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New purpose of Huahong composition preparation to preparation of medicines for resisting breast cancer

An anti-breast cancer, composition technology, applied in the direction of anti-tumor drugs, drug combinations, antipyretic drugs, etc., to achieve the effect of inhibiting the growth of transplanted tumors in mice, with a wide range of sources and ideal use effects

Inactive Publication Date: 2020-09-22
广西壮族自治区花红药业集团股份公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] At present, there are no literatures at home and abroad to report that the preparation of the bonus composition is used for the treatment of breast cancer.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] 1. Composition of raw materials: 1250g of red dianthus, 750g of Hedyotis diffusa, 1250g of Peach Blossom, 750g of white back leaf root, 750g of scorpion, 1000g of Caulis Spatholobus, 1250g of myrtle root, 10g of hydroxypropyl methylcellulose, talc powder 20g, magnesium stearate 10g, silicon dioxide 130g.

[0022] 2. Preparation method: a little red, Hedyotis diffusa, Peach Blossom, white back leaf root, scorpion, myrtle root, Caulis Spatholobus, the above seven flavors, take 300g of a little red, crush it into fine powder, and the remaining a little red and For the remaining six flavors such as Hedyotis diffusa, add water and decoct twice, the first time for 2 hours, the second time for 1.5 hours, combine the decoction liquid, filter, and concentrate the filtrate to a clear paste with a relative density of 1.18-1.23 (80°C) , add ethanol until the alcohol content reaches 65%, stir evenly, let it stand for 24 hours, filter, recover ethanol from the filtrate under reduced ...

Embodiment 2

[0024] 1. Composition of raw materials: 1667g of a little red, 1000g of Hedyotis diffusa, 1667g of Peach Blossom, 1000g of white back leaf root, 1000g of 菥蓂, 1333g of Caulis Spatholobus, 1667g of myrtle root, 120g of starch, 20g of microcrystalline cellulose, hard Magnesium fatty acid 20g.

[0025] 2. Preparation method: add water to extract two medicinal materials including a little red, Hedyotis diffusa, Peach Blossom, white back leaf root, 菥蓂, myrtle root, and Caulis Spatholobus, the first time is 2 hours, and the second time is 1.5 hours, combine the decoction liquid, filter, concentrate the filtrate to a clear paste with a relative density of 1.18-1.23 (80°C), add ethanol until the alcohol content reaches 65%, stir well, let stand for 24 hours, filter, and decompress the filtrate The ethanol is recovered and concentrated to a thick paste with a relative density of 1.20-1.25 (60°C), spray-dried and granulated, packed into capsules, and made into 1000 granules.

Embodiment 3

[0027] 1. Composition of raw materials: 5000g of red dianthus, 3000g of Hedyotis diffusa, 5000g of Peach Blossom, 3000g of white back leaf root, 3000g of scorpion, 4000g of Mildew Spatholobus, 5000g of myrtle root, 3580g of starch, 20g of stevia.

[0028] 2. Preparation method: a total of seven medicinal materials including a little red, hedyotis diffusa, ground peach blossom, white back leaf root, scorpion, myrtle root, and spathula, add water and boil twice, the first time for 2 hours, and the second time After 1.5 hours, combine the decoction, filter, concentrate the filtrate to a relative density of 1.20 (80°C), add ethanol until the alcohol content reaches 65%, stir well, let stand for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure. Concentrate to a thick paste with a relative density of 1.25-1.30 (80°C), add appropriate amount of starch and stevia, mix well, make granules, dry, and pack into 1000 bags.

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Abstract

The invention relates to the technical field of traditional Chinese medicines, and provides a new purpose of a Huahong composition preparation to preparation of medicines for resisting breast cancer.The Huahong composition is prepared from the following medicines in parts by weight of 1000-5000 parts of dried emilia sonchifolia herbs, 500-6600 parts of dried hedyotis diffusa herbs, 1000-5000 parts of dried urena lobata aboveground parts, 500-6600 parts of dried mallotus apelta roots and rhizomes, 500-6600 parts of dried thlaspi arvense aboveground parts, 1000-7500 parts of dried spatholobus suberectus rhizomes and 1000-5000 parts of dried rhodomyrtus tomentosa roots. The Chinese patent medicine namely the Huahong composition preparation has favorable restraining effects on breast cancer cells, a theoretical basis is provided for the new purpose of old medicines, and a new thought is provided for developing anti-cancer effects of the Huahong composition.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to the new application of a flower red composition preparation in the preparation of anti-breast cancer drugs. Background technique [0002] Huahong composition preparation is a kind of Chinese patent medicine, the main ingredients include a little red, Hedyotis diffusa, Peach Blossom, white back leaf root, scorpion, Mildew Spatholobus and myrtle root. The effect of dispelling blood stasis and relieving pain is used for leukorrhagia and irregular menstruation caused by damp heat and stagnation. Symptoms include profuse leukorrhea, thick yellow color, dull pain in the lower abdomen, lumbosacral pain, and abdominal pain during menstruation; chronic pelvic inflammatory disease, adnexitis , Endometritis see the above syndrome. [0003] A little red, the dry whole herb of Emilia sonchifolia (L.) DC. (Source: "Guangxi Zhuang Autonomous Region Zhuang Medicine Quality ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61P35/00A61P35/04A61P29/00A61P25/00
CPCA61K36/28A61K36/748A61K36/185A61K36/47A61K36/31A61K36/486A61K36/61A61P35/00A61P35/04A61P29/00A61P25/00A61K2300/00
Inventor 韦飞燕张艳华刘春明韦金燕唐满姣张伟
Owner 广西壮族自治区花红药业集团股份公司
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