112results about How to "Limited effectiveness" patented technology

A switching power supply device may include a switching element for switching an input direct-current power, a smoothing section for smoothing and then outputting the direct-current power switched by the switching element, a square wave generating section for generating a square wave with a constant duty cycle to control switching by the switching element, and a control section for watching an output voltage of the smoothing section to control a period of generating the square wave generated by the square wave generating section so that the output voltage may be organized within a certain range.

The invention relates to a double-stranded compound, preferably an oligoribonucleotide, which down-regulates the expression of a human p53 gene. The invention also relates to a pharmaceutical composition comprising the compound, or a vector capable of expressing the oligoribonucleotide compound, and a pharmaceutically acceptable carrier. The present invention also contemplates a method of treating a patient suffering from alopecia or acute renal failure or other diseases comprising administering to the patient the pharmaceutical composition in a therapeutically effective dose so as to thereby treat the patient. The alopecia may be induced by chemotherapy or radiotherapy, and the patient may be suffering from cancer, in particular breast cancer.

Improved methods of treating water and hydrocarbons producing subterranean formations to reduce the water permeabilities of the formations without substantially reducing the hydrocarbons permeabilities thereof are provided. The methods basically comprise introducing into the formation a chemical which does not resist water flow and attaches to adsorption sites on surfaces within the porosity of the formation but slowly washes off the sites as another fluid flows through the treated formation. Thereafter, a water flow resisting polymer is introduced into the formation so that it flows deeply into the porosity of the formation before the previously introduced chemical washes off and attaches to the adsorption sites as the chemical washes off.

Methods, systems, and devices are disclosed for providing selective and non-selective cooling and warming of a patient. Multiple embodiments of devices are disclosed for performing rapid induction and maintenance of therapeutic hypothermia either in a hospital setting or in the field so that hypothermic treatment can be quickly instituted before significant tissue damage occurs. Methods are also disclosed for targeting brain cooling by irrigating the upper airway, aerodigestive tract, and / or more generalized cooling by irrigating the esophagus and / or stomach.

The invention relates to a double-stranded compound, preferably an oligoribonucleotide, which down-regulates the expression of a human p53 gene. The invention also relates to a pharmaceutical composition comprising the compound, or a vector capable of expressing the oligoribonucleotide compound, and a pharmaceutically acceptable carrier. The present invention also contemplates a method of treating a patient suffering from alopecia or acute renal failure or other diseases comprising administering to the patient the pharmaceutical composition in a therapeutically effective dose so as to thereby treat the patient. The alopecia may be induced by chemotherapy or radiotherapy, and the patient may be suffering from cancer, in particular breast cancer.

The invention relates to a double-stranded compound, preferably an oligoribonucleotide, which down-regulates the expression of a human p53 gene. The invention also relates to a pharmaceutical composition comprising the compound, or a vector capable of expressing the oligoribonucleotide compound, and a pharmaceutically acceptable carrier. The present invention also contemplates a method of treating a patient suffering from alopecia or acute renal failure or other diseases comprising administering to the patient the pharmaceutical composition in a therapeutically effective dose so as to thereby treat the patient. The alopecia may be induced by chemotherapy or radiotherapy, and the patient may be suffering from cancer, in particular breast cancer.

Provided is a methodology and system for applying coatings onto the interior surfaces of components. The approach comprises a vapor creation device (for example an electron beam or laser that evaporates a single or multiplicity of solid or liquid sources), a vacuum chamber having a moderate gas pressure (between about 10−4 to about 103 Torr) and a inert gas jet having controlled velocity and flow fields of gas jet. The gas jet is created by a rarefied, inert gas supersonic expansion through a nozzle. By controlling the carrier gas flow into a region upstream of the nozzle an upstream pressure is achieved (i.e. the gas pressure prior to its entrance into the processing chamber through the nozzle). The carrier gas flow and chamber pumping rate control the downstream (or chamber) pressure (i.e., downstream of the nozzle). The ratio of the upstream to downstream pressure along with the size and shape of the nozzle opening controls the speed of the gas entering the chamber. The carrier gas molecular weight (compared to that of the vapor) and the carrier gas speed controls its effectiveness in redirecting the vapor atoms via binary collisions towards the substrate. The speed and flux of the atoms entering the chamber, the nozzle parameters, and the operating chamber pressure can all vary leading to a wide range of accessible processing conditions. Vapor created from a source is transported into the interior regions of a component using binary collisions between the vapor and gas jet atoms. Under certain process conditions these collisions enable the vapor atoms to scatter onto the interior surfaces of the component and deposit.

A vehicle turn signaling apparatus includes a light source that is powered by a turn signal circuit of the vehicle. The light source is configured to project a low divergence visible line onto a driving lane adjacent to the vehicle in response to activation of the turn signal circuit to visibly warn other drivers where a driver of the vehicle may intend to move the vehicle.

Method for measuring weekly and annual emissions of a greenhouse gas generated over a determined geographical area and measuring system implementing the method.

An approach for the treatment of surfaces in public places with ultraviolet light is disclosed. In one embodiment, a disinfection illuminator having ultraviolet radiation sources can irradiate a number of contact surfaces. A control unit can control the ultraviolet irradiation of the contact surfaces. The disinfection illuminator is suitable for a wide variety of devices that are used by the general public. Gas station pumps, door knobs, key pads, and bathrooms are illustrative of examples of some devices and places having commonly-used surfaces that can be treated by the disinfection illuminator.

The invention relates to a filter element consisting of a molded body of porous concrete, which element is arranged in the water stream of a purification system. In particular, the filter element (10) is a molded pervious concrete layer arranged as a partition between a lower compartment (9) and an upper compartment (11) of a treatment chamber (8), wherein the water inlet (12) opens into the lower compartment (9) and a water outlet (17) issues from the upper compartment (11). The pervious concrete filter layer may contain one or more additives to enhance adsorption of pollutants, such as heavy metal ions, phosphorous, hydrocarbons or other target soluble pollutants.

An ultraviolet flux multiplying air sterilization chamber comprises inner surfaces having a diffuse reflective behavior. The sterilization chamber includes an inlet aperture and an outlet aperture for air to flow through said chamber and a light source emitting an ultraviolet light. Due to the reflectivity of the inner surfaces of the chamber, a flux of the ultraviolet light is multiplied by reflecting multiple times from the inner surfaces of the chamber. The inlet and outlet apertures are advantageously configured to reduce the amount of light that escapes from the chamber and increase the amount of photons available in the chamber. In an exemplary embodiment, perforated end panels having diffuse, reflective interior surfaces may be provided over at least a portion of the inlet and outlet apertures.

A fabric and method to support garments comprising opaque heat-moldable circular knit fabrics having relatively high amounts of spandex material as well as sufficient amounts of other fibers to simultaneously provide maximum support and maximum comfort to a wearer and which can be easily molded to the specifications of a wearer's body dimensions. Such high-spandex content, moldable garment fabrics are novel to the industry since the permissible added amount of spandex within such fabrics has been limited due to the power, modulus strength, and elongation of such fibers. Furthermore, the ability to provide moldable, high-spandex circular knit fabrics has been limited, if not impossible, due to the above-noted characteristics of the spandex fibers themselves. The inventive moldable fabrics and garments provide such desirable spandex properties while also increasing the comfortability to the wearer. The method of producing such fabrics is also contemplated within this invention. Both the fabric and the method state that the amount of spandex in the fabric is at least 24% of the total fiber weight in the fabric.

A method for treating an inflammation in skin of a patient includes irradiating the skin with infrared (IR) radiation in a first wavelength band and with violet / blue light in a second wavelength band.

A traffic signal control method comprises confirming the shortest green light interval; confirming the conflict area of the different traffic flow and the key conflict point position according to the engineering design for road canalization; confirming the longest clear distance si(m) of the traffic tail unit of green light i and the shortest entry distance sj(m) of the traffic head unit of green light j in conflict with green light i; calculating the longest clear time Max{ti} of the traffic tail unit of green light i and the shortest entry time Min{tj} of the traffic head unit of green light j; calculating the shortest green light interval Iij=A+Max{ti}−Min{tj}; confirming the control scheme for the crossing according to the shortest green light interval and sending the control instruction to the traffic signal display device for displaying in real time according to the control scheme. A traffic signal control system and special equipment are also provided.

An in situ soil remediation system may be used to remove or reduce levels of mercury contamination within soil. The soil remediation system may also remove or reduce levels of other contaminants within the soil. Mercury may be vaporized within the soil by a heating system. The vaporized mercury may be removed from the soil by a vacuum system. The vaporized mercury may pass through heated risers that elevate the vaporized mercury. After the vaporized mercury passes from the heated risers, the vaporized mercury may be allowed to cool, condense, and flow downward to a treatment facility. Removing mercury from the soil as a vapor may provide an economical, safe, and efficient way to remediate mercury contaminated soil.

This invention relates to a method of reducing cardiovascular morbidity and mortality in a prediabetic or Type 2 Diabetes patient population. The method comprises administering an effective dosage of a long acting insulin, preferably insulin glargine, to a prediabetic or Type 2 Diabetes patient.

A knee bolster, disposed within the instrument panel of an automotive vehicle, for absorbing energy from impact with the knees of an occupant of the automotive vehicle, the knee bolster assembly comprising a skin defining a show surface of the instrument panel, an inner panel secured to the skin, the inner panel including at least one male portion protruding therefrom in a direction away from the skin, at least one energy absorbing structure extending in a direction away from the inner panel, the energy absorbing structure having portions defining at least one recess therein, the male portions of the inner panel being received within the recess of the energy absorbing structures in a non-contacting alignment.

A user interface, telephony device, and method for managing user control settings associated with a telephony device is described. The user interface displays a label array on a display device of the telephony device. The label array includes at least one row of labels, each representing a discrete function or feature associated with the telephony device. A button array is provided in the vicinity of the display device. The button array includes a corresponding row or rows of buttons, each button representing a discrete function or feature for the telephony device and corresponding to a label within the label array. One or more buttons in the button array are selectively illuminated to indicate a status of one or more functions or features associated with one or more labels in the label array.

A data-entry device having manually operable input means arranged in zones for operation by corresponding fingers of a user. The device includes means for color coding such that each zone is assigned a color and successive zones display colors ordered according to their relative positions within a spectrum-ordered color pattern. In one embodiment the device includes a keyboard, such as for a computer or typewriter, wherein the keys of the keyboard are color-coded according to a spectrum-ordered color pattern. The invention also provides a method of color coding a data-entry device.

A user interface, telephony device, and method for managing user control settings associated with a telephony device is described. The user interface displays a label array on a display device of the telephony device. The label array includes at least one row of labels, each representing a discrete function or feature associated with the telephony device. A button array is provided in the vicinity of the display device. The button array includes a corresponding row or rows of buttons, each button representing a discrete function or feature for the telephony device and corresponding to a label within the label array. One or more buttons in the button array are selectively illuminated to indicate a status of one or more functions or features associated with one or more labels in the label array.

The subject of the invention is an anode block (13, 13a-13e) made of carbon for a pre-baked anode (4) for use in a metal electrolysis cell (1) comprising a higher face (24), a lower face (23), designed to be laid out opposite a higher face of a cathode (9), and four side faces (21,22,34), and including at least one first groove (31a-31e) leading onto at least one of the side faces, in which the first groove has a maximum length Lmax in a plane parallel to the lower face, and characterized in that the first groove does not lead onto said lower or higher faces, or leads onto said lower or higher faces over a length L0 less than half the maximum length Lmax.

An open mesh insect control material is described which includes an insect contact surface, an internal surface, apertures communicating both surfaces and a plurality of filamentous projections protruding from the insect contact surface the projections at least partly occlude the apertures. The structure is suitable for use in pest control especially as a mosquito net.

A method of fracking carbonate-rich reservoirs, comprising injecting a cryogenic or chilled fluid followed by an acid into said reservoir, allowing the acid to etch said reservoir, and thereby increasing production of a fluid, such as water, oil or gas, from said reservoir.

A vehicle turn signaling apparatus includes a light source that is powered by a turn signal circuit of the vehicle. The light source is configured to project a low divergence visible line onto a driving lane adjacent to the vehicle in response to activation of the turn signal circuit to visibly warn other drivers where a driver of the vehicle may intend to move the vehicle.

A novel photoimageable system for a two-chemistry system containing liquid photoreactive asymmetric acrylate compound containing sulfur, aromatic moieties, and optionally bromine, and an aluminum salt compound is disclosed. The photoimageable system has high dynamic range (M / #) and sensitivity and unexpectedly high temperature and high humidity resistance. The photoimageable system retains its dynamic range when exposed to 60° C. for 4 weeks while a composition without the aluminum salt compound lost 75% of its dynamic range under similar exposure conditions. In one embodiment, 2-10 weight % of a thio-butylacrylate dissolved in a two-component urethane matrix containing 0.002 to 1 weight % of the aluminum salt compound showed a dynamic range of greater than 5 for a 200 microns thick sample and retained more than 80% of the dynamic range after 4 weeks exposure at 60° C.