Method for de-noising electron microscope image
An electron microscope and image technology, applied in the field of sample analysis, can solve problems such as artifacts and affecting the accuracy of measurement indicators
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[0074] figure 1 Shown are steps of a method for denoising an electron microscope (EM) image according to an embodiment.
[0075] Method 10 includes the step of selecting a patch of an 11EM image, wherein the patch includes a plurality of pixels. Subsequently, the following steps i)-iii) are performed on the patch:
[0076] i) replacing the value of one pixel of the patch, preferably the central pixel, with the value of a different, preferably randomly selected, pixel from the same EM image;
[0077] ii) determining 14 the denoising value of the one pixel based on the values of the other pixels in the patch; and
[0078] iii) Substitute the value of 15 for the one pixel with the determined denoised value.
[0079] In particular, steps i) to iii) form a denoising 12 step for this one pixel in the patch.
[0080] In particular, steps i) to iii) may be repeated for each pixel in the selected patch until every noisy pixel within the patch is replaced by a denoised value.
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