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Degradable antibacterial coating for knee joint pad

An antibacterial coating, knee joint technology, applied in coating, medical science, prosthesis and other directions, to reduce bacterial infection, reduce volatilization rate, anti-allergic blood circulation effect

Pending Publication Date: 2022-04-12
FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, many current coatings fail to achieve good antibacterial properties and in vivo degradation properties at the same time

Method used

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Embodiment

[0016] This example discloses a degradable antibacterial coating for knee joint pads, which includes the following components in parts by mass: 40-60 parts of polyazlactone, 40-60 parts of dopamine, 35 parts of volatile oil aromatic compounds -55 parts, 20-30 parts of mugwort extract, 15-25 parts of adhesive agent; the volatile oil aromatic compound includes crape myrtle volatile oil aromatic compound, lily of the valley volatile oil aromatic compound and rose volatile oil aromatic compound, crape myrtle volatile oil aromatic compound, The mass ratio of the aromatic compound of lily of the valley volatile oil and the aromatic compound of rose volatile oil is 1:1:1; the adhesive agent is chitosan and sodium alginate, and the mass ratio of chitosan and sodium alginate is 1:1. The main raw materials used in this embodiment are vegetable raw materials, which are degradable and environmentally friendly. Artemisia mugwort has a wide range of sources, and has the functions of antibac...

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PUM

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Abstract

The invention relates to the technical field of medical antibacterial coatings, and discloses a degradable antibacterial coating for a knee joint pad, which comprises polyazlactone, dopamine, a volatile oil aromatic compound, a mugwort extract and an adhesive. The material disclosed by the invention is natural, environment-friendly, degradable and durable, has the effects of resisting bacteria, diminishing inflammation, resisting allergy and promoting blood circulation, not only achieves the antibacterial effect, but also can promote the recovery of a joint replacement part, and has good adhesion; according to the invention, the volatile oil aromatic compound and the adhesive are separately used and used for treating the knee joint pad, so that the coating disclosed by the invention is sequentially coated in multiple layers from inside to outside, the outermost layer has a bactericidal effect, and the volatile oil aromatic compound and the mugwort extract in the middle layer have antibacterial and bactericidal effects; the coating provided by the invention has sterilization and antibacterial effects from inside to outside, and through multi-layer coating, the thickness and coating rate of the coating layer can be improved, the volatilization rate of related components is reduced, and the component utilization rate is improved.

Description

technical field [0001] The invention relates to the technical field of medical antibacterial coatings, in particular to a degradable antibacterial coating for knee joint pads. Background technique [0002] With the aging of modern society and the accelerated pace of life, the number of patients with orthopedic injuries has increased sharply. Total knee replacement is an effective measure for the treatment of severe osteoarthritis and related diseases. According to statistics, there are more than 2 million artificial prosthesis replacement cases worldwide every year. example. Infection is one of the most serious complications after artificial joint replacement. Staphylococcus is the most common strain of artificial joint replacement infection, accounting for 70% to 80%. Bacterial infection of orthopedic implants and internal fixation devices can lead to catastrophic complications. It is a very difficult problem in current orthopedic treatment and rehabilitation. It not only ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/34A61L27/54A61L27/58
Inventor 李想王铖崔翔唐佩福柴伟郝立波李春宝付君徐驰
Owner FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA
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