Application of oral bacterial liquid carrier

Abstract

The invention discloses application of an oral bacterial liquid carrier, and belongs to the technical field of micro-ecology and biomics detection. The invention discloses application of an oral bacterial liquid carrier. The oral bacterial liquid carrier is placed in the oral cavity overnight under a sterile condition, and oral bacterial liquid is extracted, wherein the oral bacterial liquid carrier comprises any substance capable of utilizing the sulcus vestibularis of the oral cavity. The oral bacterial liquid carrier is used for extracting the oral bacterial liquid to research oral micro-ecology, and releasing related flora metabolites to adjust the oral micro-ecology. The oral bacterial liquid carrier can absorb original ecology saliva in the oral cavity, and through a series of biomics technologies, including metagenomics, proteomics, transcriptomics and the like, the original ecology composition characteristics of the oral cavity can be found, a relation between oral-cavity and whole-body related diseases and the oral micro-ecology is further explored, in addition, the oral cavity original ecology environment can be manually intervened through the oral bacterial liquid carrier, and a new target spot is provided for oral cavity health care and whole-body related disease treatment.

Description

technical field [0001] The invention relates to the technical field of microecology and bio-omics detection, in particular to the application of an oral bacterial liquid carrier. Background technique [0002] Microorganisms exist in every corner of human life and affect every aspect of human life. The human oral cavity contains habitats for many different microorganisms. There are about 50-100 billion bacteria in the oral cavity of an adult, of which more than 200 species account for the main part. Each species in the oral cavity affects the health and disease of the host through the interaction with the host. The synergy and interaction of various oral microorganisms can help the human body resist the invasion of external adverse stimuli. However, oral microorganisms also play an important role in the initiation and deterioration of certain diseases. At this time, the oral microecological balance is broken, and pathogenic bacteria, especially facultative anaerobic bacter...

AI Technical Summary

Problems solved by technology

[0003] At present, clinical methods to study the oral micro-ecosystem include dental plaque, mouthwash, saliva collector and other methods, but these methods have certain limitations

For example, collecting saliva with a saliva collector or using mouthwash, because the oral exposure of the subjects is likely to affect the oral micro-ecological environment, and the final research results are easily affected by the oral saliva secretion conditions of the saliva donor, so it cannot reflect the real situation objectively and accurately. Oral micro-ecological conditions; the local internal environment of dental plaque and the composition of the flora are relatively stable, which can better reflect the micro-ecological conditions of the oral cavity, so it is widely used in clinical trials, but the supply of dental plaque is relatively small, which is of great importance to dental plaque. The requirements for extraction technology are relatively high, which greatly limits the follow-up further research

It can be seen that the diversity and instability of the extraction methods of oral flora will lead to the inaccuracy and confusion of information extraction.

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