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A compound traditional Chinese medicine for preventing and treating atrial fibrillation

A technology of atrial fibrillation and compound traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve the problems of arrhythmia side effects, high price, high recurrence rate, etc., and achieve the effect of inhibiting liver wind, low recurrence rate, and smooth Qi movement

Active Publication Date: 2022-03-01
桂珍生物科技(辽宁)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the treatment of atrial fibrillation in Western medicine mainly includes rhythm control (including antiarrhythmic drug therapy and cardioversion, radiofrequency ablation and other non-drug treatments), ventricular rate control (taking β-blockers, non-dihydropyridine calcium ion antagonists, digoxin and amiodarone, etc.), prevention of thromboembolism and stroke caused by atrial fibrillation, upstream treatment of atrial fibrillation and surgical treatment of atrial fibrillation, etc., but the above drugs have many adverse reactions, and although they can Anti-arrhythmia, but it also has arrhythmogenic side effects at the same time, and the commonly used Western medicine treatment methods such as radiofrequency ablation technology are expensive, and there is a high recurrence rate, and can cause myocardial burns, so the current Western medicine for atrial fibrillation Treatment is a double-edged sword, and Western medicine treatment of atrial fibrillation is at a bottleneck

Method used

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  • A compound traditional Chinese medicine for preventing and treating atrial fibrillation
  • A compound traditional Chinese medicine for preventing and treating atrial fibrillation
  • A compound traditional Chinese medicine for preventing and treating atrial fibrillation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The following raw materials are used to prepare the compound Chinese medicine for preventing and treating atrial fibrillation:

[0028] 15g tangerine peel, 10g pinellia, 10g bamboo rut, 10g citrus aurantium, 10g baicalin, 10g bupleurum, 10g white peony root, 10g roasted licorice, 15g sophora flavescens, 10g sweet pine, 5g silkworm, 10g mulberry root, 15g salvia miltiorrhiza, cooked Panax notoginseng 2g, cassia twig 6g, keel 25g and oyster 25g.

[0029] The preparation method comprises the following steps:

[0030] Weigh and mix the decoction pieces of each raw material, crush to obtain mixed Chinese medicine powder, add 15 times the weight of water, soak for 40 minutes, decoct with strong fire for 70 minutes, pour out the liquid medicine; then add 10 times the weight of water for decoction After 50 minutes, pour out the medicinal solution; then add 5 times the weight of water and decoct for 30 minutes, pour out the medicinal solution; combine the medicinal solutions ob...

Embodiment 2

[0032] The following raw materials are used to prepare the compound Chinese medicine for preventing and treating atrial fibrillation:

[0033] 10g tangerine peel, 5g pinellia, 15g bamboo, 5g aurantium, 15g baicalin, 5g bupleurum, 15g white peony, 5g roasted licorice, 20g flavescens, 5g sweet pine, 8g silkworm, 5g mulberry, 20g salvia, cooked Panax notoginseng 1g, cassia twig 9g, keel 20g and oyster 30g.

[0034] The preparation method comprises the following steps:

[0035] Weigh and mix the decoction pieces of each raw material, crush to obtain mixed Chinese medicine powder, add 15 times the weight of water, soak for 30 minutes, decoct with strong fire for 60 minutes, pour out the liquid medicine; then add 10 times the weight of water for decoction After 40 minutes, pour out the liquid medicine; then add 5 times the weight of water and decoct for 30 minutes, pour out the liquid medicine; combine the liquid medicine obtained from the three times, filter with gauze, and concen...

Embodiment 3

[0037] The following raw materials are used to prepare the compound Chinese medicine for preventing and treating atrial fibrillation:

[0038] 20g tangerine peel, 15g pinellia, 5g bamboo rut, 15g citrus aurantii, 5g baicalin, 15g bupleurum, 5g white peony, 15g roasted licorice, 10g sophora, 15g sweet pine, 2g silkworm, 15g mulberry, 10g salvia, cooked Panax notoginseng 5g, cassia twig 3g, keel 30g and oyster 20g.

[0039] The preparation method steps are as follows:

[0040]Weigh and mix the decoction pieces of each raw material, crush to obtain mixed Chinese medicine powder, add 15 times the weight of water, soak for 40 minutes, decoct with strong fire for 70 minutes, pour out the liquid medicine; then add 10 times the weight of water for decoction After 40 minutes, pour out the liquid medicine; then add 5 times the weight of water and decoct for 20 minutes, pour out the liquid medicine; combine the liquid medicine obtained from the three times, filter with gauze, and concen...

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Abstract

The invention discloses a compound Chinese medicine for preventing and treating atrial fibrillation, which belongs to the technical field of traditional Chinese medicine; the raw materials of the compound Chinese medicine include tangerine peel, pinellia, bamboo rutabaga, citrus aurantium, scutellaria baicalensis, Bupleurum radix, Radix Paeoniae Alba, roasted licorice, flavescens, Gansong, silkworm, mulberry, salvia, cooked notoginseng, cassia twig, keel and oyster; the compound Chinese medicine of the present invention can inhibit the occurrence and development of atrial fibrillation from multiple channels and multiple targets, and can improve the autonomic nervous system of atrial fibrillation. Activation, oxidative stress, fibrosis and prethrombotic state have good therapeutic effects on atrial fibrillation of phlegm and blood stasis type, can significantly improve the frequency and duration of atrial fibrillation, and the clinical effective rate is as high as 86%; and adopt the present invention The recurrence rate of atrial fibrillation treated by the compound Chinese medicine is low, and the three-month conversion maintenance rate is 80%; meanwhile, the compound Chinese medicine of the present invention is used to treat atrial fibrillation without obvious toxic and side effects and adverse reactions.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a compound traditional Chinese medicine for preventing and treating atrial fibrillation. Background technique [0002] Atrial fibrillation ("AF" for short, Atrial Fibrillation) is the most common clinical arrhythmia, which refers to the loss of regular and orderly atrial electrical activity and is replaced by rapid and disorderly fibrillation waves, which is the most serious atrial electrical activity disorder. Atrial disordered fibrillation loses effective contraction and relaxation, atrial pump function deteriorates or loses, and atrioventricular node decreases conduction of rapid atrial excitation, causing extremely irregular ventricular response. Therefore, ventricular rhythm disorder, impaired cardiac function, and atrial wall thrombosis are the main pathological characteristics of patients with atrial fibrillation. Faster ventricular rate af...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P9/06A61K35/02A61K35/618A61K35/64
CPCA61K36/752A61K36/8888A61K36/899A61K36/539A61K36/233A61K36/71A61K36/65A61K36/484A61K36/489A61K36/84A61K35/64A61K36/185A61K36/537A61K36/258A61K36/54A61K35/02A61K35/618A61P9/06A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00
Inventor 宫丽鸿
Owner 桂珍生物科技(辽宁)有限公司
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