Essence capable of improving acne marks and scars and preparation method thereof
A scar and acne scar technology, applied in skin care preparations, medical preparations containing active ingredients, pharmaceutical formulations, etc., to achieve the effect of repairing acne marks and scars, repairing acne marks and scars, and inhibiting excessive proliferation
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Embodiment 1
[0031] Embodiment 1, preparation of slender geranium alcohol extract
[0032] Take slender geranium hay, wash, dry, and pulverize into fine powder; add 55% ethanol solution according to the ratio of 1g:15ml of solid to liquid, reflux extraction twice, combine the extracts, remove ethanol under reduced pressure, and concentrate to obtain .
Embodiment 2
[0033] Example 2. Preparation of a composition that can improve acne marks and scars
[0034] S1. According to the added volume of the slender geranium extract being 22% of the volume of the yeast medium, mix the slender geranium extract with the yeast medium, and sterilize at 121° C. to obtain a primary fermentation substrate;
[0035] S2. Inoculate the above-mentioned primary fermentation substrate with Candida CGMCC2.1763 cultured on a shaking table in advance, so that the yeast concentration in the substrate is 8×10 6 cfu / ml, for fermentation, after the fermentation, take the fermentation liquid, sterilize, and let it stand for cooling to obtain the primary fermentation active substance. The fermentation parameters are: pH value is 4.3-5.8; stirring speed is 100-200rpm; 4VVM; fermentation temperature is 28°C; fermentation time is 4 days;
[0036] S3. According to the added volume of the primary fermentation active substance being 15% of the volume of the C. nigriscens cul...
Embodiment 3
[0038] Example 3. Preparation of a composition that can improve acne marks and scars
[0039] S1. According to the added volume of the slender geranium extract being 16% of the volume of the yeast medium, mix the slender geranium extract with the yeast medium, and sterilize at 121° C. to obtain a primary fermentation substrate;
[0040] S2. Inoculate the above-mentioned primary fermentation substrate with Candida CGMCC2.1763 cultured on a shaking table in advance, so that the yeast concentration in the substrate is 8×10 6 cfu / ml, for fermentation, after the fermentation, take the fermentation liquid, sterilize, and let it stand for cooling to obtain the primary fermentation active substance. The fermentation parameters are: pH value is 4.3-5.8; stirring speed is 100-200rpm; 4VVM; fermentation temperature is 30°C; fermentation time is 3 days;
[0041] S3. According to the added volume of the primary fermentation active substance being 18% of the volume of the C. nigriscens cul...
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