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Compound gel preparation as well as preparation method, administration mode and application thereof

A gel preparation and compound technology, which is applied in the field of compound gel preparations, can solve the problems of strong drug dependence and failure to achieve the goal of radical treatment, and achieve the effects of improving therapeutic effect, improving local blood supply, and increasing concentration

Pending Publication Date: 2022-06-21
四川中天鑫源生命科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Based on this, it is necessary to provide a compound gel preparation and its preparation method, administration method, and application for the current oral drug treatment of erectile dysfunction, which is highly dependent on drugs and cannot achieve the goal of radical cure.

Method used

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  • Compound gel preparation as well as preparation method, administration mode and application thereof
  • Compound gel preparation as well as preparation method, administration mode and application thereof
  • Compound gel preparation as well as preparation method, administration mode and application thereof

Examples

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Effect test

Embodiment 1

[0032] S24 Continue to centrifuge the centrifuged supernatant, and discard 70% to 90% of the volume of the supernatant, and mix the precipitate with the remaining supernatant to obtain a concentrated umbilical cord mesenchymal stem cell exosome.

[0033] Put the recovered centrifuge supernatant into a centrifuge tube, centrifuge for 30-60min under the condition of 200000-500000g centrifugal force, take out the centrifuge tube gently after centrifugation, use a pipette to discard 70%-90% volume of the supernatant The remaining 10% to 30% of the volume of the liquid and the sediment at the bottom of the centrifuge tube were uniformly mixed, and used as the raw material for preparing the preparation for erectile dysfunction, that is, the umbilical cord mesenchymal stem cell exosome concentrate.

[0034] S3 Add ginsenoside Rb, yohimbine hydrochloride, pharmaceutical polymer stabilizer (sodium hyaluronate), moisturizer (propylene glycol and glycerin) and dimethyl sulfoxide, mixed t...

Embodiment 2

experiment example 1

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Abstract

The invention discloses a compound gel preparation as well as a preparation method, an administration mode and application thereof. The preparation method comprises the following steps: S1, selecting human umbilical cord mesenchymal stem cells, and providing ginsenoside Rb, yohimbine hydrochloride, a medicinal polymer stabilizer, a humectant and dimethyl sulfoxide; s2, performing starvation culture-enrichment concentration on the human umbilical cord mesenchymal stem cells to obtain an umbilical cord mesenchymal stem cell exosome concentrated solution. And S3, sequentially adding ginsenoside Rb, yohimbine hydrochloride, a medicinal polymer stabilizer, a humectant and dimethyl sulfoxide into the umbilical cord mesenchymal stem cell exosome concentrated solution, and mixing to obtain the compound gel preparation. According to the present invention, the human umbilical cord mesenchymal exosome extract can be obtained within a short time, the recovery efficiency is significantly improved, the recovery mode is simple and convenient, and the compound gel preparation having the significant treatment effect on erectile dysfunction can be prepared.

Description

technical field [0001] The present invention relates to a gel preparation, in particular to a compound gel preparation, and also relates to a preparation method, administration mode and application of the compound gel preparation. Background technique [0002] Erectile dysfunction (erectile dysfunction, ED) is the most common male dysfunction disease, which mainly manifests as the inability to achieve and maintain an erection for satisfactory sexual intercourse, and the course of the disease lasts for more than 3 months. ED is generally divided into organic, surgical, traumatic, mental, and penile lesions. The conventional treatment method is oral drug therapy, but this treatment method is highly dependent on drugs and cannot achieve the goal of a radical cure. Contents of the invention [0003] Based on this, it is necessary to provide a compound gel preparation and its preparation method, administration method and application for the current oral drug treatment of erecti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K35/28A61K31/704A61K31/475A61K47/20A61K47/10A61P15/10A61P15/08
CPCA61K9/06A61K9/0034A61K35/28A61K31/704A61K31/475A61K47/20A61K47/10A61P15/10A61P15/08A61K2300/00
Inventor 邹莉
Owner 四川中天鑫源生命科技有限公司
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