This invention relates to a method for modifying the surface of biomaterials with an ultrathin hydrophilic lubricating
coating and its application. The method comprises: mixing
plasma-treated biomaterials with a precursor solution and performing an in-situ
polymerization reaction to obtain biomaterials with an ultrathin hydrophilic lubricating
coating; the precursor solution includes
dopamine or its salt, zwitterionic monomers, and
Tris buffer. The ultrathin hydrophilic lubricating
coating prepared by the method of this invention can reduce the
friction coefficient of
biomaterial surfaces and has strong hydrophilic
lubrication properties; it can form ultrathin hydrophilic lubricating coatings on the surfaces of different biomaterials, is suitable for
surface modification of most biomaterials, has a simple and easy process, good hydrophilic
lubrication properties, and can effectively improve the surface
lubrication performance of biomedical materials.