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R-band chromosome karyotype image identification method and system based on grouping information assistance

A chromosome karyotype and image recognition technology, applied in the field of R-band chromosome karyotype image recognition method and system, can solve the problems of less research work and patents, and achieve the effect of process introduction, great application prospect, and increased reliability.

Pending Publication Date: 2022-05-27
SHANGHAI JIAO TONG UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] For the image recognition of R-banded chromosomes, there are few existing research works and patents

Method used

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  • R-band chromosome karyotype image identification method and system based on grouping information assistance
  • R-band chromosome karyotype image identification method and system based on grouping information assistance
  • R-band chromosome karyotype image identification method and system based on grouping information assistance

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Embodiment Construction

[0044] The present invention will be described in detail below with reference to specific embodiments. The following examples will help those skilled in the art to further understand the present invention, but do not limit the present invention in any form. It should be noted that, for those skilled in the art, several modifications and improvements can be made without departing from the concept of the present invention. These all belong to the protection scope of the present invention.

[0045] Aiming at the features of the R-band chromosome karyotype image and the problems existing in the existing identification methods, the present invention provides an embodiment of an R-band chromosome karyotype image identification method assisted based on grouping information. In this embodiment, two auxiliary tasks of chromosome length grouping and centromere position grouping are used to assist the feature extraction process of the main task of chromosome identification, so as to imp...

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Abstract

The invention provides an R-band chromosome karyotype image identification method based on grouping information assistance. The method comprises the following steps: obtaining a chromosome image; performing normalization processing on the chromosome image; a dyeing identification model is constructed, the chromosome identification model takes chromosome length grouping and centroid position grouping as auxiliary tasks, and chromosome identification is taken as a main task; training the chromosome recognition model; and using the trained chromosome identification model to predict the category. According to the method, the analysis efficiency of the karyotype is effectively improved, automatic classification and sorting of the chromosomes are accurately completed, the process is simple, and the method has a relatively great application prospect.

Description

technical field [0001] The invention relates to the field of chromosomal karyotype image processing, in particular, to a method and system for identifying an R-band chromosomal karyotype image assisted based on grouping information. Background technique [0002] The karyotype is an important tool for the diagnosis of various hematological malignancies and genetic diseases. Human somatic cells have a total of 23 pairs of chromosomes, including 22 pairs of autosomes (1-22) and a pair of sex chromosomes (female XX, male XY), a total of 24 types. The most distinctive features that cytogeneticists use to distinguish different types of chromosomes are the length of the chromosomes, the location of the centromeres, and the order of dark and light bands. Commonly used chromosomal banding techniques are Giemsa (G)-, Reverse (R)- and centromere (C)-banding. Compared with G-banding, R-banding showed poor chromosomal morphology. However, some abnormalities that occur at the ends of c...

Claims

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Application Information

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IPC IPC(8): G06V20/69G06V10/80G06V10/764G06V10/82G06K9/62
CPCG06N3/04G06N3/08G06F18/2414G06F18/253
Inventor 杨杰夏朝陈冰王霁月
Owner SHANGHAI JIAO TONG UNIV
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