A device for assessing collateral vessel and tissue function based on cerebral blood flow

Abstract

The invention discloses a collateral vessel and tissue function evaluation method based on cerebral blood flow. Firstly, multiple delay time cerebral blood flow maps of patients diagnosed with aortic occlusive infarction are registered to realize their spatial anatomical structure one by one. Correspondence; secondly, remove the braincase and extracerebral structures of the brain blood flow map at multiple delay times after registration, and calculate the difference map of cerebral blood flow at multiple delay times; then, visualize the cerebral collateral blood flow circulation, and quantify the lateral Information related to branch blood flow, such as the distribution range of collateral blood flow, flow velocity, flow rate, etc.; finally, combined with the infarct core area of ​​patients diagnosed with large artery occlusive infarction, evaluate the ischemic penumbra, such as the size of the ischemic penumbra, size, location, etc.

Description

technical field [0001] The invention belongs to the technical field of magnetic resonance imaging and medical image processing, and in particular relates to a method for evaluating the function of collateral vessels and tissues based on cerebral blood flow. Background technique [0002] The currently widely used method is to use the perfusion imaging method of injecting contrast agent to obtain a pixel-level contrast agent inflow-time curve, so as to obtain multiple parameters that can reflect hemodynamics, such as average transit time, peak time, The peak reflection time, etc., is determined by defining the time threshold to determine the severe hypoperfusion area, thereby forming a mismatch with the brain tissue death area to reflect the ischemic penumbra. However, the limitations of this method are obvious. First, it may not be the ischemic penumbra that reflects severe hypoperfusion simply by setting the time threshold. It also includes benign hypoperfusion areas. Second...

AI Technical Summary

Problems solved by technology

Cerebral collateral circulation is divided into three levels, among which the third-level collateral circulation is related to the ischemic penumbra, which often refers to the rapid establishment of small arteries after the occurrence of ischemic stroke to supply blood to the ischemic penumbra. This kind of tertiary collateral circulation imaging can well reflect the existence and extent of the ischemic penumbra; although the existing imaging technology can image the first and second-order collateral circulation, it is difficult to visualize the tertiary collateral circulation. It is still a difficult point, which makes it difficult to evaluate the ischemic penumbra based on the visualization of collateral circulation

Images