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Whitening and bacteriostatic white mulberry root-bark extract as well as preparation method and application thereof

A technology of Cortex Morus alba extract and Cortex Morus albicans, applied in skin care preparations, medical preparations containing active ingredients, skin diseases, etc., can solve problems such as the stability of Cortex Morus alba extract that has not been paid attention to, and achieve biological The content of active ingredients and their effects can enhance, dilute melanin, and have good whitening and antibacterial effects

Active Publication Date: 2021-11-26
山东花物堂生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the above-mentioned method, the stability of the cortex Morus alba extract is not paid attention to
[0006]Therefore, there is no Morus alba extract with good stability and better whitening, antibacterial and antiseptic activity in the prior art

Method used

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  • Whitening and bacteriostatic white mulberry root-bark extract as well as preparation method and application thereof
  • Whitening and bacteriostatic white mulberry root-bark extract as well as preparation method and application thereof
  • Whitening and bacteriostatic white mulberry root-bark extract as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] This embodiment provides a kind of preparation method of the Cortex Morus alba extract that is used for cosmetics, and concrete steps are as follows:

[0047] In the first step, the dry Cortex Morus alba 400 mesh is selected and pulverized to obtain Cortex Morus alba powder;

[0048]The second step is to weigh 500g of Cortex Mori powder, add 4000g of ethanol with a mass concentration of 75% to carry out an alcohol extraction, and heat and reflux extraction at a temperature of 90°C for 3 hours to obtain a primary alcohol extract of Cortex Mori. After the end, add Stir 120g of activated carbon evenly, place it in a water bath at 80°C for decolorization for 60 minutes, and filter while it is hot to remove the activated carbon;

[0049] In the third step, the Cortex Morus alba filtrate is subjected to primary molecular distillation and secondary molecular distillation successively under the assistance of microwaves, and the light fractions of molecular distillation are comb...

Embodiment 2

[0058] This embodiment provides a kind of preparation method of the Cortex Morus alba extract that is used for cosmetics, and concrete steps are as follows:

[0059] In the first step, the dry Cortex Morus alba is selected and pulverized to obtain Cortex Morus alba powder;

[0060] The second step is to weigh 500g of Cortex Mori powder, add 5000g of ethanol with a mass concentration of 75% to carry out an alcohol extraction, and heat and reflux extraction at a temperature of 70°C for 4 hours to obtain a primary alcohol extract of Cortex Mori. After the end, add Stir 120g of activated carbon evenly, place it in a water bath at 70°C for 45 minutes to decolorize, and filter while it is hot to remove the activated carbon;

[0061] In the third step, the Cortex Morus alba filtrate is subjected to primary molecular distillation and secondary molecular distillation successively under the assistance of microwaves, and the light fractions of molecular distillation are combined to obtai...

Embodiment 3

[0070] This embodiment provides a kind of preparation method of the Cortex Morus alba extract that is used for cosmetics, and concrete steps are as follows:

[0071] In the first step, the dry Cortex Morus alba is selected and pulverized to obtain Cortex Morus alba powder;

[0072] The second step is to weigh 500g of Cortex Mori powder, add 3000g of ethanol with a mass concentration of 90% to carry out an alcohol extraction, heat and reflux extraction at a temperature of 80°C for 3.5 hours, and obtain a primary alcohol extract of Cortex Mori. After the end, add Stir 100g of activated carbon evenly, place it in a water bath at 90°C for 30 minutes to decolorize, and filter while it is hot to remove the activated carbon;

[0073] In the third step, the Cortex Morus alba filtrate is subjected to primary molecular distillation and secondary molecular distillation successively under the assistance of microwaves, and the light fractions of molecular distillation are combined to obtai...

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Abstract

The invention discloses a preparation method of a white mulberry root-bark extract. The preparation method comprises the following steps of 1, carrying out primary alcohol extraction on white mulberry root-bark by using ethanol to obtain a white mulberry root-bark primary alcohol extract, decolorizing, and filtering to obtain white mulberry root-bark filtrate; 2, sequentially carrying out first-stage molecular distillation and second-stage molecular distillation on the white mulberry root-bark filtrate, and combining light fractions of molecular distillation to obtain white mulberry root-bark molecular distillate; 3, carrying out vacuum suction filtration on the white mulberry root-bark molecular distillate by using a diatomite cake, carrying out secondary alcohol extraction to obtain a white mulberry root-bark secondary alcohol extract, and carrying out rotary evaporation concentration to obtain a white mulberry root-bark concentrate; and 4, pretreating the white mulberry root-bark concentrate, carrying out vacuum suction filtration, adding 1, 3 propylene glycol, and compounding until the total weight during pretreatment is reached, so as to obtain the white mulberry root-bark extract. The white mulberry root-bark extracting solution prepared by the invention has good stability, can effectively reduce melanin in skin and effectively inhibit abnormal reproduction of propionibacterium acnes, has good corrosion resistance, and can be used for preparing cosmetics with related effects.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a whitening and antibacterial Morus alba extract, a preparation method thereof, and an application thereof in cosmetics. Background technique [0002] Morus alba is the dry root bark of the dicotyledonous plant Mulberry meridian after removing the cork. It was first recorded in "Shen Nong's Herbal Classic". In traditional Chinese medicine, Morus alba is sweet and cold in nature, and returns to the lung and spleen meridian. Antihypertensive, anticancer and liver protection effects. Recently, with the in-depth research on the chemical composition and pharmacological activity of Cortex Morus alba, people have a deeper understanding of the main components of Cortex Morus alba, and found that Cortex Morus albicans extract contains TYR (tyrosinase ) active main ingredient - Sanggenone C, which contains flavonoids with good antioxidant capacity and certain ingredients that inhibit ac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61Q19/02A61Q17/00A61P31/04A61P17/10
CPCA61K8/9789A61Q19/02A61Q17/005A61P31/04A61P17/10A61K2800/81A61K2800/805A61K2800/524Y02A50/30
Inventor 朱士强梅华倩亓云吉
Owner 山东花物堂生物科技有限公司
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