A multi-station high-throughput pipetting device
A high-throughput, multi-station technology, applied in the direction of measuring tubes/pipettes, laboratory utensils, laboratory containers, etc., can solve the problem of pipette sleeve and pipette tip insertion failure Low, skewed pipetting components and other problems, to achieve good insertion effect and high work efficiency
Active Publication Date: 2022-07-22
GUANGXI TECHCAL COLLEGE OF MACHINERY & ELECTRICITY
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Problems solved by technology
Since the assembly of the pipette handle and the pipette tip is an interference fit, the pipette handle of the pipetting assembly will be subjected to very large resistance when inserting pipette tips in large quantities, and this assembly resistance will be transmitted to the supporting pipette. The support mechanism of the liquid assembly, especially when the rigidity of the support mechanism is poor, the support mechanism of the pipetting assembly will be greatly deformed, causing the pipetting assembly to be skewed, affecting the insertion effect of some pipetting tips, resulting in partial displacement Failed to insert the liquid sleeve handle and pipette tip
In addition, the loading plate of this utility model has only two stations, and the box needs to be changed manually during work, which is a semi-manual operation and the work efficiency is low
Method used
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[0048] The structure of the multi-station high-throughput pipetting device according to the embodiment of the present invention is as follows: Figure 1 to Figure 20 As shown, it includes a base 02 , an X-axis drive mechanism 10 , a Y-axis drive mechanism 20 , a Z-axis drive mechanism 30 , a pipette head 100 and two rows of pipetting instruments 200 . The pipette head 100 includes a pipetting mechanism and an insertion mechanism. Each column of pipettes 200 includes a pipette tip holder 90 , a liquid sample holder 95 and a tube holder 96 .
[0049] The Y-axis driving mechanism 20 includes a linear module, and the linear module of the Y-axis driving mechanism 20 is installed on the base 02 along the Y-axis direction. It includes a housing 21 , a Y-axis motor 22 , a synchronous belt transmission device, a driving block 23 and two sets of linear guide rail pairs 24 . The driving block 23 is arranged above the strip-shaped housing 21 and is a hollow structure, including two side ...
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The invention discloses a multi-station high-throughput pipetting device. The base includes three stations along the Y-axis direction, the first station includes a first pipetting tip placement box, and the second station includes a first Liquid sample box, the third station includes a test tube placement box, when the pipette tip is assembled with the pipette sleeve handle, the insertion mechanism drives the pipetting mechanism to descend, and the sleeve handle of the pipetting assembly is inserted into the inner hole of the pipette tip After the middle, the inserting mechanism grabs the box body of the tip placement box, further exerts pressure on the pipetting mechanism, and press-fits the pipette sleeve handle at the lower part of the pipetting assembly into the inner hole of the pipetting tip. The downward pressing force of the pipetting assembly of the present invention is balanced by the pulling force applied by the insertion mechanism to the tip placement box, and will not be transmitted to the bearing mechanism of the pipetting device to deform the bearing mechanism. Good; there are three stations along the Y-axis, no need to manually change the box when pipetting, and the pipetting work efficiency is high.
Description
[Technical field] [0001] The invention relates to a liquid pipetting device, in particular to a multi-station high-throughput liquid transfer device. [Background technique] [0002] Pipetting is an important operation in biology, medicine and other fields, and it is one of the basic operations of various research experiments. In the work involving pipetting and titration, pipette guns are mostly used. Most of the process of taking and discharging liquid of these instruments relies on manual operation, which is prone to problems such as leakage of liquid and forgetting to rinse. [0003] Automatic pipetting equipment is an automated liquid handling instrument that can replace traditional pipetting tools, and can automatically complete high-precision liquid handling tasks such as gradient dilution, pipetting, and combining liquids. Efficient and accurate detection of substances. The fully automated operation process of the multi-station high-throughput automatic pipetting eq...
Claims
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IPC IPC(8): B01L3/02
CPCB01L3/0227B01L3/0234B01L3/0293
Inventor 黄增廖剑斌苏茜李华川余小榕邓桂丹
Owner GUANGXI TECHCAL COLLEGE OF MACHINERY & ELECTRICITY