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Bioactive glass hydrocolloid dressing for promoting wound healing

A technology of bioactive glass and wound healing, applied in viscous dressings, dressings, medical science, etc.

Active Publication Date: 2021-05-18
温州医科大学慈溪生物医药研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Currently, there is no report of a novel hydrocolloid dressing that promotes wound healing in which bioactive glass and sanggenone G are simultaneously added

Method used

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  • Bioactive glass hydrocolloid dressing for promoting wound healing
  • Bioactive glass hydrocolloid dressing for promoting wound healing
  • Bioactive glass hydrocolloid dressing for promoting wound healing

Examples

Experimental program
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Effect test

Embodiment 1

[0040] A bioactive glass hydrocolloid dressing for promoting wound healing, which is composed of a backing layer, a drug-containing colloid layer and an anti-adhesive layer, and the drug-containing colloid layer is composed of the following components in parts by weight:

[0041]

[0042] The bioactive glass consists of Na 2 O, CaO, P 2 o 5 and SiO 2 Composition, and the weight percentage is 24.5wt%: 24.5wt%: 6wt%: 45wt%, the particle size is 50 μm; the backing layer is polyurethane film, and the release layer is silicone oil paper.

Embodiment 2

[0044] A bioactive glass hydrocolloid dressing for promoting wound healing, which is composed of a backing layer, a drug-containing colloid layer and an anti-adhesive layer, and the drug-containing colloid layer is composed of the following components in parts by weight:

[0045]

[0046]

[0047] The bioactive glass consists of Na 2 O, CaO, P 2 o 5 and SiO 2 Composition, and the weight percentage is 24.5wt%: 24.5wt%: 6wt%: 45wt%, the particle size is 50 μm; the backing layer is polyurethane film, and the release layer is silicone oil paper.

Embodiment 3

[0049] A bioactive glass hydrocolloid dressing for promoting wound healing, which is composed of a backing layer, a drug-containing colloid layer and an anti-adhesive layer, and the drug-containing colloid layer is composed of the following components in parts by weight:

[0050] bioactive glass 10 copies Sangenone G 5 copies Styrene-isoprene-styrene triblock copolymer 40 copies C5 petroleum resin 35 copies polyisobutylene 35 copies 2,6-di-tert-butylcresol 2 copies carboxymethyl cellulose 50 copies citric acid 2 copies

[0051] The bioactive glass consists of Na 2 O, CaO, P 2 o 5 and SiO 2 Composition, and the weight percentage is 24.5wt%: 24.5wt%: 6wt%: 45wt%, the particle size is 50 μm; the backing layer is polyurethane film, and the release layer is silicone oil paper.

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Abstract

The invention relates to a bioactive glass hydrocolloid dressing for promoting wound healing and a preparation method and application thereof. The hydrocolloid dressing consists of a backing layer, a drug-containing colloid layer and an anti-sticking layer; the drug-containing colloid layer consists of a thermoplastic elastomer, tackifying resin, a plasticizer, an antioxidant, a water-absorbent colloid, acidic particles, bioactive glass and sanggenone G; and the bioactive glass consists of Na2O, CaO, P2O5 and SiO2, and the particle size is 40-60 [mu]m. The drug-containing bioactive glass hydrocolloid dressing of the invention has excellent adhesion performance, drug release performance and high water absorption capacity; the function of promoting wound healing and wound repair of the hydrocolloid dressing can be greatly enhanced; and the dressing is convenient to use, high in stability, low in irritation, and is especially suitable for treating chronic ulcerative wounds such as diabetic ulcers, diabetic feet and bedsores.

Description

technical field [0001] The invention belongs to the technical field of wound bioactive dressings, and in particular relates to a bioactive glass hydrocolloid dressing for promoting wound healing and its preparation method and application. Background technique [0002] The management of ulcerative wounds plays a vital role in the healing process of chronic ulcerative wounds such as diabetic ulcers, diabetic feet or decubitus ulcers. Current treatments for chronic ulcerative wounds mainly include debridement, skin grafting, vacuum sealing drainage, anti-infection, local active factors, stem cell transplantation, and functional dressing coverage. Appropriate wound dressings can provide a good microenvironment for the wound and promote its healing. Hydrocolloid dressing is a medical material made by uniformly mixing hydrocolloid particles with rubber substrate. The material combines the water-absorbing properties of hydrocolloid particles with the adhesive properties of a rubb...

Claims

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Application Information

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IPC IPC(8): A61F13/02A61L15/18A61L15/20A61L15/24A61L15/26A61L15/28A61L15/34A61L15/44A61L15/46
CPCA61F13/0213A61F13/0289A61F13/00051A61F13/00063A61L15/18A61L15/20A61L15/24A61L15/34A61L15/28A61L15/26A61L15/44A61L15/46A61L2300/112A61L2300/216A61L2300/412A61L2300/404A61L2300/41C08L53/02C08L75/04
Inventor 孔晓霞张宏宇肖健夏卫东许可
Owner 温州医科大学慈溪生物医药研究院
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