A device for assessing collateral vessel and tissue function based on cerebral blood flow

A technology for evaluating the cerebral blood flow, which is applied in the directions of blood flow measurement, catheter, cardiac catheter, etc., can solve the problems of difficult visualization of tertiary collateral circulation, difficult to realize ischemic penumbra evaluation, etc.

Active Publication Date: 2022-05-27
THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL +1
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Problems solved by technology

Cerebral collateral circulation is divided into three levels, among which the third-level collateral circulation is related to the ischemic penumbra, which often refers to the rapid establishment of small arteries after the occurrence of ischemic stroke to supply blood to the ischemic penumbra. This kind of tertiary collateral circulation imaging can well reflect the existence and extent of the ischemic penumbra; although the existing imaging technology can image the first and second-order collateral circulation, it is difficult to visualize the tertiary collateral circulation. It is still a difficult point, which makes it difficult to evaluate the ischemic penumbra based on the visualization of collateral circulation

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  • A device for assessing collateral vessel and tissue function based on cerebral blood flow
  • A device for assessing collateral vessel and tissue function based on cerebral blood flow
  • A device for assessing collateral vessel and tissue function based on cerebral blood flow

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Embodiment Construction

[0025] In order to facilitate the understanding and implementation of the present invention by those of ordinary skill in the art, the present invention will be further described in detail below with reference to the embodiments. It should be understood that the embodiments described herein are only used to illustrate and explain the present invention, but not to limit the present invention.

[0026] A method for evaluating collateral vessels and tissue function based on cerebral blood flow, comprising the following steps:

[0027] Step 1, registration of cerebral blood flow maps of multiple delay times of patients diagnosed with aortic occlusive infarction, so that the cerebral blood flow maps of each delay time are mapped one by one on the spatial anatomical structure.

[0028] In the clinical magnetic resonance examination of large artery occlusive infarction, the imaging sequence scanning sequence is generally the first structural imaging to obtain the structural image (T1 / ...

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Abstract

The invention discloses a collateral vessel and tissue function evaluation method based on cerebral blood flow. Firstly, multiple delay time cerebral blood flow maps of patients diagnosed with aortic occlusive infarction are registered to realize their spatial anatomical structure one by one. Correspondence; secondly, remove the braincase and extracerebral structures of the brain blood flow map at multiple delay times after registration, and calculate the difference map of cerebral blood flow at multiple delay times; then, visualize the cerebral collateral blood flow circulation, and quantify the lateral Information related to branch blood flow, such as the distribution range of collateral blood flow, flow velocity, flow rate, etc.; finally, combined with the infarct core area of ​​patients diagnosed with large artery occlusive infarction, evaluate the ischemic penumbra, such as the size of the ischemic penumbra, size, location, etc.

Description

technical field [0001] The invention belongs to the technical field of magnetic resonance imaging and medical image processing, and in particular relates to a method for evaluating the function of collateral vessels and tissues based on cerebral blood flow. Background technique [0002] The currently widely used method is to use the perfusion imaging method of injecting contrast agent to obtain a pixel-level contrast agent inflow-time curve, so as to obtain multiple parameters that can reflect hemodynamics, such as average transit time, peak time, The peak reflection time, etc., is determined by defining the time threshold to determine the severe hypoperfusion area, thereby forming a mismatch with the brain tissue death area to reflect the ischemic penumbra. However, the limitations of this method are obvious. First, it may not be the ischemic penumbra that reflects severe hypoperfusion simply by setting the time threshold. It also includes benign hypoperfusion areas. Second...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/02A61B5/026
CPCA61B5/0263A61B5/02007A61B5/72
Inventor 娄昕周欣吕晋浩邓鹤肖洒孙献平叶朝辉
Owner THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL
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