Injection systems for drug delivery with internal force transmission

A drug and internal space technology, applied in the field of injection systems, can solve problems affecting patient/user experience

Active Publication Date: 2021-05-14
AMGEN INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This places constraints on the shape and / or material used for the housing which in turn affects the patient / user experience

Method used

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  • Injection systems for drug delivery with internal force transmission
  • Injection systems for drug delivery with internal force transmission
  • Injection systems for drug delivery with internal force transmission

Examples

Experimental program
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Embodiment Construction

[0020] The present disclosure generally relates to the configuration and operation of injection systems for drug delivery. Although most embodiments are described in the context of hand-held injectors such as auto-injectors, the scope of the present disclosure is not limited to such injectors. Other injection systems to which the present disclosure may be applied include, but are not limited to: wearable injectors such as on-body injectors that adhere to the patient's skin (e.g., via an adhesive), portable pumps that are worn on the patient's clothing, Hybrid Auto-Injector / Pocket Syringe.

[0021] In general, injection systems of the present disclosure are designed to limit the number of parts or components that are subject to mechanical stress or load due to the force output by the energy source. The set or sets of components placed under mechanical stress or load may vary depending on whether the injection system is in a pre-injection state, an injection state or a post-inj...

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PUM

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Abstract

Injection systems for drug delivery are disclosed. A system may include a container filled or tillable with a drug, a stopper movably disposed in the container, a plunger, an energy source outputting a force, a mechanical linkage operable to transmit the force output by the energy source to the plunger to cause the plunger to act on the stopper to expel the drug from the container, and a trigger member. The system may have pre-injection state where the trigger member inhibits actuation of the mechanical linkage, an injection state where the trigger member permits actuation of the mechanical linkage, and a post-injection state where the plunger is stationarily positioned in an end-of-dose position. The system may be designed to limit the number of components included in various force transmission loops present in the pre-injection, injection, and / or post-injection states.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. Provisional Patent Application No. 62 / 740,232, filed October 2, 2018, which is incorporated herein by reference in its entirety. technical field [0003] The present disclosure relates generally to injection systems for drug delivery, and more particularly to managing internal forces generated within such systems. Background technique [0004] Injectable medications are usually administered through the use of a needle attached to a syringe. The needle is manually inserted into the patient's tissue, and the plunger is manually displaced to eject the drug from the reservoir into the patient. Self-administering medications using a syringe can be cumbersome and / or uncomfortable for some patients, particularly those with little or no experience with handling a syringe. Therefore, patients often use automatic injection systems to assist with injections. Such systems typically provi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/20A61M5/315A61M5/142A61M5/32
CPCA61M5/14248A61M5/2033A61M2005/2013A61M2005/2086A61M5/2046A61M5/2053A61M5/31585A61M2005/31588A61M2005/3267A61M5/31568A61M2005/208A61M5/3157
Inventor C·普兰贝克M·梅兰德
Owner AMGEN INC
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