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Method for modifying surface of titanium dental implant and titanium dental implant

A dental implant and surface modification technology, which is applied in prosthetics, dentistry, dental implants, etc., can solve the problems of long dental implant bone tissue, complicated preparation process, and high energy consumption, so as to improve osseointegration ability , promote cell proliferation, and promote osteogenic differentiation

Active Publication Date: 2022-07-29
SICHUAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In order to solve the above problems, the present invention provides a method for surface modification of titanium dental implants and titanium dental implants. The surface of titanium dental implants is modified by magnesium-strontium double-doped micro-nano modification, which can effectively solve the problems in the prior art. It takes a long time for the dental implant to osseointegrate with the alveolar bone, and it is difficult for the dental implant to be tightly integrated with the bone tissue in the early stage of implantation, and the surface modification method of the titanium dental implant in the prior art is costly and difficult to prepare. Problems such as complex process and high energy consumption

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  • Method for modifying surface of titanium dental implant and titanium dental implant
  • Method for modifying surface of titanium dental implant and titanium dental implant
  • Method for modifying surface of titanium dental implant and titanium dental implant

Examples

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Embodiment 1

[0052] In Example 1, titanium nails were selected as the base material for surface modification of titanium dental implants, which were easily implanted into the medullary cavity of rat tibia, and the osseointegration ability was tested.

[0053] (1) Put the titanium nail into a PTFE liner containing a mixed solution of 14wt% hydrogen peroxide and 2wt% phosphoric acid, and seal it for 24h at 0.15MPa and 120°C; Dry at room temperature for 24 hours to obtain a micro-nano titanium phosphate / titanium hybrid coating.

[0054] (2) The titanium nails with the micro-nano titanium phosphate / titanium mixed coating obtained in step (1) are soaked in a polytetrafluoroethylene liner containing a mixed solution of 1wt% strontium chloride and 1wt% magnesium chloride, and hydrothermally It was placed in an autoclave, sealed and stored at 100° C. for 8 hours to obtain a magnesium-strontium double-doped micro-nano surface-modified titanium nail.

[0055] Electron microscope scanning analysis w...

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Abstract

The invention provides a surface modification method of a titanium dental implant and the titanium dental implant. The surface modification method comprises the following steps: step 1, preparing a micro-nano titanium phosphate / titanium mixed coating on the surface of the titanium dental implant; 2, magnesium ions and strontium ions are doped to the surface of the titanium dental implant with the micro-nano titanium phosphate / titanium mixed coating formed on the surface at the same time through a hydrothermal method, and the magnesium-strontium double-doped micro-nano surface modified titanium dental implant is obtained. The surface of the dental implant is subjected to magnesium-strontium double-doped micro-nano surface modification, so that cell adhesion of BMSCs is increased, proliferation and osteogenic differentiation of the BMSCs are promoted, and the bone combining capacity of the dental implant can be improved in multiple directions. In addition, the surface modification method also has the characteristics of low cost, simplicity and easiness in operation, high reaction rate and the like. The magnesium-strontium double-doped micro-nano surface modified titanium dental implant obtained by adopting the method effectively solves the problems that the time required for bone combination of the dental implant and an alveolar bone is long, and the dental implant is difficult to be tightly combined with a bone tissue in the early stage of implantation.

Description

technical field [0001] The invention relates to the field of titanium dental implants, in particular to a method for surface modification of titanium dental implants. Background technique [0002] Denture defect is a common disease in the field of stomatology, and implant denture restoration is the best treatment method to solve dentition defect. The implant part of the implant denture is a structure that is implanted into the bone tissue to replace the natural root. Currently, the implants used clinically are mainly root-shaped structures made of titanium and titanium alloys, which have good physical and chemical properties. The cementum and alveolar bone on the root surface of natural teeth are connected by a layer of periodontal ligament. The periodontal ligament is a kind of fibrous connective tissue. One end of its main fibers is embedded in the cementum, and the other end is embedded in the alveolar bone, which fixes the tooth in the alveolar socket. It also has prote...

Claims

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Application Information

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IPC IPC(8): A61L27/06A61L27/30A61L27/32C23C22/54A61C8/00
CPCA61C8/0015A61L27/06A61L27/32A61L27/306C23C22/54A61L2430/12A61L2300/102A61L2300/412Y02P10/25
Inventor 杨文宾郭子荐张洁包琬琳扈宁
Owner SICHUAN UNIV
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