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A single light source multi-sample fluorescence detection optical system and its working method

A fluorescence detection and optical system technology is applied in the field of fluorescence detection optical systems to achieve the effects of improving the signal-to-noise ratio, saving detection costs, and improving detection effects.

Active Publication Date: 2022-02-18
SUZHOU MOLARRAY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the difficulty lies in: the design of the plastic light guide rod, that is, the size of the plastic light guide rod needs to meet certain conditions in order to have a better working state

Method used

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  • A single light source multi-sample fluorescence detection optical system and its working method
  • A single light source multi-sample fluorescence detection optical system and its working method
  • A single light source multi-sample fluorescence detection optical system and its working method

Examples

Experimental program
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Effect test

Embodiment 1

[0072] Embodiment one, such as figure 1 As shown, a fluorescence detection optical system with a single light source and multiple samples includes: a light source emitting component 100, a light source receiving component 200, and a light guide-reaction component 300;

[0073] Wherein, the light source emitting assembly 100 includes: LED lamp 101 (using LED as the light source, the service life can reach 20,000 hours, of course, it is also feasible to use other monochromatic light sources, such as: halogen tungsten lamp), the first convex lens 102 (spherical mirror), the second Two convex lenses 103 (spherical mirror), excitation filter 104, light guide strip assembly 105; the LED lamp faces downward, the convex surface of the first convex lens 102 faces downward, and the second convex lens 103 is arranged on the first Below the convex lens 102 and the convex surface of the second convex lens 103 faces downward;

[0074] The upper surface of the second convex lens is circular...

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Abstract

The invention discloses a fluorescence detection optical system with a single light source and multiple samples and its working method, which belongs to the field of molecular diagnostic detection instruments. The light source emitting assembly includes: a light source, a lens assembly, an excitation filter, and a light guide bar assembly; the light guide bar assembly includes N vertically arranged light guide bars; wherein, the light guide-reaction assembly includes: a light guide plate, a reaction Pool assembly; Wherein, light source receiving assembly comprises: CCD camera, camera lens, receiving optical filter; The lower end of CCD camera is provided with camera lens, is provided with receiving optical filter at the lower end of camera lens; Described CCD camera is arranged on Above the light guide plate with the lens facing the light guide plate. The present invention aims to provide a fluorescence detection optical system with single light source and multiple samples and its working method, which can detect 128 samples at one time.

Description

technical field [0001] The present invention relates to the fields of a medical inspection instrument and a molecular diagnosis instrument, and more specifically relates to a fluorescence detection optical system with a single light source and multiple samples and a working method thereof. Background technique [0002] Multi-sample fluorescence detection optical system is a development direction of molecular diagnostic detection equipment. [0003] Regarding the multi-sample fluorescence detection optical system, the existing technologies are as follows: [0004] Shanghai Lanyi Technology Co., Ltd. discloses a multi-sample microbial detection device in CN104964927A, which simultaneously completes the multi-parameter detection of colorimetry, turbidimetry and fluorescence of a matrix sample hole by scanning, and can simultaneously detect 16 samples to be tested . The detection method of the detection device of the invention is simple and efficient, and has good application ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/64G01J3/44G01J3/28G01J3/10
CPCG01N21/645G01N21/64G01J3/10G01J3/4406G01J3/2823G01N2021/6482G01N2021/6463G01N2021/6417
Inventor 李晓刚王威梅宗羲李慧王野聂晶
Owner SUZHOU MOLARRAY CO LTD
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