8 results about "Xylaria sp." patented technology

The invention provides cytochalasin based on soil fungi Xylaria sp. Y01 and application of the cytochalasin, and belongs to the technical field of medicinal chemistry. According to the invention, 27 kinds of cytochalains are separated from a soil fungus Xylaria sp. Y01, wherein the 27 kinds of cytochalains comprise 13 kinds of newly discovered compounds. It is explored whether these compounds have an inhibitory effect on the release of pro-inflammatory cytokines. The result shows that the compound 22 shows a remarkable anti-inflammatory effect on RAW264.7 cells by up-regulating the expression of SOCS3. Therefore, the compound 22 is expected to become a potential candidate drug for developing drugs for treating inflammatory diseases.

This invention belongs to the field of microbial technology, specifically disclosing a method for artificially cultivating *Anthraquinone longipes* containing camptothecin using bamboo shoot shell waste. The method involves inoculating *Anthraquinone longipes* into SKG medium for cultivation. The SKG medium consists of bamboo shoot shell powder with a solid-liquid ratio of 20:20 and MS medium with a concentration of 0.5 g / L. This invention is the first to achieve the artificial cultivation of *Anthraquinone longipes* fruiting bodies using waste bamboo shoot shells. Furthermore, the secondary metabolites of the cultivated fruiting bodies were evaluated, revealing that the fruiting bodies can produce camptothecin, thus enhancing the economic value of *Anthraquinone longipes* and providing a new pathway for the industrial production of camptothecin.

The invention relates to the technical field of microorganisms, and particularly provides xylaria T-1 capable of efficiently degrading carotenoid, a screening method and application of the xylaria T-1 in Baijiu brewing. The xylaria T-1 disclosed by the invention is separated and screened from wine brewing fermented grains and is preserved in the China Center for Type Culture Collection (CCTCC), and the preservation number is CCTCC NO: M 20251662. The strain can effectively degrade carotenoid to generate various terpenoid derivatives with special fragrance or functions such as beta-ionone and dihydroactinidiolide, the content and types of terpenoid substances in fermented grains can be remarkably increased by adding the strain into the fermented grains, and the quality of white spirit is improved.

The invention belongs to the technical field of microorganisms, and particularly discloses a method for artificially cultivating xylaria nigripes containing camptothecin by utilizing bamboo shoot shell waste, the specific method is that xylaria nigripes strains are inoculated to an SKG culture medium for cultivation, and the SKG culture medium is composed of bamboo shoot shell powder and an MS culture medium with the concentration of 0.5 g / L according to the solid-to-liquid ratio of 20: 20. According to the method, the waste bamboo shoot shells are used for achieving artificial cultivation of the xylaria nigripes sporocarp for the first time, secondary metabolite evaluation is conducted on the cultivated sporocarp, it is found that the sporocarp can produce camptothecin, the economic value of the xylaria nigripes is improved, and meanwhile a new way is provided for industrial production of camptothecin.

The invention discloses a longitudinal stripe xylaria and poria cocos prebiotic functional beverage and a preparation method thereof, and belongs to the technical field of functional beverages. Comprising the following raw materials in parts by weight: 220 to 280 parts of a xylaria striata extracting solution, 90 to 130 parts of a poria cocos extracting solution, 0.6 to 1.0 part of vitamin C, 0.012 to 0.028 part of vitamin B6, 0.00012 to 0.00026 part of vitamin B12, 0.06 to 0.1 part of zinc gluconate, 8 to 15 parts of erythritol, 3 to 6 parts of arabinose, 5 to 10 parts of trehalose, 40 to 60 parts of concentrated apple juice, 20 to 35 parts of concentrated dark plum juice, 15 to 30 parts of concentrated mulberry juice, 0.9 to 1.3 parts of citrus fiber and the balance of pure water. The total amount is 1000 parts. A longitudinal stripe xylaria extracting solution and a poria cocos extracting solution are compounded, the synergistic interaction effects of the longitudinal stripe xylaria extracting solution and the poria cocos extracting solution in the aspects of oxidation resistance and sleep aiding are fully exerted, and the flavor and taste of the product are effectively improved on the premise that artificial essence, a synthetic sweetening agent and a preservative are not needed to be added by selecting a prebiotic sweetening agent and a composite natural fruit juice system.

The invention discloses an efficient cultivation method for longitudinal stripe xylaria, and belongs to the technical field of fungus planting, the method comprises the following steps: S1, preparing a solid culture material which comprises the following components in percentage by mass: 40-46% of sawdust, 15-25% of bran, 25-35% of corncob, 1-3% of gypsum powder and 1-3% of lime powder, S2, crushing the sawdust and the corncob, mixing the crushed sawdust and corncob with the bran, the gypsum powder and the lime powder, and uniformly stirring to obtain a mixture; the method comprises the following steps: S1, inoculating a mother strain mycelium of longitudinal stripe xylaria into a sterilized solid culture material in a planting bottle under a sterile condition, S4, placing the inoculated planting bottle in a culture room, S5, continuing to culture after the mycelium overgrows the planting bottle, and S6, obtaining a longitudinal stripe xylaria sporocarp. The yield of the sporocarp is remarkably improved and is far higher than that of a traditional formula, the quality of the sporocarp is stable, the formula is designed according to the nutritional requirements of the longitudinal stripe xylaria, the nutrient absorption efficiency is improved, key environmental parameters such as temperature and humidity are defined, fruiting management is optimized in combination with seasonal characteristics, and the influence of environmental fluctuation on the yield is reduced.

The invention relates to the field of biological disease and pest control, provides an oligopeptide and disaccharide composition capable of realizing an efficient and lasting nematode killing effect by regulating pine wood nematode associated flora, and is suitable for green prevention and control of pine wood nematode diseases. Aiming at the problems of high toxicity, large dosage and damage to microecological balance of the existing prevention and treatment means, the invention develops a preparation consisting of oligopeptide PS3 (amino acid sequence DLYVMF, which can be extracted or artificially synthesized through fermentation of xylaria strain sj18) and disaccharide (trehalose or maltose). The action mechanism is specific regulation and control of nematode associated flora, and no direct nematode killing effect exists. When the concentration of PS3 is 340 ppm and the concentration of disaccharide is 1250 ppm, the fatality rate of pine wood nematodes in 24 hours is 47.7%, and the fatality rate of pine wood nematodes in 48 hours reaches 96%. The composition is safe and efficient, and solves the technical problems of existing medicaments.

This invention relates to the field of microbial technology and its application. Xylaria curta (QPZ-01) is deposited at the Guangdong Provincial Microbial Culture Collection Center (GDMCC NO: 64782) on July 10, 2024. The invention also discloses its application in the fermentation of fibrinolytic enzymes. This invention provides an Xylaria curta strain and its application.