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A kind of Gansu capsule and preparation method thereof

A technology of Gansu capsules and capsule shells, which can be used in capsule delivery, pharmaceutical formulations, and medical preparations of non-active ingredients. Time of action, lowering enzymes and protecting the liver, good effect

Active Publication Date: 2022-07-05
ZHEJIANG WECOME MEDICINE IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the existing Gansu capsules, the Gansu capsule particles are packed into the capsule shell, and the Gansu capsules are used to treat hepatitis. After the Gansu capsule shell is absorbed and dissolved by the gastric mucosa, the Gansu capsule particles will all dissolve into the gastric juice , is absorbed by the gastric mucosa, and then acts on the human liver, but all Gansu capsule particles are dissolved in the gastric juice at the same time, and the drug effect will not be fully absorbed by the gastric mucosa, which may cause a part of the drug effect to be lost, so that the drug effect cannot be absorbed. It is completely absorbed, and the effective solution of the existing technology is coating technology. The surface of the drug particles is covered with films of different thicknesses to make the drug continuously dissolve, and the drug is administered uniformly so that the drug effect can be fully absorbed by the human body. However, the drug The particles are small, and different drug particles are coated to different degrees, and the production process is more complicated

Method used

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  • A kind of Gansu capsule and preparation method thereof
  • A kind of Gansu capsule and preparation method thereof
  • A kind of Gansu capsule and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0030] The preparation method of Gansu Capsules is as follows: take 5556g of root vegetables, chop them, add water and cook for three times for 2 hours each time, then combine the decoctions, filter the decoctions, and concentrate the filtrate to a relative density of about 1.15-1.1860℃-65 ℃ clear paste, let it cool, add ethanol to make the alcohol content reach 60%, then stir, let stand for 22 hours, filter, wash the precipitate with 60% ethanol three times, combine the washing liquid and filtrate, and recover the ethanol under reduced pressure until there is no alcohol taste, concentrated to a clear paste with a relative density of 1.0880°C, spray-dried, added silicon dioxide and talc to make Gansu granules or powder, dried, packed into capsule shells, and made into 1000 capsules.

[0031] The color of Gansu granules produced by this method is brown to tan powder or granules, slightly bitter and astringent in taste, mainly used for reducing enzymes, protecting liver, reducing...

Embodiment 2

[0033] see Figure 1-5 , a Gansu capsule, comprising a capsule shell and Gansu granules contained in the capsule shell. The capsule shell includes a capsule shell 1 , a sustained release structure 2 and Gansu granules 3 . The capsule shell 1 includes an upper shell 11 and a lower shell 12 , and the inner wall of the upper shell 11 is clamped with the outer wall of the lower shell 12 .

[0034] The sustained-release structure 2 is installed in the lower shell 12, the lower shell 12 is dissolved in gastric juice, and the Gansu granules 3 are placed in the sustained-release structure 2. The sustained-release structure 2 is used to gradually release the medicinal effect of the Gansu granules 3. The sustained-release structure 2 includes Including three charging frames 21, the three charging frames 21 have the same structure, the outer wall of the charging frame 16 is in contact with the inner wall of the lower shell 12, so that the capsule structure is compact, and the air exists ...

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Abstract

The invention relates to the field of capsules, and discloses a Gansu capsule, which comprises a capsule shell and Gansu granules contained in the capsule shell; the Gansu granules include a plaster of root vegetables, silicon dioxide and talcum powder. Get a suitable weight of root vegetables and chop them, add water and boil N times, then combine the decoction and filter, filter and concentrate to clear paste, add ethanol to obtain a mixed solution, leave it for a period of time, filter to obtain a precipitate, after the precipitate is washed with ethanol M times, merge Washing liquid and filtrate, recovering ethanol under reduced pressure until no alcohol smell and concentrating to clear paste, spray drying to obtain Zhagencai clear paste; the capsule shell includes capsule shell and slow-release structure, and the slow-release structure is used to hold Gansu granules, and the slow-release The structure is installed inside the capsule shell, a floating sheet is arranged on the outer side wall of the upper shell, and a sinker is arranged on the inner bottom wall of the lower shell. Liver, for chronic active hepatitis, hepatitis B.

Description

technical field [0001] The invention relates to the field of capsules, in particular to a Gansu capsule and a preparation method thereof. Background technique [0002] Drugs in capsules are generally powders or granules that are irritating to the esophagus and gastric mucosa, or drugs that have a bad taste, are easily volatile, are easily decomposed by saliva in the oral cavity, and are easily inhaled into the trachea. These medicines are packed into capsules, which not only protect the medicinal properties of the medicines from being destroyed, but also protect the digestive organs and respiratory tract. [0003] However, in the existing Gansu Capsule, the Gansu Capsule granules are put into the capsule shell, and the Gansu Capsule is used to treat hepatitis. After the Gansu Capsule shell is absorbed and dissolved by the gastric mucosa, all the Gansu Capsule particles will dissolve into the gastric juice. , absorbed by the gastric mucosa, and then acts on the human liver, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/52A61K36/185A61K47/04A61K47/02A61P1/16A61J3/07
CPCA61K36/185A61K9/1611A61P1/16A61J3/071A61K2236/331A61K2236/55A61K2236/51Y02A50/30
Inventor 吴建明丁京伟
Owner ZHEJIANG WECOME MEDICINE IND
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