Tissue compensation membrane generation method and tissue compensation membrane

Abstract

The invention provides a tissue compensation membrane generation method and a tissue compensation membrane. The tissue compensation membrane generation method comprises the following steps: S1, obtaining an initial tissue compensation membrane based on patient image information; S2, performing dose distribution optimization on the currently obtained tissue compensation membrane to obtain optimal planned dose distribution; S3, adjusting the currently obtained tissue compensation membrane based on the planned dose distribution to obtain an adjusted tissue compensation membrane; S4, executing the step S2, judging whether a dose distribution result meets a prescription requirement or not, if yes, skipping to the step S5, and if not, continuing to execute the step S3; and S5, generating the tissue compensation membrane. According to the method, an objective optimization algorithm and objective evaluation indexes are adopted to replace manual experience, so that a better tissue compensator shape can be generated according to specific cases, and clinical benefit of a patient is improved.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to a method for forming a tissue compensation film and the tissue compensation film. Background technique [0002] In recent years, the incidence of tumors has been increasing, and radiotherapy, as the three main means of tumor treatment, has been widely used in clinic. With the development of intensity modulated technology, the precise control of radiation dose is one of the core contents of modern radiation therapy. However, due to the various particles used in radiotherapy: photons / electron rays / protons / heavy ions, etc., there is a dose building effect, which will cause problems such as insufficient dose in the target area in superficial tumors, or excessive dose in the skin. Radiation therapy tissue compensators are often used at this time to increase the dose of radiation to the superficial target area. [0003] At present, more tissue compensators are used clinically, which ...

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Problems solved by technology

[0005] 1. At present, the most commonly used tissue compensator in clinical practice is a square silica gel equivalent tissue compensator with a certain thickness. However, due to its fixed shape, there are many shortcomings in the process of use. First, the human body surface is often an irregular curved surface, so The fit between the tissue compensator and the body surface is not good, and the existence of the air gap can significantly reduce the surface dose, and narrowing the air gap can improve the dose uniformity of the target area and improve the accuracy of radiotherapy. For irregular body surfaces, it is usually used clinically Self-made millet flour bags, paraffin, wet gauze, vaseline (gauze), etc. are used to fill the gaps, but there are defects such as rough workmanship, poor conformity, poor tissue uniformity, and poor repeatability, which makes the actual radiation dose of superficial lesions very large. Second, the thickness of commercially available tissue compensation materials cannot be changed, and it is difficult to meet clinical requirements. For example, patients with postoperative adjuvant radiotherapy for breast cancer may need to use tissues with different thicknesses between 3mm and 10mm. Third, breast cancer patients in some special cases, such as patients who need breast skin irradiation after breast conserving surgery, also need special devices with positioning and compensation functions to assist

[0006] 2. In recent years, tissue compensation membranes based on 3D printing have only been improved in the production method. The specific thickness still needs to be drawn manually by the doctor, and the optimization algorithm of dosimetry has not been used for objective evaluation.

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