B01L2200/16B01L2300/025B01L2300/069B01L2300/08B01L2300/0825G01N33/54386
Inventor 东加奈子奥山慎也齐藤和典河野景吾森田元喜
Owner SEKISUI MEDICAL CO LTD
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