153 results about "Hydroxyquinolines" patented technology

To provide a pharmaceutical composition comprising a novel compound which has a thyroid-stimulating hormone receptor antagonist activity and is useful for the treatment of thyroid-related diseases.SOLUTION: There is provided a pharmaceutical composition comprising a 3,4-dihydroquinolin-2(1H)-one compound represented by a formula (I) or a pharmacologically acceptable salt thereof. A pharmaceutical composition comprising the compound or the pharmacologically acceptable salt thereof has an antagonist activity against thyroid-stimulating hormone receptors and is useful as a therapeutic agent or the like for thyroid-related diseases (for example, hyperthyroidism, Graves' disease, thyroid eye disease and thyroid cancer).SELECTED DRAWING: None

The invention relates to a fluorescent probe for detecting negative electrode lithium precipitation in a lithium ion battery and a detection method, and belongs to the technical field of lithium ion batteries. The fluorescent probe comprises a complex formed by coordination combination of 8-hydroxyquinoline-5-sulfonic acid and metal ions, the complex emits fluorescence under excitation of ultraviolet light, and the standard electrode potential of a metal simple substance corresponding to the metal ions is higher than that of lithium. The fluorescent probe can rapidly, simply and sensitively realize qualitative and quantitative detection of negative electrode lithium precipitation, and compared with large-scale instruments and visual inspection, the fluorescent probe can effectively simplify operation, reduce cost and improve detection efficiency and accuracy, meanwhile, a battery does not need to be disassembled under the condition of full charge, and detection safety is improved.

The application relates to the technical field of silver powder preparation, and discloses a method for producing silver powder by using photovoltaic panel battery pieces, which comprises the following steps: S1, after waste photovoltaic battery pieces and acid liquor are initially mixed, a leaching agent is added for secondary mixing, and filtration is carried out to obtain a silver-containing liquid; S2, sodium chloride is added into the silver-containing liquid to obtain a precipitate; and S3, the precipitate is subjected to reduction treatment to obtain silver powder; and the components of the leaching agent include 8-hydroxyquinoline and / or pyridine-2,6-dicarboxylic acid. Through the technical scheme, the problem of low silver powder yield in the production of silver powder by using photovoltaic battery pieces in the related art is solved.

The invention discloses a mercury ion detection fluorescent probe based on quinoline as well as a preparation method and application of the mercury ion detection fluorescent probe. The fluorescent probe and a structural formula of the fluorescent probe are shown as a formula I in the specification. A quinoline derivative, namely 2-methyl-7-hydroxyquinoline, is used as a fluorescent chromophore, a thioester group is used as a recognition group, and the prepared fluorescent probe shows high sensitivity and high selectivity on Hg < 2 + > in a solution. The preparation method of the fluorescent probe is simple in steps, raw materials are easy to obtain, and the obtained product is a white flocculent solid, is easy to store, has a wide application prospect and can be produced and applied on a large scale.

The invention relates to the technical field of separation and purification devices, in particular to a separation and purification device for 8-hydroxyquinoline crystallization. The device comprises a crystallization kettle used for cooling an 8-hydroxyquinoline solution, a stirring assembly is arranged in the crystallization kettle, the stirring assembly is provided with a plurality of cleaning assemblies in the radial direction of the crystallization kettle, each cleaning assembly comprises a scraping part and a pneumatic part, the scraping parts are slidably connected to the side, close to the inner wall of the crystallization kettle, of the stirring assembly, and the pneumatic parts are arranged on the scraping parts. The pneumatic part is used for pushing the scraping part to be close to the inner wall of the crystallization kettle; the increased air pressure in the pressure-bearing cavity pushes the pressure-bearing plate to slide towards one side close to the contraction groove, the telescopic arm is pushed out of the contraction groove through the sliding rod, and due to the fact that large air pressure is accumulated in the pressure-bearing cavity before the telescopic arm stretches out of the contraction groove, the conical part is inserted into the crystal above the liquid level at the moment that the top of the contraction groove is completely out of shielding of the installation groove. The telescopic arm instantly releases large force, and it can be ensured that the conical part is inserted into crystals tightly combined with the inner wall of the crystallization kettle.

The present application relates to a kind of macromolecular heavy metal complexing agent containing 8-hydroxyquinoline and amido phosphate structure and its preparation method, the present application also relates to a kind of heavy metal antidote, and the use of the macromolecular heavy metal complexing agent of the present application in preparing drug for treating heavy metal poisoning.The macromolecular complexing agent of the present application has excellent binding capacity with cadmium, lead, mercury and other heavy metal ions, and is high in safety, has excellent and long-acting heavy metal protection effect.The preparation method of the present application can mass, simply and efficiently prepare the macromolecular complexing agent of the present application, and preparation process is simple, high in yield, raw material is cheap and easy to obtain, reaction condition is mild.

The application discloses a misaligned ten-membered cucurbituril-based assembly and application thereof in detecting and removing trinitrophenol. The assembly is assembled by using misaligned ten-membered cucurbituril and 8-hydroxyquinoline as raw materials. The misaligned ten-membered cucurbituril-based assembly is a novel supramolecular assembly, can be used for fluorescent identification of trinitrophenol in an aqueous solution, and has the characteristics of simple detection instrument, high selectivity, good sensitivity, wide detection range, fast response time, and the like. In addition, the misaligned ten-membered cucurbituril-based assembly has the characteristic of being capable of removing trinitrophenol in the aqueous solution.

The application discloses an 8-hydroxyquinoline anticancer zinc (II) complex and a synthesis method and application thereof. The 8-hydroxyquinoline anticancer zinc (II) complex is synthesized by taking 5,7-diiodo-8-hydroxyquinoline, 5,7-dichloro-8-hydroxyquinoline, 5-chloro-7-iodo-8-hydroxyquinoline, 5,7-dibromo-8-hydroxyquinoline and 5-chloro-8-hydroxyquinoline as a first ligand and taking 4,4'-dimethoxy-2,2'-bipyridine, 4,4-di-tert-butyl-2,2-bipyridine, 5,5'-dimethyl-2,2-bipyridine, 2,2-bipyridine and 4,4'-dimethyl-2,2'-bipyridine as auxiliary ligands. The 8-hydroxyquinoline anticancer zinc (II) complex has good inhibiting effect on SK-OV-3CR cells of an ovarian cancer drug-resistant strain, is higher than that of cisplatin drugs, overcomes drug resistance of clinical drugs, has potential medicinal value and can be used for preparation of various antitumor drugs.

The application discloses a PO4 3‑ and a preparation method of a flame-retardant epoxy acrylate coating layer of 8-OQ intercalated zinc-aluminum hydrotalcite, and the coating layer. Phosphate ions are intercalated between layers by using the ion-exchangeability between layers, and other intercalation agents are used to increase the intercalation rate of phosphate ions before the phosphate ions are embedded into the layers. 8-hydroxyquinoline as an intercalation agent can effectively expand the interlayer spacing of hydrotalcite, and provide more space for anion exchange. The Zn / Al-PO4 3‑ -LDHs intercalated with 8-hydroxyquinoline has the optimal flame-retardant and mechanical properties of the coating layer of the EA compound system. The hydrotalcite can make the carbon layer more uniform, more dense and more solid, and increase the carbon content of the coating layer, so as to improve the flame retardancy and thermal stability of the composite coating, and provide a new method for the research on the hydrotalcite modified EA fireproof coating.

This invention provides a method for preparing a foamed copper-based composite organic compound layer catalytic material, comprising the following steps: forming 8-hydroxyquinoline molybdenum (Mo(C)) on the surface of a foamed copper matrix. 9 H 6 NO) 4 Organic compound layer; 8-hydroxyquinoline molybdenum (Mo(C)) 9 H 6 NO) 4 The organic compound layer is converted into phthalimide 8-hydroxyquinoline molybdenum (C). 8 H 4 NO 2 ) 2 (C 9 H 6 NO) 2 ; Phthalimide 8-hydroxyquinoline molybdenum Mo(C) 8 H 4 NO 2 ) 2 (C 9 H 6 NO) 2 Conversion to copper phthalimide / 8-hydroxyquinoline molybdenum Cu(C) 8 H 4 NO 2 ) 2 / Mo(C 9 H 6 NO) 2 The foamed copper-based composite organic compound layer catalytic material is finally obtained. The catalytic material prepared by the method of this invention can effectively improve the Faradaic efficiency, ammonia selectivity, production rate, and nitrate removal rate of the electrochemical reduction of nitrate to ammonia technology.

The invention relates to the technical field of cut flower postharvest preservation, and discloses a preservation pre-treatment solution for maintaining moisture-nutrition-microecological balance in a storage period of babysbreath cut flowers and a synergistic application method thereof. The pre-treatment liquid is prepared from the following components in percentage by weight / volume: 15 to 30 g / L of cane sugar, 15 to 30 g / L of trehalose, 100 to 200 mg / L of 8-hydroxyquinoline citrate, 50 to 150 mg / L of citric acid, 50 to 100 mg / L of carboxymethyl chitosan, 0.3 to 1.0 g / L of lysozyme-chitosan compound, 5 to 15 mg / L of nano silver-loaded silicon dioxide, 0.1 to 1.0 g / L of manganese citrate and 0.5 to 1.0 g / L of calcium nitrate. And 5 to 10 mL / L of glycerol and 0.5 to 5.0 mL / L of Tween-20 in percentage by volume. Through component collaborative design-process precise control-package matching innovation, the bottleneck of double loss of water and nutrition in the storage period is broken through, the pain points of no flowering and gray mold outbreak after storage are solved, a whole-process nursing scheme is provided for long-distance and short-distance transportation and storage of the babysbreath cut flowers, the commodity rate of the cut flowers is remarkably increased, and the economic benefit is increased. The method is suitable for flower harvesting bases, cold chain transportation and wholesale markets, and is especially suitable for air transportation exits.

The invention relates to the related technical field of organic synthesis, in particular to a preparation method of an aldehyde compound, an ortho-diketone compound and a hydroxyquinolinone derivative, which comprises the following steps: firstly, mixing a benzoyl methyl substituted triazole compound, water and a Fecatalyst in an oxygen atmosphere, and reacting under a heating condition; and then carrying out post-treatment on the reaction system to obtain the aldehyde compound, the o-diketone compound or the hydroxyquinolinone derivative. By introducing the Fecatalyst, the oxidation process of benzoylmethyl substituted triazole can be effectively catalyzed, so that the functionalization of triazole molecules is realized. The synthesis method is mild in reaction condition, simple and convenient to operate, high in product yield and low in cost, and has a good application prospect and popularization value.

The invention relates to a lithium extraction method based on extraction-back extraction, which comprises the following steps: carrying out extraction and phase separation on a lithium-containing solution by using a composite extraction liquid to obtain a lithium-containing loaded oil phase, the composite extraction liquid comprises an extraction agent and a diluent, and the diluent is selected from 1, 2, 3-trimethyl-1, 3-pentanediol monoisobutyrate or 1, 2, 3-trimethyl-1, 3-pentanediol monoisobutyrate. The crown ether is at least one of 2, 3-dipropoxy crown ether, 15-crown ether-5, dibenzo-18-crown ether-6, calix [4] arene, calix [6] arene, calix [8] arene, tricyclodecenyl acetate, benzothiazole and 7-(4-ethyl-1-methyl octyl)-8-hydroxyquinoline; cO2 is introduced into the lithium-containing loaded oil phase to be mixed, a gas-liquid mixture is obtained, then the gas-liquid mixture is mixed with water to be subjected to reverse extraction and phase separation, and reverse extraction liquid is obtained; and carrying out heat treatment on the strip liquor to obtain lithium carbonate. According to the invention, CO2 is firstly introduced into the lithium-containing loaded oil phase for mixing, so that CO2 gas molecules can be effectively dispersed and adsorbed in pore channels, the utilization rate of CO2 is improved, the energy consumption can be effectively reduced, and the production efficiency is improved.

The present invention discloses an organic heterojunction nanowire array, a preparation method thereof, and an optoelectronic device. The preparation method includes: preparing a nanoscale channel array on the surface of a substrate, and then performing a hydrophobic treatment on the surface; by means of a first mask plate having a first through-hole array, preparing a metal phthalocyanine nanowire array on the surface by physical vapor deposition; and then by means of a second mask plate having a second through-hole array, preparing an aluminum tris(8-hydroxyquinoline) nanowire array on the surface by physical vapor deposition, wherein the second through-hole array is used to control the growth region of the aluminum tris(8-hydroxyquinoline) nanowire array, so that the aluminum tris(8-hydroxyquinoline) nanowire array overlaps with the metal phthalocyanine nanowire array, and an organic heterojunction nanowire array is prepared. This preparation method can achieve the directional growth and alignment of organic heterojunction nanowires, and further can achieve the in-situ large-scale construction and integration of nanowire device arrays.

The application discloses a high-activity 8-hydroxyquinoline rhodium complex in vivo and in vitro and a synthesis method and application thereof. The 5,7-dichloro-8-hydroxy-2-methylquinoline, dichloro (pentamethylcyclopentadienyl) rhodium (III) dimer, methanol, dimethyl sulfoxide and triethylamine are taken, and under a closed condition, the reaction is carried out at 80 DEG C for 3 days; after being cooled to 37 DEG C, filtration and drying are carried out, and the 5-chloro-8-hydroxyquinoline rhodium complex is obtained. The 5-chloro-8-hydroxyquinoline rhodium complex has obvious inhibiting effect on SK-OV-3 and SK-OV-3 / DDP cancer cells, shows superior antitumor activity, and has small toxicity to normal HL-7702 cells; the 5-chloro-8-hydroxyquinoline rhodium complex has potential medicinal value and is expected to be used for preparation of various antitumor drugs.

This invention discloses an Fe-doped graphitic carbon nitride material with nitrogen defects, its preparation method, and application. Iron nitrate nonahydrate and 8-hydroxyquinoline are heated in a water bath, and after adjusting the pH, an inky iron ligand is precipitated. The iron ligand is then mixed with melamine and calcined in air to obtain a gray-black powder material, CN-Q-Fe. This material has great potential for treating antibiotic contamination in aquatic environments, and exhibits excellent photocatalytic degradation of tetracycline antibiotics.

The application relates to the technical field of adhesion agents, and discloses a preparation method of an environment-friendly adhesion agent for aluminum alloy, which comprises the following steps: adding water, potassium hydroxide, sodium chloride, sodium gluconate, anhydrous tripotassium phosphate, polyether DF-20, 8-hydroxyquinolyl polycarboxylic acid adhesion agent, sulfosuccinate and sodium isooctyl alcohol sulfate into a reaction kettle and stirring uniformly to obtain the environment-friendly adhesion agent for aluminum alloy. The 8-hydroxyquinolyl group contained in the 8-hydroxyquinolyl polycarboxylic acid adhesion agent can interact with the surface of the aluminum alloy or the tinplate through coordination, and meanwhile, the carboxyl contained in the polycarboxylic acid adhesion agent can interact with the carboxyl and other groups in the water-based acrylic resin emulsion through hydrogen bonding, so that the polycarboxylic acid adhesion agent plays a bridging role between the aluminum alloy and the acrylic resin paint film, the adhesion and the bonding performance between the acrylic resin paint film and the base material are enhanced, and better adhesion grade and greater T-peeling strength are achieved.

The application discloses a preparation method and application of a bimodal linear polyethylene chromium carbene catalyst, and belongs to the technical field of chemical synthesis. The preparation method comprises the following steps: 1-nitro-2-aromatic sulfide benzene is prepared by taking 1-fluoro-2-nitrobenzene, aromatic mercaptan and potassium tert-butanolate as raw materials; 1-amino-2-aromatic sulfide benzene is prepared by taking 1-nitro-2-aromatic sulfide benzene and hydrazine hydrate as raw materials; 8-hydroxyimidazol[1,5-alpha] quinolinium salt is prepared by taking 1-amino-2-aromatic sulfide benzene, 8-hydroxyquinoline-2-methyl formaldehyde, formaldehyde solution and hydrogen chloride-1,4-dioxane solution as raw materials; and finally, the reaction is carried out by taking 8-hydroxyimidazol[1,5-alpha] quinolinium salt, silver trifluoromethanesulfonate, sodium bis(trimethylsilyl) amide and chromium trichloride as raw materials to obtain the bimodal linear polyethylene chromium carbene catalyst. According to the preparation method, the catalyst is effectively prevented from being poisoned, the catalytic activity of the catalyst is improved, and the catalyst has good thermal stability.

The invention discloses an efficient synthesis method of brexpiprazole, which comprises the following steps: taking 4-bromo-benzothiophene and N-Boc-piperazine as initial raw materials, under the protection of nitrogen, carrying out reaction by using a supported catalyst to prepare 4-Boc piperazine benzothiophene, and then carrying out acidolysis to obtain 4-piperazine benzothiophene hydrochloride; the method comprises the following steps: reacting 3, 4-dihydro-7-hydroxy-2 (1H) quinolinone with 1-bromo-4-chloro-butane to generate 3, 4-dihydro-7-(4-chlorobutoxy)-2 (1H)-quinolinone, and then converting the 3, 4-dihydro-7-(4-chlorobutoxy)-2 (1H)-quinolinone into 7-(4-chlorobutoxy)-2 (1H)-quinolinone; then condensing with 4-piperazine benzothiophene hydrochloride to obtain a crude product of brexpiprazole; and finally, crystallizing and purifying for multiple times to obtain high-purity brexpiprazole. According to the preparation method disclosed by the invention, 4-bromo-benzothiophene and N-Boc-piperazine are taken as starting raw materials, and high-purity brexpiprazole is prepared by optimizing selection of a catalyst and conditions of each step and through an excellent purification process.

This invention belongs to the field of MOF mixed matrix membrane technology, and discloses a MOF mixed matrix membrane for ion sieving and its preparation method. The preparation method includes dissolving an organic ligand and a metal source in an organic compound, ultrasonically treating it to obtain a precursor solution, subjecting the precursor solution to a hydrothermal reaction to obtain a first intermediate product, washing and vacuum drying the first intermediate product to obtain MOF-808 powder; dissolving 8-hydroxyquinoline in anhydrous ethanol, adding the MOF-808 powder, and sealing and stirring to obtain 8-Hq@MOF-808 powder; filtering the 8-Hq@MOF-808 powder onto a substrate, spin-coating an epoxy resin solution onto the substrate containing the 8-Hq@MOF-808 powder, and drying at room temperature to obtain the MOF mixed matrix membrane. The phenolic hydroxyl oxygen atom and pyridine ring nitrogen atom of 8-hydroxyquinoline act as bidentate ligands, forming a stable five-membered chelate ring with metal ions, exhibiting high coordination efficiency.

The present invention discloses a method for preparing a copper sheet corrosion inhibitor for gasoline and diesel components produced as byproducts from the hydrogenation of waste lubricating oils, belonging to the technical field of petroleum product corrosion inhibition. The method comprises preparing a saturated isooctane / n-hexadecane solution of tetrazole; preparing an n-octane / n-hexadecane solution of 8-hydroxyquinoline or imidazole; mixing dropwise, adjusting the pH, and heating in a water bath; adding organic cerium, cooling, and aging the solution. The copper sheet corrosion inhibitor for gasoline and diesel components produced as byproducts from the hydrogenation of waste lubricating oils prepared using this method can significantly reduce the corrosion level of the copper sheet produced as a byproduct from the hydrogenation of waste lubricating oils, even at a very low dosage, thereby achieving the technical purpose of inhibiting copper sheet corrosion.

The invention belongs to the field of material science and court science, and discloses a luminescent ZIF-8 material and a preparation method and application thereof. The invention relates to a novel luminescent ZIF-8 material, which is a luminescent material prepared by taking ZIF-8 and 8-hydroxyquinoline as raw materials, taking NaCl as a dispersion medium and modifying 8-HQ on the surface of the ZIF-8 through a solid-phase grinding method. The invention also discloses application of the luminescent ZIF-8 material in preparation of a latent fingerprint development agent or application in latent fingerprint development. The FZIF-8 can be used for latent fingerprint display, primary and secondary structure information can be clearly observed through naked eyes without other observation tools, and distribution of sweat pores in a tertiary structure can even be observed after a local image is further amplified through a microscope. The FZIF-8 shows good sensitivity and selectivity in the detection of the LFPs, and has relatively low background interference.

The application discloses an aluminum profile spraying powder coating and a preparation method thereof, and belongs to the technical field of paint. The application introduces modified resin, so that the coating has excellent weather resistance, and adds specific proportion of proto-catechuic acid, 2-(4-thiazolyl) benzimidazole and 8-hydroxyquinoline as an antibacterial agent, and chemically bonds the antibacterial agent to the resin base material, so that efficient, long-lasting and broad-spectrum antibacterial effect is realized, and more significant antibacterial purpose is realized, and the problems of easy migration and easy failure of the surface spraying antibacterial agent are effectively solved. The application optimizes the overall formula, and the components interact with each other, so that the coating has excellent surface flatness and apparent quality, and the defects of pinholes and orange peel commonly existing in traditional coatings are avoided; the overall antibacterial and long-lasting antibacterial properties are significant, and the application is particularly suitable for buildings, medical treatment and household aluminum profiles with high sanitary requirements.

The invention relates to a clioquinol for use in the prevention or treatment of psoriasis or of inflammatory bowel disease (IBD).

The invention discloses an application of 5-nitro-8-hydroxyquinoline in activation of a TMEM175 channel and a preparation method of the 5-nitro-8-hydroxyquinoline. The invention further discloses a method for activating the TMEM175 channel. The method comprises the step of using the 5-nitro-8-hydroxyquinoline, the pharmaceutically acceptable salt of the 5-nitro-8-hydroxyquinoline and / or the isotope derivative of the 5-nitro-8-hydroxyquinoline. According to the invention, the small molecule 5-nitro-8-hydroxyquinoline which specifically targets the TMEM175 channel and can activate the TMEM175 channel is screened, and the result proves that the 5-nitro-8-hydroxyquinoline can be used as a compound targeting the TMEM175 channel and is used for preparing medicines for treating neurodegenerative diseases, such as Parkinson's disease and / or Lewy body dementia.

The invention discloses a rubber adhesive for improving wear resistance by using wet-skid-resistant epoxy resin and a preparation process of the rubber adhesive, and relates to the field of rubber adhesives. Comprising the following raw materials in parts by weight: 60-70 parts of solution polymerized styrene-butadiene rubber, 85-95 parts of modified epoxy resin, 20-25 parts of carboxy nitrile rubber, 10-15 parts of filler, 2-3 parts of a coupling agent, 3-5 parts of a vulcanizing agent, 8-10 parts of a curing agent, 6-8 parts of a plasticizer, 1-3 parts of an anti-aging agent and 35-40 parts of a solvent. The modified epoxy resin is obtained by reacting a bisphenol product, namely a product 6, with epoxy chloropropane, wherein the bisphenol product is prepared by taking 8-hydroxyquinoline-4-carboxylic acid methyl ester, tetradecylamine, 1-(2-chloroethoxy)-2-(2-methoxyethoxy) ethane, 3-nitro-9H-fluorene-9-ketone and phenol as main raw materials. The rubber adhesive disclosed by the invention has relatively strong impact resistance, wear resistance, water resistance and antibacterial property.

The application discloses a kind of 8-hydroxyquinoline-pyridine anticancer zinc (II) complex preparation and application, belong to medical technology field, solve the technical problem of drug resistance of prior art in cisplatin, the method is as follows: Zn (NO3) 2·6H2O, methanol and dichloromethane mixed solution and second ligand are mixed in pressure tube, and cover tightly cover, under 60-70 ℃ 3 days, after reaction, cooling to room temperature, first ligand and triethylamine are added to pressure tube, place in closed environment, under 75-85 ℃ 3 days, cooling to room temperature and stationary, obtain target complex. 50 It is found that the complex has good inhibitory effect on SK-OV-3 / DDP, the IC 50 value is 1.45-10.14 μM, and the toxicity to normal cells HL-7702 is very small, which shows that the complex has selectivity to tumor cells SK-OV-3 / DDP, overcomes the drug resistance of clinical drug, has potential medicinal value, and is expected to be used for the preparation of various antitumor drugs.

The application provides an aluminum ion detection reagent and a preparation method and application thereof, and aims to solve the problems of high cost, complex technology, time consumption and unallowable high-throughput analysis of aluminum ion detection in the prior art. 3+ The aluminum ion detection reagent contains the following structure: and the preparation method comprises the following steps: (1) adding 2-chlorobenzaldehyde and 2-chloroaniline into a first solvent, carrying out a heating reflux reaction, and then carrying out purification treatment to obtain an intermediate product; (2) adding alkali, 8-hydroxyquinoline and a second solvent into the intermediate product, carrying out a reaction at room temperature, and then carrying out purification treatment, and the aluminum ion detection reagent is obtained. ‑7 The aluminum ion detection reagent can qualitatively and quantitatively detect aluminum ions, and the detection limit reaches 2.24*10 MM.

The invention discloses a lead-doped titanium-oxygen cluster compound with medium and high nuclear numbers as well as a preparation method and application thereof, and belongs to the field of materials, fine chemical engineering and photocatalytic materials. The molecular formula of the lead-doped titanium oxygen cluster compound with the medium and high nuclear numbers is H3Ti16Pb6 (mu4-O) 4 (mu3-O) 12 (mu2-O) 10 (Bz) 18 (OQ) 8 (OAc), mu4-O represents a four-bridged O atom, mu3-O represents a three-bridged O atom, mu2-O represents a two-bridged O atom, Bz represents a benzoic acid ligand, OQ represents an 8-hydroxyquinoline ligand, and OAc represents an acetic acid ligand. The preparation method is simple, raw materials are easy to obtain, and industrial production is easy; and the post-treatment is simple, and the pollution is less. According to the lead-doped titanium-oxygen cluster compound with the medium and high nuclear numbers prepared by the method, due to coordination of the 8-hydroxyquinoline, the band gap width of the titanium-oxygen cluster compound is reduced, and the response capability to visible light is improved.

The invention provides an 8-hydroxyquinoline functionalized MOF (Metal Organic Framework) material as well as a preparation method and application thereof, and belongs to the field of scattered metal adsorption materials, the 8-hydroxyquinoline functionalized MOF material comprises a UiO-66-NH2 metal organic framework and an 8-hydroxyquinoline ligand grafted with an amino functional group in the UiO-66-NH2 metal organic framework. According to the invention, an 8-hydroxyquinoline ligand is introduced into a metal organic framework structure and is used as an adsorption site of gallium, so that the capability of capturing gallium is improved. The 8-hydroxyquinoline functionalized MOF material provided by the invention is obtained by cross-linking an 8-hydroxyquinoline ligand on a UiO-66-NH2 material through a cross-linking agent formaldehyde by adopting a hydrothermal synthesis method, and the synthesis method is simple. The 8-hydroxyquinoline functionalized MOF material (UiO-HQO) adsorption material provided by the invention can efficiently recover Ga in the vanadium titano-magnetite alkaline leaching solution, and the resource utilization rate is improved.