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Osmotic actuator for injecting device and injection device comprising osmotic actuator

A technology of injection device and actuator, applied in the directions of syringes, transportation and packaging, ampoule syringes, etc., which can solve the problems of decreasing flow rate and reducing osmotic potential, etc.

Active Publication Date: 2021-04-02
萨博库杰克特有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004]However, when water enters the osmotic actuator through the osmotic membrane, the draw solution inside the osmotic actuator is diluted, and the water near the osmotic membrane in the pressure chamber The boundary layer reduces the osmotic potential and causes the flow velocity to decrease with time

Method used

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  • Osmotic actuator for injecting device and injection device comprising osmotic actuator
  • Osmotic actuator for injecting device and injection device comprising osmotic actuator
  • Osmotic actuator for injecting device and injection device comprising osmotic actuator

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Embodiment Construction

[0081] In the following description only that which is necessary to understand the function of the different embodiments of the osmotic actuator 110 is included. The described ways of mixing and circulating flow or moving ions / particles to the permeable membrane 130 can be combined digitally and are within the scope of the present invention. The terms "mixing" and "circulation" are used interchangeably in the specification as means for creating a more uniform draw solution within the pressure chambers 180 , 280 , 380 of the osmotic actuator 110 .

[0082] The terms "upper", "lower", "upper", "lower" and "downward" refer to the drawings and not necessarily to the usage.

[0083] The term "wearable injection device" 100 refers to a patient administration injection device 100 for attaching to a user's body and for subcutaneously injecting a drug into the user's tissue. Typical amounts of medicament to be injected range from 1 ml to 20 ml. The wearable injection device 100 injec...

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PUM

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Abstract

An osmotic actuator (110) for an injection device (100) is disclosed, and the osmotic actuator (110) comprises a pressure chamber (180; 280; 380) having one or more outlets (182; 282; 295; 395) and containing a draw solution, one or more osmotic membranes (130), a cavity (140) containing water, and a dilution-compensating arrangement, wherein the one or more osmotic membranes (130) forms a part ofan internal surface area of the pressure chamber (180; 280; 380), the cavity (140) containing water abuts at least part of an external surface of the one or more osmotic membranes (130), and the dilution-compensating arrangement is arranged to compensate for the dilution of the draw solution near the one or more osmotic membranes (130), which occurs when water from the cavity (140) enters the pressure chamber (180; 280; 380) through the one or more osmotic membranes (130). Furthermore, the injection device (100) comprising the osmotic actuator (110) is disclosed.

Description

technical field [0001] The present invention relates to an osmotic actuator for an injection device and capable of providing a steady flow rate during use of the device. Background technique [0002] Using an osmotic actuator as the drive unit of an injection device is very attractive in situations where the drug has to be injected slowly into the patient, for example when a large volume of drug has to be injected. Osmotic actuators are capable of providing very high pressures, but the pressure build-up time can be easily controlled by the type and size of the osmotic membrane and the concentration and type of osmotic draw solution. The pressure and increased volume in the actuator due to feed water passing through the permeable membrane and entering the actuator can be used to move the plunger or squeeze the flexible reservoir in the barrel. [0003] WO2017 / 129191 describes a number of embodiments of wearable injection devices equipped with a drive unit in the form of an o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/142A61M5/145A61K9/00A61M5/24
CPCA61M5/14248A61M5/145A61M5/2466A61M2005/14252A61M2005/14513A61K9/0004A61M2205/273A61M2205/82A61J1/065
Inventor 克劳斯·施密特·莫勒图厄·谢尔高·托夫特托马斯·施滕贝格托马斯·贡德贝格
Owner 萨博库杰克特有限公司