Facial cream composition containing lipidosome with anti-aging effect as well as preparation method and application of facial cream composition

A liposome and composition technology, applied in the field of daily chemicals, can solve the problems of skin metabolism disorder, low skin barrier function, human skin damage, etc., to resist skin aging and relaxation, strengthen skin barrier, and reduce peroxidative damage Effect

Active Publication Date: 2022-01-07
湖北省麦诗特生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, my own irregular life and lack of sleep lead to disordered skin metabolism, which will also cause accelerated aging of the skin, loss of elasticity and sagging and sagging; at the same time, when the daily pressure increases, the tissue of the human skin will be destroyed and decomposed, followed by Causes a decrease in skin barrier function
[0004] Although we can reduce skin aging caused by external factors through some protective measures, it will still cause damage to human skin more or less

Method used

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  • Facial cream composition containing lipidosome with anti-aging effect as well as preparation method and application of facial cream composition
  • Facial cream composition containing lipidosome with anti-aging effect as well as preparation method and application of facial cream composition
  • Facial cream composition containing lipidosome with anti-aging effect as well as preparation method and application of facial cream composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0058] A face cream composition comprising liposomes with anti-aging effect, made into an anti-aging face cream, the proportion and content of its raw material components are shown in Table 1 below.

[0059] The raw material component distribution ratio (unit: mass %) of table 1 embodiment 1-3

[0060]

[0061] The preparation process of the face cream composition containing the anti-aging effect liposome of the above-mentioned embodiment 1 comprises the following steps:

[0062] 1) Preparation of anti-aging effect liposome a: Weigh 400 mg of hexapeptide-11, 800 mg of Dunaliella salina extract, 800 mg of Fleischer's willow leaf extract, and 800 mg of Gynostemma pentaphyllum extract at pH= Dissolve in the phosphate buffer solution of 6.8 by ultrasonic; weigh 1000mg of phospholipid and 200mg of cholesterol, dissolve in ether and dissolve by ultrasonic; pour the phosphate buffer solution into ether, homogenize at 15000r / min for 5min, remove at room temperature Organic solvent...

Embodiment 1

[0087] Test sample: embodiment 1;

[0088] Test method: Use a third-party testing agency to test the safety. Select an area not exceeding 50mm 2 , with a suitable patch device with a depth of about 1mm, add about 0.02-0.025ml (g) of the test substance to the patch test device in a closed patch test method. Stick the spot tester on the curved side of the forearm of the subject, remove the test substance after 24 hours, observe the skin reaction at 0.5h, 24h, and 48h after removal, and record the results according to the skin reaction classification standard in "Cosmetic Safety Technical Regulations 2015" .

[0089] Table 2 Patch test results

[0090]

[0091] Remarks: Skin reaction grading standard

[0092] Level 0: Negative reaction;

[0093] Grade 1: Suspicious reaction; only faint erythema;

[0094] Grade 2: Weak positive reaction (erythema reaction); erythema, infiltration, edema, papules may be present;

[0095] Grade 3: strong positive reaction (herpes reaction)...

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Abstract

The invention discloses a facial cream composition containing lipidosome with an anti-aging effect and a preparation method of the facial cream composition. The facial cream composition is prepared from the following raw material components of 0.1 to 15 percent of lipidosome with an anti-aging effect, 1 to 30 percent of a humectant, 1 to 22.5 percent of an emollient, 1 to 21 percent of an emulsifying agent, 0.1 to 10 percent of a filling agent, 1 to 12.5 percent of a thickening agent, 0.1 to 3.5 percent of a preservative, 0.01 to 1 percent of a pH regulator, 0.01 to 1 percent of daily essence and the balance of de-ionized water. The main components of the lipidosome with the anti-aging effect comprise hexapeptide-11, a dunaliella salina extract, an epilobium fleischeri extract and a fiveleaf gynostemma herb extract. By compounding the components at the same time, synthesis of skin collagen can be increased, the activity of superoxide dismutase is enhanced, excessive free radicals in skin are removed, peroxidation damage of tissue or cells is relieved, skin barrier is enhanced, and skin structure is strengthened to resist skin aging and relaxation.

Description

technical field [0001] The invention relates to a skin care product and its preparation method and application, belonging to the technical field of daily chemicals, and more specifically relates to a face cream composition containing anti-aging liposomes, its preparation method and application. Background technique [0002] Nowadays, anti-aging has become the most concerned point in everyone's skin care process. The earlier you start skin care, the more youthful your skin can be maintained for a long time. Under normal circumstances, we can feel the gradual aging of the skin when we are 25 years old. The skin damage caused by skin aging is difficult to restore the original appearance. Only by early skin care and delaying the arrival of aging can we effectively improve the aging effect. Sagging skin, fine lines around the eyes, dull complexion, etc. [0003] In addition to the gradual aging of the skin, there are also some external factors that will accelerate its aging, suc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/9722A61K8/64A61K8/14A61K8/55A61K8/63A61K8/34A61Q19/08
CPCA61K8/9789A61K8/9722A61K8/64A61K8/553A61K8/63A61K8/345A61K8/14A61Q19/08A61K2800/5922A61K2800/522A61K2800/84Y02A50/30
Inventor 李宗厚杨帆周紫燕李沫郭苗周正
Owner 湖北省麦诗特生物科技有限公司
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