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118results about How to "Simple and inexpensive method" patented technology

Oral delayed immediate release formulation and method for preparing the same

The invention relates to an Oral Delayed Immediate Release formulation comprising a compressed core containing one or more active substances surrounded with a coating, wherein release of active substance from the core is caused by rupture of the coating after a definite lag-time, said core comprising one or more immediate release carriers and having no substantial swelling properties upon exposure to gastrointestinal fluids. The invention further relates to formulations containing an Immediate Release formulation combined with one or more Oral Delayed Immediate Release formulations with different lag-times and to a method of preparing an Oral Delayed Immediate Release formulation.The Oral Delayed Immediate Release formulation may be used for the application of active substances whenever a certain lag-time before release is advantageous, such as in be the case of anti-asthmatics, anti-emetics, cardiotonics, vasodilators, anti-vertigo and anti-meniere compounds, anti-hypertensives, sedatives, anti-depressants, anti-anxiety compounds, cortico-steroids, general anti-inflammatory compounds, anti-inflammatory compounds for gastrointestinal use, anti-ulceratives, analgetics, anti-aritmics, anti-rheumatics, anti-arthritic compounds and anti-angina compounds.The Oral Delayed Immediate Release formulation may also be used for the application of biological active compounds such as proteins, peptides, enzymes, vaccines and oligonucleotides.
Owner:ABBOTT PROD OPERATION AG

Controlled release composition

InactiveUS20080254124A1Easy for to follow prescribed regimenConstant of releasePowder deliverySolution deliveryEthyl(hydroxyethyl)celluloseCellulose acetate
A composition for controlled delivery of at least one active substance into an aqueous medium by erosion at a preprogrammed rate of at least one surface of the composition, comprising a matrix comprising the active substance, the matrix being erodible in the aqueous medium in which the composition is to be used, and a coating having at least one opening exposing at least one surface of said matrix, the coating comprising a first cellulose derivative which has thermoplastic properties and which is substantially insoluble in the aqueous medium in which the composition is to be used, and at least one of a second cellulose derivative which is soluble or dispersible in water, a plasticizer, and a filler. The coating is a coating which crumbles and / or erodes upon exposure to the aqueous medium such as a body fluid. The first cellulose derivative may be, e.g., ethylcellulose, cellulose acetate, cellulose propionate or cellulose nitrate, and the second cellulose derivative may be, e.g. methylcellulose, carboxymethylcellulose or salts thereof, cellulose acetate phthalate, microcrystalline cellulose, ethylhydroxyethylcellulose, ethylmethylcellulose, hydroxyethylcellulose, hydroxyethylmethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxymethylcellulose or hydroxymethylpropylcellulose.
Owner:EGALET LTD

Method of estimating quantities that represent state of vehicle

A method is provided capable of improving the accuracy of estimations of quantities that represent the state of a vehicle, such as vehicle speed, wheel slip ratio, wheel speed along the ground, longitudinal wheel force and the vehicle body sideslip angle, or values related to the quantities that represent the vehicle state, using a simple and inexpensive method. A tire longitudinal force computing unit 81 calculates longitudinal forces F1 to F4 of each of the wheels by substituting a coefficient of friction μ, which is adjusted such that a deviation between a detected value of a longitudinal acceleration Gx and an estimated longitudinal acceleration Gxe is zero, an estimated vehicle speed Ve, slip ratios S1 to S4 of each of the wheels calculated based on detected values of sensors 11 and 31, loads W1 to W4 of each of the wheels, calculated based on detected values of sensors 12 and 61, and lateral forces Y1 to Y4, into an equation related to a predetermined tire dynamics model. A longitudinal acceleration estimating unit 82 calculates an estimated longitudinal acceleration Gxe based on the longitudinal forces F1 to F4 and a predetermined movement equation. An integrator 43 integrates with respect to time the estimated longitudinal acceleration Gxe, and calculates an estimated vehicle speed Ve.
Owner:HONDA MOTOR CO LTD
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