Oil control composition and application thereof
An oil composition and oil product technology, which can be applied to cosmetic preparations, medical preparations containing active ingredients, cosmetics, etc., can solve the problems of unable to maintain the skin continuously and repair the skin barrier, and reduce the problem of system instability. , Superior oil secretion, avoid discoloration effect
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Embodiment 1
[0024] Example 1 Preparation of Oil Control Composition
[0025] According to the composition of samples 1-6 and comparative samples 1-5 in the following table 1 (g), weigh ectoine, spiraea elm extract, and 10-hydroxydecanoic acid respectively, add distilled water until completely dispersed and dissolved, and fully Stir and mix evenly, and freeze-dry to obtain an oil control composition; comparison samples 6-8 are used directly.
[0026] Table 1 Formulas of different oil control compositions
[0027] .
Embodiment 2
[0028] Example 2 The inhibitory effect of different products on the secretion of sebaceous glands
[0029] In the process of cell culture, the oil control effect of the experimental examples and comparative examples was investigated by investigating the synthesis of neutral lipids in human sebocytes:
[0030] SZ95 human sebocytes cultured in vitro were selected, and the cells were cultured in Sebomed basal medium, supplemented with 10% fetal bovine serum, 5 μg / L epidermal growth factor, 100 U / ml penicillin, and 100 μg / ml streptomycin. Placed at 37°C, 5% CO 2 In the incubator, the culture medium was changed every 2 days. Cells were seeded in a 96-well plate, and samples 1-6 and control samples 1-8 of the same quality were added the next day. After incubation for 48 hours, the supernatant was discarded, washed twice with PBS, and divided into two parts after repeated pipetting, and one part was diluted with PBS. Nile Red dye (1 mg / ml, dissolved in acetone, stored at -20°C) to ...
Embodiment 3
[0035] Example 3 Preparation of Oil Control Emulsion
[0036] Prepare the oil control emulsion according to the raw materials in the table below, and use the conventional method to prepare the oil control emulsion. The numbers prepared by samples 1-6 are Application Examples 1-6, and the numbers prepared by Comparative Samples 1-8 are Application Examples 8-15.
[0037] table 3
[0038]
[0039]The preparation method of the oil control emulsion is: add purified water into the emulsification tank, then add xanthan gum, betaine, glycerin, methylparaben and propylparaben into the emulsification tank in sequence, stir and heat to 75-80°C, Cetearyl alcohol glucoside, cetearyl alcohol, dioctyl carbonate, isononyl isononanoate, and VE acetate are sequentially added to the oil phase tank, heated to 75-80°C, and then pumped into the emulsification tank. After a few minutes, when the temperature is lowered to 40-45°C, add the oil control composition prepared in Example 1 and phenoxy...
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