105 results about "Strontium ions" patented technology

The invention provides a mineralization composition as well as a preparation method and application thereof. The mineralization composition comprises modified celestite, modified strontium-containing dolomite, modified medical stone, modified zeolite, modified tourmaline, modified wollastonite and modified serpentine. The strontium ion dissolution amount of the modified celestite is 50 to 55 mg / L; the strontium ion dissolution amount of the modified strontium-containing dolomite is 15 to 20 mg / L; the metasilicate ion dissolution amount of the modified medical stone is 30 to 35 mg / L; the metasilicate ion dissolution amount of the modified zeolite is 40 to 45 mg / L; the metasilicate ion dissolution amount of the modified tourmaline is 3 to 5 mg / L; the dissolution amount of metasilicate ions in the modified wollastonite is 3 to 5 mg / L; the dissolution amount of metasilicate ions in the modified serpentine is 10 to 15 mg / L. The mineralization composition can stably and enduringly release strontium ions and metasilicate ions, and also can adjust the water quality to alkalescence, so that the water quality reaches the national drinking water standard, and safe and healthy drinking water can be provided for users.

The invention provides a composite hydrogel for infectious bone defect repair and a preparation method thereof, and belongs to the technical field of bone defect repair, the composite hydrogel comprises a three-dimensional porous network structure hydrogel and a bioactive unit, and the bioactive unit is loaded in the three-dimensional porous network structure hydrogel; the hydrogel with the three-dimensional porous network structure is prepared from photo-crosslinked methacrylated silk fibroin and nano-hydroxyapatite; the bioactive unit comprises a strontium metal organic framework loaded with curcumin. According to the invention, the photo-crosslinked methacrylated silk fibroin provides excellent biocompatibility; as an ion / drug dual carrier, the strontium metal organic framework can continuously release strontium ions and bidirectionally regulate bone metabolism (promoting osteogenesis and inhibiting osteoclast), and the porous structure of the strontium metal organic framework can efficiently load a hydrophobic drug curcumin (Cur). Curcumin has strong antibacterial and anti-inflammatory functions; the nano-hydroxyapatite can obviously enhance the mechanical strength of the hydrogel.

The composition is of a network structure and is composed of strontium ions and chlorogenic acid, and the weight ratio of the strontium ions to the chlorogenic acid is 1: (9-11). The composition and hydrogel are mixed to prepare a microneedle patch, and the microneedle patch is prepared into a medical instrument for wound repair. Through verification, the SrC-MPNs is continuously released by the SrC-MPNs (at) MN-PP, so that the substances are dissolved and absorbed into tissue fluid around a wound, and strontium ions and chlorogenic acid in the SrC-MPN can stably and continuously exert the effects of resisting bacteria and oxidation, promoting angiogenesis, promoting wound healing and the like. An in-vivo experiment result shows that the SrC-MPNs (at) MN-PP can promote in-vivo and in-vitro wound healing, promote M2 macrophage polarization, remove excessive ROS and promote angiogenesis and tissue regeneration so as to promote healing of diabetic wounds.

The invention belongs to the technical field of biomimetic materials, and discloses a titanium alloy implant surface biomimetic coating and a preparation method thereof.The biomimetic coating comprises a porous titanium support layer, a micron-sized porous titanium layer is prepared through plasma spraying, and then nano-hydroxyapatite is doped to improve osteoinductivity; the graphene enhancement layer is modified, a graphene oxide film is electrochemically deposited, the graphene oxide film and the titanium substrate are covalently bonded through a silane coupling agent, and strontium ions are loaded to promote osteogenic differentiation; an antibacterial active layer and in-situ reduced graphene oxide form a three-dimensional network conductive structure, tantalum-doped carbon nitride quantum dots are loaded through ultrasonic dispersion and embedded between graphene layers to form an antibacterial phase, and then magnesium silicate nanowires are subjected to hydrothermal growth to form a bioactive phase. Through triple bionic design of porous titanium, ion release / photo-thermal response and PDA adhesion, the bone bonding strength, antibacterial property, wear resistance and corrosion resistance of a coating interface are improved.

The invention discloses an injectable multifunctional intelligent response type strontium-containing hydrogel microsphere as well as a preparation method and application thereof, the strontium-containing hydrogel microsphere comprises a hydrogel microsphere carrier and a loaded medicine, and the hydrogel microsphere is obtained from lycium barbarum polysaccharide and a temperature-sensitive polymer through a microfluidic technology; the loaded medicine is strontium ions and a near-infrared light conversion material, the strontium ions are combined with the lycium barbarum polysaccharide in the microspheres through ion coordination, and the near-infrared light conversion material is combined with the microspheres through physical adsorption. The lycium barbarum polysaccharide and the temperature-sensitive polymer are combined, the bone regeneration promoting capacity is improved through the synergistic effect of the lycium barbarum polysaccharide and the temperature-sensitive polymer, the hydrogel microspheres have intelligent adjustability further through the near-infrared response performance, the strategic purpose of individualized drug delivery in time and space is achieved, and the application prospect is wide. The limitation that a hydrogel carrier cannot be administrated according to needs is avoided, and the hydrogel carrier is small in particle size, injectable and convenient in administration.

The invention relates to the technical field of fuel cell new materials and new energy, in particular to an A-site high-entropy perovskite cathode material and a preparation method thereof. According to the technical scheme, the material comprises the following raw materials: Pr (NO3) 3.6 H2O, La (NO3) 3.6 H2O, Co (NO3) 2.6 H2O, CaCO3, BaCO3, SrCO3 and citric acid. The molar ratio of the praseodymium ions to the lanthanum ions to the cobalt ions to the calcium ions to the barium ions to the strontium ions to the citric acid is 1: (1-2). According to the invention, the A site of the perovskite material is doped with a plurality of elements, a rapid quenching preparation process is combined, the oxygen vacancy concentration and the proton conduction path can be optimized, the ORR activity and the conductivity can be improved, and excellent electrochemical performance and thermal stability can be shown through the synergistic effect of the plurality of elements and structural regulation and control, so that the performance of the cell can be improved.

The invention belongs to the technical field of medical biomaterial engineering application, and particularly relates to a bone repair scaffold for promoting diabetic bone defect repair. The stent main body is provided with a functional material, and the functional material comprises one or a combination of more than two of the following components: platelet-derived growth factors, copper ions and strontium ions; the weight part ratio of the platelet-derived growth factor to the copper ions to the strontium ions is (0.001-0.1): (0.005-1): (0.01-10). According to the bone repair scaffold provided by the invention, through the synergistic effect of the platelet-derived growth factor (PDGF-BB) and trace metal copper and strontium, the bone defect and osteoporotic bone defect of a diabetic patient are treated.

The invention provides a positive electrode electrolyte, a preparation method of the positive electrode electrolyte and a flow battery, the positive electrode electrolyte comprises: an active material suitable for providing positive pentavalent vanadium ions; a dispersant; the cations comprise at least one of calcium ions, magnesium ions, sodium ions, barium ions, strontium ions and ammonium ions; and chloride ions. Therefore, the positive electrode electrolyte has relatively good stability, the solubility and the dispersity of positive pentavalent vanadium ions in the positive electrode electrolyte can be improved, precipitation is avoided, and the capacity and the energy density of the battery are further improved.

The invention discloses a strontium ion adsorbent and a preparation method thereof.The preparation method comprises the steps that cation exchange resin reacts with calcium hydroxide suspension / water-soluble calcium salt aqueous solution, so that calcium ions are loaded on the cation exchange resin in an ion exchange mode, and the cation exchange resin loaded with the calcium ions is obtained for use; and suspending the obtained cation exchange resin loaded with calcium ions in deionized water, then adding a mixed solution of phosphate and alkali into the system, forming hydroxyapatite precipitate in the resin and loading hydroxyapatite crystals in the cation exchange resin to obtain the spherical beaded strontium ion adsorbent. The hydroxyapatite-loaded resin provided by the invention has high-selectivity adsorption on strontium ions in a solution, and can remove the strontium ions with high selectivity in the presence of a large number of coexisting cations.

A preparation method and application of an iron-gold / oxygen-deficient strontium titanate one-dimensional hollow nanotube composite photocatalyst, which relates to a preparation method and application of a photocatalyst. The present invention is to solve the problem that the prior art prepares a strontium titanate-based composite photocatalyst with low photogenerated carrier separation efficiency and lacks methane adsorption sites and catalytic active centers for activating oxidants. In the present invention, strontium ions in strontium nitrate are first coordinated with a complexing agent acetylacetone to form a strontium acetylacetonate intermediate, and then reacted with tetrabutyl titanate to form a strontium titanate precursor, and then the precursor solution is electrostatically spun in combination with subsequent calcination treatment to form a strontium titanate one-dimensional hollow nanotube, and then a sodium borohydride vacuum hydrogen reduction treatment is performed to obtain a strontium titanate one-dimensional hollow nanotube with surface oxygen defects, and finally a step-by-step freezing photoreduction method is used to induce metal gold and iron to be modified on the surface of oxygen-deficient strontium carbonate to obtain an iron-gold / oxygen-deficient strontium titanate one-dimensional hollow nanotube composite photocatalyst.

The present invention relates to a preparation method of a barium strontium sulfate descaling agent, comprising the following steps: adding a prepared additive solution to a prepared chelating agent alkaline solution, fully mixing and dissolving the solution, and adjusting the pH to alkaline, thereby obtaining the barium strontium sulfate descaling agent. The present invention has the following beneficial effects: the preparation method of the present invention can significantly improve the descaling effect of the descaling agent on barium strontium sulfate scale, increase the contact area with metal ions, thereby improving the overall descaling effect, effectively destroying the formation of barium strontium sulfate scale, and the descaling agent still maintains a stable descaling effect under high temperature conditions, and has broad industrial application prospects. The chelating agent used not only has good metal ion chelating effect, can effectively complex barium, strontium ions, and destroy the formation of barium sulfate and strontium sulfate crystals, but also has the characteristics of being stable under high temperature and high pH value, being suitable for complex industrial conditions, and performing well in neutral and alkaline water, and is also more environmentally friendly.

The invention discloses a wavelength selective photoresponse strontium-based metal organic framework eutectic material as well as a preparation method and application thereof. A metal node of the material is strontium ions, N, N '-bis (5-isophthalic acid) naphthalimide is used as a ligand, anthracene and a derivative thereof are used as objects, N, N-dimethylformamide is used as a solvent, and the material is obtained through solvothermal reaction. The material is composed of an electron donor (D) and an electron acceptor (A), and is a strontium-based MOF eutectic with an infinitely extended pi stacked A-D-D-A configuration. The MOF eutectic material has lattice characteristics of a tetragonal crystal system, a space group is I 41 / a, and cell parameters are a = b = 28.42240 (10), c = 13.71600 (10), and alpha = beta = gamma = 90 degrees. Sr-NDI at An has unique wavelength selective photoresponse property: ultraviolet light triggers [4 + 4] dimerization of an object anthracene, red light excites [4 + 2] reaction of anthracene and singlet oxygen, and near-infrared light induces generation of free radicals.

A kind of tin lead perovskite photodetector based on introducing guanidinium ion and strontium ion and preparation method thereof, belong to perovskite photoelectric device technical field.The photodetector described in the application is composed of ITO conductive glass anode, PTAA anode buffer layer, tin lead perovskite film introducing guanidinium ion and strontium ion, C 60 / BCP cathode buffer layer, Cu cathode from bottom to top. + When A-site cation is doped with ion in perovskite, the carrier lifetime of perovskite material can be improved, and the open-circuit voltage of the device can be improved, the carrier diffusion length can be increased, the defects can be reduced, and the stability of the device can be improved;Sr 2+ Doping with ion in B-site of perovskite can increase conductivity, improve stability and optimize electrode performance, ultimately achieve the effect of passivating defects, reducing the capture of electrons by traps and improving photoelectric conversion efficiency, and the optimization effect mainly reflects on light and dark current and external quantum efficiency, and a high-performance photodetector is obtained.

The present invention discloses a PP-BST 3‑x The invention relates to an implant and its preparation method and application, which belongs to the field of medical material technology. The invention constructs oxygen vacancies (BST) on the surface of strontium ion-doped barium titanate. 3‑x ), under ultrasonic conditions, the internal electron movement of the material is enhanced, making the electron-hole separation easier, thereby accelerating the reaction of electrons with surrounding substances and improving the efficiency of ROS generation. And the PP-BST prepared by the present invention 3‑x On the one hand, the implant can polarize macrophages through electrical potential and inhibit inflammation; on the other hand, it can regulate Sr release through ultrasound, thereby inhibiting osteoclast differentiation in an infected environment, achieving dual-pathway osteogenesis, and improving the high osteoclast environment brought about by the bacterial microenvironment while inhibiting bacteria, thereby promoting bone regeneration, accelerating bone healing ability, and reducing patient recovery time.

The invention provides application of strontium ions in improving and / or promoting accumulation of tanshinone components and / or salvianolic acid components, and belongs to the technical field of hairy root induction. The invention provides application of strontium ions in improving and / or promoting accumulation of tanshinone components and / or salvianolic acid components. Salvia miltiorrhiza hairy roots are induced through different strontium ion concentrations, the influence of strontium ions on salvia miltiorrhiza quality components is researched, and a theoretical basis is expected to be provided for salvia miltiorrhiza quality improvement and strontium fertilizer development. The result of the embodiment shows that 10-100 [mu] mol / L of strontium ions are added in the salvia miltiorrhiza hairy root induction process, accumulation of tanshinone components and salvianolic acid components in the salvia miltiorrhiza hairy roots can be improved and promoted, and then the quality components of salvia miltiorrhiza can be improved.

This invention discloses a softening treatment device and method for high-temperature oilfield wastewater, relating to the field of wastewater treatment technology. Oilfield wastewater enters a pre-desorption tank for impurity removal. The barium-strontium adsorption tank contains, from top to bottom, a fine quartz sand layer, a chelating resin layer, and a coarse quartz sand layer. The silicate pre-desorption tank contains an acid-base regulator, a dispersant, and a magnesium oxide suspension. The carbonate softening tank contains a dispersant, a coagulant aid, a soda ash solution, and a chelating agent. The stabilizing tank contains, from top to bottom, a modified activated carbon layer and an exchange resin layer. This invention uses the pre-desorption tank to initially separate oil, suspended solids, and corrosion products. A specialized chelating resin selectively adsorbs barium-strontium ions. In the silicate pre-desorption tank, pH is precisely controlled and magnesium oxide is added to directionally generate settleable magnesium silicate flocs. In the carbonate softening tank, crystal form control and coagulation aid work synergistically to promote the precipitation of calcium and magnesium in the form of large calcite particles.

A coated nanocluster (10) comprises: a core (20) including an aggregate of magnesium oxide particles; and a shell (30) covering the core (20). The shell (30) has a coating layer (31) containing at least one of a nitrate and a nitrite, and carbonate particles (32) dispersed in the coating layer (31). At least one of the nitrate and the nitrite contains an alkali metal ion. The carbonate particles (32) contain at least one selected from a calcium ion, a strontium ion, and a barium ion. The molar ratio of the carbonate particles (32) constituting the shell (30) to the magnesium oxide particles constituting the core (20) is more than 0.005 and 0.015 or less.

The invention relates to the technical field of functional fertilizers, and discloses a heavy metal and insect disease double-effect regulation type organic fertilizer and a preparation process thereof, the fertilizer is a particle with a three-layer structure of core-inner layer coating-outer layer coating; the core is prepared from a composite passivation functional body, an organic nutrition matrix and a binder; the composite passivation functional body is a flavone-modified functional biological porous carrier loaded with strontium ion-doped nano-hydroxyapatite, and is used for fixing soil heavy metals and regulating and controlling rhizosphere micro-ecology; the inner-layer coating is prepared from wood vinegar, the outer-layer coating is prepared from chitosan oligosaccharide and sodium alginate, and the layered structure realizes sequential release of immune induction substances and synergistically induces plant resistance. Through specific structural design and component synergy, triple effects of heavy metal fixation, rhizosphere micro-ecological regulation and control and plant disease and insect pest induced resistance are achieved, and the effect is definite.

The invention is suitable for the technical field of oral implantology, and provides a preparation method and application of a 4D printing stent for simplifying oral bone increment surgery. According to the invention, a 4D printing technology is utilized, polydopamine and sodium alginate are mixed and printed into the hydrogel stent, and after strontium ion crosslinking, the stent shows excellent biodegradability and biocompatibility, can replace a titanium mesh bent stent, effectively maintains osteogenesis space, and reduces high technical sensitivity of an implant bone increment surgery. The stent can accurately adapt to different bone defect outlines, support is provided, healing is accelerated, and the risk of complications is reduced. The device is high in adaptability and easy and convenient to implant, unnecessary tissue stripping and injury can be reduced to the maximum extent, the operation duration is shortened, and postoperative recovery of a patient is facilitated. In a horizontal bone increment operation, the scaffold can provide a firm bone foundation for repair means such as subsequent tooth implantation and the like. A mechanical signal generated by deformation and bioactive components released by the stent have a synergistic effect, and bone tissue regeneration is accelerated.

To provide a carious tooth structure-restoring agent that is convenient for treating multiple teeth at once, and can be used for preventive treatment of root caries and for early caries treatment in an aesthetic manner without discoloring the treated area.SOLUTION: A carious tooth structure-restoring agent comprises: a compound (a) having an acidic group represented by the following formula (I): R1-Xk [in formula (I), R1 represents an organic group having 40 or less carbon atoms, which may or may not have at least one (meth)acryloyloxy group; X represents an acidic group; k represents an integer of 1 or 2; when k is 2, the two acidic groups X are the same as or different from each other]; a metal ion (b); water (c); and a hydrophilic solvent (d); and is substantially free of a crosslinkable polymerizable monomer. The metal ion (b) comprises at least one metal ion selected from the group consisting of a strontium ion (b1) and an aluminum ion (b2).SELECTED DRAWING: None

The application relates to a strontium mineralization filter element and a preparation method thereof and a water purifier. The strontium mineralization filter element comprises an inner layer and an outer layer arranged on the outer surface of the inner layer, the outer layer is used for being communicated with a water inlet, the inner layer is used for being communicated with a water outlet, the inner layer comprises silicate ore powder, and the outer layer comprises strontium ore powder; the mass ratio of the strontium ore powder to the silicate ore powder is 1-6:1. The strontium mineralization filter element can adjust the inhibition effect of silicate on the dissolution of strontium ions during the static state of the strontium mineralization filter element, so that the strontium ion concentration of the first cup of water after the strontium mineralization filter element is static can meet the safety upper limit requirement, and the strontium concentration of the produced water during the water passing period of the strontium mineralization filter element can meet the design lower limit requirement.

The present invention discloses a nitrogen mustard-synergistic strontium ion antibacterial fabric, as well as its preparation method and use. An azo drug, 4-(4-(bis(2-chloroethyl)amino)phenyl)diazenyl)-N-(3,4-dihydroxyphenylethyl)benzamide, is prepared using dopamine hydrochloride and N-phenyldiethanolamine. The drug is then coordinated with strontium ions on fabric fibers through in-situ growth to form nanoparticles. Upon contact with bacteria, the functionally coated fabric releases nitrogen mustard within the bacterial environment, forming a strong electrophilic alkylating agent within the cells. This covalently binds to electron-rich groups in DNA, RNA, and some enzymes, deactivating them and killing the bacteria. Furthermore, a large amount of strontium ions slowly released from the antibacterial fabric can be adsorbed on the surface of bacterial cell membranes, causing a voltage difference between the inside and outside of the cell membranes, weakening and rupturing the cell membranes. The strontium ions then enter the cells and hinder their formation and metabolism, thereby achieving a synergistic antibacterial effect.

The utility model relates to the technical field of scale prevention, in particular to scale prevention equipment in the evaporation process of drilling and production wastewater, which comprises a first primary hardness removal reaction chamber, a water inlet pipeline is fixedly connected to the left side surface of the first primary hardness removal reaction chamber, and a pipeline mixer is fixedly connected to the outer surface of the water inlet pipeline. The outer surface of the pipeline mixer is fixedly connected with an alkali liquor adding device. The device is reasonable in structure, related processes of deep hardness removal of phosphate and synergistic ammonia nitrogen removal are added on the basis of a dual-alkali process, scaling ions in the drilling and production wastewater can be more efficiently removed, meanwhile, the ammonia nitrogen concentration of produced water is reduced, the total hardness of the drilling and production wastewater treated by the device can be reduced from 1200-1500mg / L to below 20mg / L, and the treatment effect of the drilling and production wastewater is improved. The concentration of strontium ions is reduced from 60-80 mg / L to 30 mg / L or below, and the concentration of ammonia nitrogen is reduced from 30-40 mg / L to 15 mg / L or below, so that the scaling of the evaporator is effectively reduced, and meanwhile, the cooperative treatment of the ammonia nitrogen is realized.

This invention discloses a tetrachloroaluminate-modified type A molecular sieve, its preparation method, and its application. The invention uses fly ash cenospheres as the main raw material to prepare a type A molecular sieve. Through modification with a mixture of fly ash and tetrachloroaluminate, it exhibits excellent adsorption performance for cobalt, cesium, and strontium ions. The type A molecular sieve prepared in this application has a good synergistic effect with tetrachloroaluminate, effectively solving the problems of complex processes, high costs, and poor adhesion of existing molecular sieve adsorbent preparation methods in the market. 137 Cs, 60 Co, 90 This method addresses the problem of low adsorption rates of major hazardous nuclides in radioactive wastewater such as Sr, and can be used to adsorb radionuclides in nuclear wastewater.

The invention relates to the technical field of oral care products, in particular to an anti-acid repairing oral care composition, application thereof and an oral care product containing the composition. The anti-acid repairing oral care composition comprises strontium ions and a rhizoma drynariae extract, the preparation method comprises the following steps: mixing soluble strontium salt with water to obtain a strontium ion system; mixing the rhizoma drynariae extract with a humectant to obtain a rhizoma drynariae system; and mixing the strontium ion system and the rhizoma drynariae system, and performing ultrasonic treatment. The anti-acid repairing oral care composition can be applied to preparation of oral care products including toothpaste. According to the technical scheme, on the premise that potential allergens are prevented from being introduced and the stability of the product in the storage and use process is ensured, the bioavailability and the acting effect of strontium ions are effectively improved, and then the technical problem that the bioavailability and the acting effect of the strontium ions of the strontium-containing anti-acid repairing oral care product are limited is solved; and the method has ideal application and popularization prospects.

The invention discloses a preparation method and an application of a bone targeting catechin-strontium metal polyphenol nano particle. The system takes a metal-polyphenol network (MPN) formed by coordination self-assembly of strontium ions and catechin as a core, and tetracycline is modified on the surface of the MPN to construct a bone targeting functional layer. The MPN structure can significantly enhance the loading efficiency and physiological stability of catechin, and the tetracycline modification on the surface endows the nanoparticles with excellent bone targeting ability. When reaching an osteoporosis focus, the nanoparticles can respond to a local weakly acidic microenvironment and controllably release catechin, and exert antioxidant and anti-inflammatory effects, thereby reversing a pathological microenvironment unfavorable for bone regeneration. Meanwhile, the MPN skeleton is gradually degraded in vivo, and the released Sr < 2 + > can promote proliferation and differentiation of pre-osteogenic cells, inhibit the activity of osteoclasts and promote formation of new bones. The system integrates bone targeting, microenvironment response drug release, immunoregulation and ion regulation treatment, and provides a new strategy for precise treatment of osteoporosis.

The invention relates to the technical field of biomedical materials, and discloses a bioglass / polycaprolactone stent as well as a preparation method and application thereof. The bioglass / polycaprolactone scaffold is prepared from the following raw materials: polycaprolactone, strontium-doped bioglass, a dopamine solution and a solvent I. According to the bioglass / polycaprolactone scaffold provided by the invention, through the unique collaborative design of a strontium-doped bioglass mesoporous structure and a polydopamine intelligent coating, precise controlled release and immune-osteogenesis dual-function regulation of strontium ions are realized, and the scaffold has excellent mechanical properties (the compressive strength is about 22.5 MPa) and an ideal pore structure (the porosity is about 60%); due to the polydopamine coating, the surface of the stent achieves super hydrophilicity (the contact angle is 0 degree), and cell adhesion and proliferation can be remarkably promoted; the scaffold can synchronously induce polarization of macrophages to M2 type and promote osteogenic differentiation, and solves the key problems of strong hydrophobicity and single function of the traditional scaffold.

The invention belongs to the technical field of water treatment, particularly relates to the field of G21F9 / 06, and more particularly relates to a treatment method of saline water containing strontium ions. According to the method, carbon dioxide is mainly used as a flocculating agent and can replace sodium carbonate commonly used in a traditional process, compared with a traditional strontium ion removal process, the process is more environmentally friendly, the treatment cost can be effectively reduced, meanwhile, the removal rate of strontium ions in saline water can reach 98% or above, and the excellent strontium ion removal effect is achieved.

The invention belongs to the technical field of crystals, and particularly relates to a method for preparing calcium fluoride crystals with high laser damage resistance through a Czochralski method. The crystal is a calcium fluoride crystal doped with strontium ions and trace lithium ions, and the maximum laser damage threshold of the crystal can reach 4.7 J / cm < 2 >. The preparation of the crystal is characterized in that gradient temperature control is carried out on the basis of a traditional Czochralski method, temperature distribution of a melt-crystal interface and a surrounding area is regulated and controlled, and the key problems of solid-liquid interface stability, stress control, component uniformity and the like in the crystal growth process are solved.

The application discloses a preparation method of a near-beta TLM titanium alloy dealloying / chronological functional surface, and the method comprises the following steps: 1, heat treatment to obtain a dual-phase microstructure TLM titanium alloy substrate; 2, electrochemical dealloying to obtain a hierarchical micro-nano porous surface structure; 3, preparation of a complex solution; 4, chemical deposition of the complex solution to construct an osteogenesis and vascularization functional layer on the hierarchical micro-nano porous surface structure; and 5, electrostatic adsorption to construct an antibacterial functional layer. The osteogenesis and vascularization functional layer and the antibacterial functional layer are introduced on the dealloyed surface of the TLM titanium alloy, the surface is endowed with the chronological expression characteristics through controllable degradation release, the positive electricity and the porous structure of polylysine are used to realize synergistic antibiosis, the tannic acid induced strontium ion controllable release improves the osteogenesis and vascularization performance, the hierarchical micro-nano porous structure of the surface is beneficial to the formation of good bone bonding, the TLM titanium alloy is endowed with early antibiosis, medium and long-term osteogenesis promotion and excellent bone integration characteristics, and is used for bone defect repair.