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Low-dose cerebral perfusion CT reconstruction method based on prior image constraint diffusion tensor

A prior image constraint, diffusion tensor technology, applied in the field of low-dose cerebral perfusion CT reconstruction, can solve the problems of inconsistent intensity values, reduced precision, affecting the accuracy of cerebral hemodynamic parameters, etc., to achieve high-quality reconstruction and reduce noise. and artifact effects

Inactive Publication Date: 2021-08-17
GANNAN NORMAL UNIV
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Problems solved by technology

Since the intensity values ​​of the prior image and the low-dose cerebral perfusion CT target image are inconsistent, the difference between the two images will cause a large error between the reconstructed image and the target image
When there is a big difference between the intensity values ​​of the prior image and the image to be reconstructed, the pseudo lesion information in the prior image will be introduced into the reconstructed image finally obtained by the above-mentioned prior image-guided cerebral perfusion CT image reconstruction method, resulting in the distortion of the image reconstruction. Reduced precision, which in turn affects the accuracy of cerebral hemodynamic parameter estimation

Method used

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  • Low-dose cerebral perfusion CT reconstruction method based on prior image constraint diffusion tensor
  • Low-dose cerebral perfusion CT reconstruction method based on prior image constraint diffusion tensor
  • Low-dose cerebral perfusion CT reconstruction method based on prior image constraint diffusion tensor

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Embodiment 1

[0082] A low-dose cerebral perfusion CT reconstruction method based on a priori image-constrained diffusion tensor, such as figure 1 , including steps are:

[0083] Include steps are:

[0084] Step 1. Obtain the system parameters of the cerebral perfusion CT equipment, the plain scan image and the original projection data under the low-dose scanning protocol;

[0085] Step 2. Perform system correction and logarithmic change on the original projection data sequence obtained in step 1 to obtain projection data, and estimate the variance of the projection data according to the system parameters in step 1 to obtain the projection data variance;

[0086] Step 3, using the plain scan image obtained in step 1 as a priori image, and constructing a priori image constrained diffusion tensor based on the plain scan image and the target image to be reconstructed;

[0087] Step 4. According to the variance of the projection data obtained in step 2, the prior image-constrained diffusion t...

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Abstract

According to a low-dose cerebral perfusion CT reconstruction method based on the prior image constraint diffusion tensor, a cerebral hemodynamic parameter image is obtained through the six steps. According to the method, geometric structure features of a high-quality prior image are introduced into a low-dose cerebral perfusion CT reconstruction process, and noise and artifacts can be effectively reduced while key features of a target image can be kept. According to the method, the problem that large errors exist between the reconstructed image and the target image due to the fact that the intensity values of the prior image and the low-dose cerebral perfusion CT target image are inconsistent is solved, and high-quality reconstruction of the low-dose cerebral perfusion CT image is achieved.

Description

technical field [0001] The invention relates to the technical field of medical image reconstruction, in particular to a low-dose cerebral perfusion CT reconstruction method based on a priori image-constrained diffusion tensor. Background technique [0002] Cerebral perfusion CT imaging can quickly, accurately and non-invasively obtain three-dimensional cerebral blood flow parameters. However, cerebral perfusion CT examination requires continuous dynamic volume scanning of the brain, resulting in an extremely increased X-ray radiation dose compared with conventional CT examination. Aiming at the X-ray radiation dose problem in the process of cerebral perfusion CT examination, the World Health Organization, the International Commission on Radiology and the International Organization for Medical Physics have formulated X-ray radiation dose control standards, and strongly advocated that cerebral perfusion CT examination should follow the principles of practical legitimacy and opt...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T11/00
CPCG06T11/006G06T2211/421G06T2211/424
Inventor 牛善洲李楠刘沛沄刘汉明汪廷华喻高航马建华
Owner GANNAN NORMAL UNIV
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