Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine composition, preparation, method and application for preventing and treating hyperuricemia

A technology of hyperuricemia and composition, which is applied in the field of traditional Chinese medicine composition for the prevention and treatment of hyperuricemia, can solve the problems of large side effects, etc., and achieve the goal of reducing complications of hyperuricemia, significantly reducing uric acid, and reducing serum uric acid Effect

Active Publication Date: 2022-04-19
TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently, allopurinol, febuxostat, benzbromarone, etc. are available for the treatment of hyperuricemia. However, long-term use of these drugs has serious side effects, and traditional Chinese medicine has its own advantages in terms of treatment methods and drug applications. It has unique advantages, and it is a popular trend in recent years to treat diseases with a variety of traditional Chinese medicine combinations. It can be treated from multiple components, multiple targets, and multiple channels. At present, there are few products on the market that prevent and treat hyperuricemia. Therefore, It has practical significance and application value to search for new safe and effective urate-lowering functional drugs

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition, preparation, method and application for preventing and treating hyperuricemia
  • Traditional Chinese medicine composition, preparation, method and application for preventing and treating hyperuricemia
  • Traditional Chinese medicine composition, preparation, method and application for preventing and treating hyperuricemia

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0039] The preparation method of the traditional Chinese medicine composition for preventing and treating hyperuricemia as described above, the steps are as follows:

[0040] A. Add the four medicinal materials of kudzu flower, red peony root, white peony root and Hovenia dulcis fruit respectively to 60-95% ethanol which is 10-30 times its weight, heat and reflux to extract 1-3 times, each time for 2-5 hours, and depressurize Concentrate and dry to obtain kudzu flower extract, red peony extract, white peony extract and Hovenia dulcis extract;

[0041] B, after dissolving the kudzu flower extract, the red peony extract and the white peony extract described in step A respectively with distilled water, extract with sherwood oil 3 times respectively to obtain kudzu flower petroleum ether layer and water layer, red peony petroleum ether layer And the water layer and the white peony petroleum ether layer and the water layer;

[0042] C, extract the kudzu flower water layer, the red...

Embodiment 1

[0047] The preparation of embodiment 1 granule of the present invention

[0048] Formula: 10.8 parts of ethyl acetate layer of kudzu flower, 8.1 parts of ethyl acetate layer of red peony, 64.9 parts of ethyl acetate layer of white peony, 16.2 parts of Hovenia dulcis fruit extract.

[0049] Preparation method: Add the four medicinal materials of kudzu flower, red peony root, white peony root and Hovenia dulcis fruit respectively to 60-95% ethanol which is 10-30 times its weight, heat and reflux to extract 1-3 times, each time for 2-5 hours, reduce Concentrate and dry under pressure to obtain kudzu flower extract, red peony extract, white peony extract and Hovenia dulcis seed extract; after dissolving the extracts with distilled water, extract with petroleum ether for 3 times respectively to obtain the water layer from which the petroleum ether layer has been removed; Extract the water layer with ethyl acetate for 3 times respectively to obtain the ethyl acetate layer of kudzu f...

Embodiment 2

[0050] The preparation of embodiment 2 capsules of the present invention

[0051] Formula: 10.8 parts of ethyl acetate layer of kudzu flower, 8.1 parts of ethyl acetate layer of red peony, 64.9 parts of ethyl acetate layer of white peony, 16.2 parts of Hovenia dulcis fruit extract.

[0052] Preparation method: The method is the same as in Example 1 to obtain the ethyl acetate layer of kudzu flower, ethyl acetate layer of red peony root, ethyl acetate layer of white peony root and Hovenia dulcis fruit extract dry powder, add microcrystalline cellulose and disintegrant to granulate, and The granules are packed into capsules.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5 to 30 parts of flos puerariae ethyl acetate layer, 1 to 30 parts of radix paeoniae rubra ethyl acetate layer, 10 to 100 parts of radix paeoniae alba ethyl acetate layer and 10 to 80 parts of semen hoveniae extract. The composition integrates active ingredients of four traditional Chinese medicines, has an extremely remarkable uric acid reducing effect and has an effect of possibly reducing hyperuricemia complications, the hovenia dulcis thunb in the formula belongs to homology of medicine and food, and the radix paeoniae alba and the radix paeoniae rubra are traditional Chinese medicines capable of being used as health-care foods, so that the safety of the composition is improved, and the composition has a very good practical application value.

Description

technical field [0001] The invention belongs to the technical field of medicines, in particular to a traditional Chinese medicine composition, preparation, method and application for preventing and treating hyperuricemia. Background technique [0002] In recent years, the incidence of hyperuricemia and gout in my country has shown a significant increase and younger trend. According to conservative estimates, the number of patients with hyperuricemia in my country has reached 177 million, accounting for about 13.3% of the total population. Hyperuricemia has become the "fourth highest" clinically after hypertension, hyperlipidemia, and hyperglycemia. [0003] Hyperuricemia refers to the disorder of purine metabolism in the body, excessive production or less secretion of uric acid, so that uric acid accumulates in the blood, causing blood uric acid to rise, exceeding the normal concentration of plasma. Hyperuricemia not only causes gout, but also plays a role in hypertension, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/72A61P19/06
CPCA61K36/488A61K36/71A61K36/65A61K36/72A61P19/06A61K2236/35A61K2236/333A61K2236/39A61K2236/51A61K2300/00Y02A50/30
Inventor 刘振白鑫明周远卓张风高俊玲李昕冉向岑滕玉鸥郁彭
Owner TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com