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173 results about "Hydroxyquinolines" patented technology

The 8-hydroxy derivatives inhibit various enzymes and their halogenated derivatives, though neurotoxic, are used as topical anti-infective agents, among other uses.

Oilfield water injection bactericide containing plant sterilization components and preparation method of oilfield water injection bactericide

The invention relates to the technical field of bactericides, and discloses an oilfield flooding bactericide containing plant bactericidal components and a preparation method thereof. The preparation method comprises the following steps: loading the plant-based traditional Chinese medicine extract and the isothiazolinone-based corrosion inhibitor on the silver-loaded cyclodextrin metal organic framework to prepare an antibacterial agent / silver-loaded cyclodextrin metal organic framework composite material, and mixing the antibacterial agent / silver-loaded cyclodextrin metal organic framework composite material with methyl methacrylate to prepare the antibacterial agent / silver-loaded cyclodextrin metal organic framework composite material. The bactericide obtained by carrying out copolymerization reaction on modified hydroxyquinoline, vinyl quaternary phosphonium salt and methacrylic acid through an in-situ polymerization method can effectively kill and inhibit the breeding of sulfate reducing bacteria and other bacteria in oilfield reinjection water, and has a certain corrosion inhibition effect.
Owner:ZHENGZHOU DERONG TECH CO LTD

Pharmaceutical composition comprising 3,4-dihydroquinolin-2(1H)-one compound

To provide a pharmaceutical composition comprising a novel compound which has a thyroid-stimulating hormone receptor antagonist activity and is useful for the treatment of thyroid-related diseases.SOLUTION: There is provided a pharmaceutical composition comprising a 3,4-dihydroquinolin-2(1H)-one compound represented by a formula (I) or a pharmacologically acceptable salt thereof. A pharmaceutical composition comprising the compound or the pharmacologically acceptable salt thereof has an antagonist activity against thyroid-stimulating hormone receptors and is useful as a therapeutic agent or the like for thyroid-related diseases (for example, hyperthyroidism, Graves' disease, thyroid eye disease and thyroid cancer).SELECTED DRAWING: None
Owner:KISSEI PHARMACEUTICAL CO LTD

Preparation method of 6063 aluminum alloy self-sealing micro-arc oxidation ceramic film layer

The invention relates to the technical field of corrosion-resistant coatings, and discloses a preparation method of a 6063 aluminum alloy self-sealing micro-arc oxidation ceramic film layer. Comprising the following operation steps that 1, 6063 aluminum alloy is sequentially subjected to oil removal, acid pickling, washing and drying, and prefabricated 6063 aluminum alloy is obtained; 2, the prefabricated 6063 aluminum alloy serves as an anode, a stainless steel container with a cooling system serves as a cathode, the prefabricated 6063 aluminum alloy and the stainless steel container are immersed in the electrolyte, a constant-current mode is adopted, micro-arc oxidation is conducted for 15-25 min, and a self-sealing micro-arc oxidation ceramic film layer test piece is obtained; 3, (1) carrying out hydrothermal treatment on the self-sealing micro-arc oxidation ceramic film layer test piece and carbonate precursor hydrotalcite at 115-120 DEG C for 20-24 hours to obtain a sample containing an LDH coating; and (2) putting a sample containing the LDH coating into the modified hydroxyquinoline solution, soaking at 40-50 DEG C for 3-4 hours, taking out and drying to obtain a product.
Owner:CHANGZHOU INST OF TECH

Fluorescent probe for detecting negative electrode lithium precipitation in lithium ion battery and detection method

The invention relates to a fluorescent probe for detecting negative electrode lithium precipitation in a lithium ion battery and a detection method, and belongs to the technical field of lithium ion batteries. The fluorescent probe comprises a complex formed by coordination combination of 8-hydroxyquinoline-5-sulfonic acid and metal ions, the complex emits fluorescence under excitation of ultraviolet light, and the standard electrode potential of a metal simple substance corresponding to the metal ions is higher than that of lithium. The fluorescent probe can rapidly, simply and sensitively realize qualitative and quantitative detection of negative electrode lithium precipitation, and compared with large-scale instruments and visual inspection, the fluorescent probe can effectively simplify operation, reduce cost and improve detection efficiency and accuracy, meanwhile, a battery does not need to be disassembled under the condition of full charge, and detection safety is improved.
Owner:ZHEJIANG ANGOTE ELECTRIC TECHNOLOGY CO LTD

A method for producing silver powder by using photovoltaic panel cell pieces

The application relates to the technical field of silver powder preparation, and discloses a method for producing silver powder by using photovoltaic panel battery pieces, which comprises the following steps: S1, after waste photovoltaic battery pieces and acid liquor are initially mixed, a leaching agent is added for secondary mixing, and filtration is carried out to obtain a silver-containing liquid; S2, sodium chloride is added into the silver-containing liquid to obtain a precipitate; and S3, the precipitate is subjected to reduction treatment to obtain silver powder; and the components of the leaching agent include 8-hydroxyquinoline and / or pyridine-2,6-dicarboxylic acid. Through the technical scheme, the problem of low silver powder yield in the production of silver powder by using photovoltaic battery pieces in the related art is solved.
Owner:XINGTAI SHENGBO METAL MATERIAL TECH CO LTD

Quinoline matrix-based mercury ion detection fluorescent probe as well as preparation method and application thereof

The invention discloses a mercury ion detection fluorescent probe based on quinoline as well as a preparation method and application of the mercury ion detection fluorescent probe. The fluorescent probe and a structural formula of the fluorescent probe are shown as a formula I in the specification. A quinoline derivative, namely 2-methyl-7-hydroxyquinoline, is used as a fluorescent chromophore, a thioester group is used as a recognition group, and the prepared fluorescent probe shows high sensitivity and high selectivity on Hg < 2 + > in a solution. The preparation method of the fluorescent probe is simple in steps, raw materials are easy to obtain, and the obtained product is a white flocculent solid, is easy to store, has a wide application prospect and can be produced and applied on a large scale.
Owner:JIANGSU UNIV OF SCI & TECH

Separation and purification device for 8-hydroxyquinoline crystallization

The invention relates to the technical field of separation and purification devices, in particular to a separation and purification device for 8-hydroxyquinoline crystallization. The device comprises a crystallization kettle used for cooling an 8-hydroxyquinoline solution, a stirring assembly is arranged in the crystallization kettle, the stirring assembly is provided with a plurality of cleaning assemblies in the radial direction of the crystallization kettle, each cleaning assembly comprises a scraping part and a pneumatic part, the scraping parts are slidably connected to the side, close to the inner wall of the crystallization kettle, of the stirring assembly, and the pneumatic parts are arranged on the scraping parts. The pneumatic part is used for pushing the scraping part to be close to the inner wall of the crystallization kettle; the increased air pressure in the pressure-bearing cavity pushes the pressure-bearing plate to slide towards one side close to the contraction groove, the telescopic arm is pushed out of the contraction groove through the sliding rod, and due to the fact that large air pressure is accumulated in the pressure-bearing cavity before the telescopic arm stretches out of the contraction groove, the conical part is inserted into the crystal above the liquid level at the moment that the top of the contraction groove is completely out of shielding of the installation groove. The telescopic arm instantly releases large force, and it can be ensured that the conical part is inserted into crystals tightly combined with the inner wall of the crystallization kettle.
Owner:HENAN UNIV OF URBAN CONSTR +1

A macromolecular heavy metal complexing agent containing 8-hydroxyquinoline and amido phosphate structure and a preparation method thereof

The present application relates to a kind of macromolecular heavy metal complexing agent containing 8-hydroxyquinoline and amido phosphate structure and its preparation method, the present application also relates to a kind of heavy metal antidote, and the use of the macromolecular heavy metal complexing agent of the present application in preparing drug for treating heavy metal poisoning.The macromolecular complexing agent of the present application has excellent binding capacity with cadmium, lead, mercury and other heavy metal ions, and is high in safety, has excellent and long-acting heavy metal protection effect.The preparation method of the present application can mass, simply and efficiently prepare the macromolecular complexing agent of the present application, and preparation process is simple, high in yield, raw material is cheap and easy to obtain, reaction condition is mild.
Owner:TSINGHUA UNIVERSITY

Modified rare earth algistat as well as preparation method and application thereof

The invention discloses a modified rare earth algistat as well as a preparation method and application thereof. The modified rare earth algistat is prepared by mixing a 2-hydroxypyridine nitrogen oxide rare earth derivative, 8-hydroxyquinoline lanthanum, cellulose powder and second soluble rare earth salt. The composite material can release rare earth ions in water. The ions interact with negative charges on the surface of the algae through electrostatic adsorption, so that a bridging effect is formed, and the algae are quickly gathered and finally precipitated, so that effective flocculation is realized; wherein the 8-hydroxyquinoline lanthanum and the 2-hydroxypyridine nitrogen oxide rare earth compound have remarkable antibacterial and algae-inhibiting effects.
Owner:XIAMEN INST OF RARE EARTH MATERIALS

Mispaired decameric cucurbituril-based assemblies and their application for detection and removal of trinitrophenol

The application discloses a misaligned ten-membered cucurbituril-based assembly and application thereof in detecting and removing trinitrophenol. The assembly is assembled by using misaligned ten-membered cucurbituril and 8-hydroxyquinoline as raw materials. The misaligned ten-membered cucurbituril-based assembly is a novel supramolecular assembly, can be used for fluorescent identification of trinitrophenol in an aqueous solution, and has the characteristics of simple detection instrument, high selectivity, good sensitivity, wide detection range, fast response time, and the like. In addition, the misaligned ten-membered cucurbituril-based assembly has the characteristic of being capable of removing trinitrophenol in the aqueous solution.
Owner:GUIZHOU UNIV

8-hydroxyquinoline-based anticancer zinc(ii) complexes, methods for their synthesis and use

The application discloses an 8-hydroxyquinoline anticancer zinc (II) complex and a synthesis method and application thereof. The 8-hydroxyquinoline anticancer zinc (II) complex is synthesized by taking 5,7-diiodo-8-hydroxyquinoline, 5,7-dichloro-8-hydroxyquinoline, 5-chloro-7-iodo-8-hydroxyquinoline, 5,7-dibromo-8-hydroxyquinoline and 5-chloro-8-hydroxyquinoline as a first ligand and taking 4,4'-dimethoxy-2,2'-bipyridine, 4,4-di-tert-butyl-2,2-bipyridine, 5,5'-dimethyl-2,2-bipyridine, 2,2-bipyridine and 4,4'-dimethyl-2,2'-bipyridine as auxiliary ligands. The 8-hydroxyquinoline anticancer zinc (II) complex has good inhibiting effect on SK-OV-3CR cells of an ovarian cancer drug-resistant strain, is higher than that of cisplatin drugs, overcomes drug resistance of clinical drugs, has potential medicinal value and can be used for preparation of various antitumor drugs.
Owner:YULIN NORMAL UNIVERSITY

PO4 3- and 8-OQ intercalated zinc-aluminum hydrotalcite, PO4 3- Preparation method of 8-OQ intercalated zinc-aluminum hydrotalcite flame-retardant epoxy acrylic coating and its coating

ActiveCN118956200BCarbon layerPhosphate ion
The application discloses a PO4 3‑ and a preparation method of a flame-retardant epoxy acrylate coating layer of 8-OQ intercalated zinc-aluminum hydrotalcite, and the coating layer. Phosphate ions are intercalated between layers by using the ion-exchangeability between layers, and other intercalation agents are used to increase the intercalation rate of phosphate ions before the phosphate ions are embedded into the layers. 8-hydroxyquinoline as an intercalation agent can effectively expand the interlayer spacing of hydrotalcite, and provide more space for anion exchange. The Zn / Al-PO4 3‑ -LDHs intercalated with 8-hydroxyquinoline has the optimal flame-retardant and mechanical properties of the coating layer of the EA compound system. The hydrotalcite can make the carbon layer more uniform, more dense and more solid, and increase the carbon content of the coating layer, so as to improve the flame retardancy and thermal stability of the composite coating, and provide a new method for the research on the hydrotalcite modified EA fireproof coating.
Owner:PUTIAN UNIV

Process for the preparation of a foamed copper-based composite organic compound layer catalytic material

This invention provides a method for preparing a foamed copper-based composite organic compound layer catalytic material, comprising the following steps: forming 8-hydroxyquinoline molybdenum (Mo(C)) on the surface of a foamed copper matrix. 9 H 6 NO) 4 Organic compound layer; 8-hydroxyquinoline molybdenum (Mo(C)) 9 H 6 NO) 4 The organic compound layer is converted into phthalimide 8-hydroxyquinoline molybdenum (C). 8 H 4 NO 2 ) 2 (C 9 H 6 NO) 2 ; Phthalimide 8-hydroxyquinoline molybdenum Mo(C) 8 H 4 NO 2 ) 2 (C 9 H 6 NO) 2 Conversion to copper phthalimide / 8-hydroxyquinoline molybdenum Cu(C) 8 H 4 NO 2 ) 2 / Mo(C 9 H 6 NO) 2 The foamed copper-based composite organic compound layer catalytic material is finally obtained. The catalytic material prepared by the method of this invention can effectively improve the Faradaic efficiency, ammonia selectivity, production rate, and nitrate removal rate of the electrochemical reduction of nitrate to ammonia technology.
Owner:NORTH CHINA UNIVERSITY OF TECHNOLOGY

Fresh-keeping pre-processing liquid for maintaining moisture-nutrition-microecological balance of babysbreath cut flowers in storage period and synergistic application method of fresh-keeping pre-processing liquid

The invention relates to the technical field of cut flower postharvest preservation, and discloses a preservation pre-treatment solution for maintaining moisture-nutrition-microecological balance in a storage period of babysbreath cut flowers and a synergistic application method thereof. The pre-treatment liquid is prepared from the following components in percentage by weight / volume: 15 to 30 g / L of cane sugar, 15 to 30 g / L of trehalose, 100 to 200 mg / L of 8-hydroxyquinoline citrate, 50 to 150 mg / L of citric acid, 50 to 100 mg / L of carboxymethyl chitosan, 0.3 to 1.0 g / L of lysozyme-chitosan compound, 5 to 15 mg / L of nano silver-loaded silicon dioxide, 0.1 to 1.0 g / L of manganese citrate and 0.5 to 1.0 g / L of calcium nitrate. And 5 to 10 mL / L of glycerol and 0.5 to 5.0 mL / L of Tween-20 in percentage by volume. Through component collaborative design-process precise control-package matching innovation, the bottleneck of double loss of water and nutrition in the storage period is broken through, the pain points of no flowering and gray mold outbreak after storage are solved, a whole-process nursing scheme is provided for long-distance and short-distance transportation and storage of the babysbreath cut flowers, the commodity rate of the cut flowers is remarkably increased, and the economic benefit is increased. The method is suitable for flower harvesting bases, cold chain transportation and wholesale markets, and is especially suitable for air transportation exits.
Owner:YUNNAN HUAYIMEI BIOTECHNOLOGY CO LTD

Preparation method of aldehyde compound, o-diketone compound and hydroxyquinolinone derivative

The invention relates to the related technical field of organic synthesis, in particular to a preparation method of an aldehyde compound, an ortho-diketone compound and a hydroxyquinolinone derivative, which comprises the following steps: firstly, mixing a benzoyl methyl substituted triazole compound, water and a Fecatalyst in an oxygen atmosphere, and reacting under a heating condition; and then carrying out post-treatment on the reaction system to obtain the aldehyde compound, the o-diketone compound or the hydroxyquinolinone derivative. By introducing the Fecatalyst, the oxidation process of benzoylmethyl substituted triazole can be effectively catalyzed, so that the functionalization of triazole molecules is realized. The synthesis method is mild in reaction condition, simple and convenient to operate, high in product yield and low in cost, and has a good application prospect and popularization value.
Owner:PINGDINGSHAN UNIVERSITY

Lithium extraction method based on extraction-back extraction

The invention relates to a lithium extraction method based on extraction-back extraction, which comprises the following steps: carrying out extraction and phase separation on a lithium-containing solution by using a composite extraction liquid to obtain a lithium-containing loaded oil phase, the composite extraction liquid comprises an extraction agent and a diluent, and the diluent is selected from 1, 2, 3-trimethyl-1, 3-pentanediol monoisobutyrate or 1, 2, 3-trimethyl-1, 3-pentanediol monoisobutyrate. The crown ether is at least one of 2, 3-dipropoxy crown ether, 15-crown ether-5, dibenzo-18-crown ether-6, calix [4] arene, calix [6] arene, calix [8] arene, tricyclodecenyl acetate, benzothiazole and 7-(4-ethyl-1-methyl octyl)-8-hydroxyquinoline; cO2 is introduced into the lithium-containing loaded oil phase to be mixed, a gas-liquid mixture is obtained, then the gas-liquid mixture is mixed with water to be subjected to reverse extraction and phase separation, and reverse extraction liquid is obtained; and carrying out heat treatment on the strip liquor to obtain lithium carbonate. According to the invention, CO2 is firstly introduced into the lithium-containing loaded oil phase for mixing, so that CO2 gas molecules can be effectively dispersed and adsorbed in pore channels, the utilization rate of CO2 is improved, the energy consumption can be effectively reduced, and the production efficiency is improved.
Owner:ZHEJIANG XINLIXIANG TECH CO LTD +1

An organic heterojunction nanowire array, a preparation method thereof, and an optoelectronic device

The present invention discloses an organic heterojunction nanowire array, a preparation method thereof, and an optoelectronic device. The preparation method includes: preparing a nanoscale channel array on the surface of a substrate, and then performing a hydrophobic treatment on the surface; by means of a first mask plate having a first through-hole array, preparing a metal phthalocyanine nanowire array on the surface by physical vapor deposition; and then by means of a second mask plate having a second through-hole array, preparing an aluminum tris(8-hydroxyquinoline) nanowire array on the surface by physical vapor deposition, wherein the second through-hole array is used to control the growth region of the aluminum tris(8-hydroxyquinoline) nanowire array, so that the aluminum tris(8-hydroxyquinoline) nanowire array overlaps with the metal phthalocyanine nanowire array, and an organic heterojunction nanowire array is prepared. This preparation method can achieve the directional growth and alignment of organic heterojunction nanowires, and further can achieve the in-situ large-scale construction and integration of nanowire device arrays.
Owner:SOUTH CHINA NORMAL UNIV

Synthesis method of 2-methyl-3-butyne-2-amine

The invention relates to the technical field of synthesis of fine chemical products, in particular to a synthesis method of 2-methyl-3-butyne-2-amine, which comprises the following steps: S1, mixing methyl butynol and a catalyst, dropwise adding thionyl chloride at the temperature of-10-5 DEG C for chlorination, carrying out heat preservation reaction for 1-2 hours, adding a saturated sodium chloride solution at the temperature of 5 DEG C for washing, and carrying out vacuum drying to obtain 2-methyl-3-butyne-2-amine; after liquid separation, taking out methyl butyne chloride of an organic phase for later use; and S2, adding the methyl butyne chloride obtained in the S1, a composite catalyst containing 8-hydroxyquinolinone and a polymerization inhibitor into a reaction kettle, after gas replacement is qualified, slowly introducing liquid ammonia at 0-20 DEG C for ammonolysis, keeping the pressure at 0.4-0.8 MPa, after ammonia introduction is finished, carrying out heat preservation reaction at 20-25 DEG C for 8-12 hours, after the reaction is finished, relieving the pressure, expelling ammonia by nitrogen, adding water and rectifying to obtain the 2-methyl-3-butyne-2-amine. According to the method, black waste acid in the methyl butynol chlorination process can be reduced, the increasingly serious chemical pollution problem is solved, meanwhile, silver noble metal catalyst substitutes in the ammonolysis process are developed, and the production cost is reduced.
Owner:CHENGWU CHENHUI ENVIRONMENTAL PROTECTION TECH CO LTD

Highly active 8-hydroxyquinoline rhodium complex in vitro and in vivo, and synthesis method and application thereof

PendingCN122444791ADimerCancer cell
The application discloses a high-activity 8-hydroxyquinoline rhodium complex in vivo and in vitro and a synthesis method and application thereof. The 5,7-dichloro-8-hydroxy-2-methylquinoline, dichloro (pentamethylcyclopentadienyl) rhodium (III) dimer, methanol, dimethyl sulfoxide and triethylamine are taken, and under a closed condition, the reaction is carried out at 80 DEG C for 3 days; after being cooled to 37 DEG C, filtration and drying are carried out, and the 5-chloro-8-hydroxyquinoline rhodium complex is obtained. The 5-chloro-8-hydroxyquinoline rhodium complex has obvious inhibiting effect on SK-OV-3 and SK-OV-3 / DDP cancer cells, shows superior antitumor activity, and has small toxicity to normal HL-7702 cells; the 5-chloro-8-hydroxyquinoline rhodium complex has potential medicinal value and is expected to be used for preparation of various antitumor drugs.
Owner:YULIN NORMAL UNIVERSITY

A Fe-doped graphite carbon nitride material with N defects and its preparation method and application

This invention discloses an Fe-doped graphitic carbon nitride material with nitrogen defects, its preparation method, and application. Iron nitrate nonahydrate and 8-hydroxyquinoline are heated in a water bath, and after adjusting the pH, an inky iron ligand is precipitated. The iron ligand is then mixed with melamine and calcined in air to obtain a gray-black powder material, CN-Q-Fe. This material has great potential for treating antibiotic contamination in aquatic environments, and exhibits excellent photocatalytic degradation of tetracycline antibiotics.
Owner:HENAN NORMAL UNIV

Application of 8-hydroxyquinoline in prevention and treatment of cyanobacterial bloom

The invention discloses application of 8-hydroxyquinoline in prevention and treatment of cyanobacterial bloom, and belongs to the technical field of environmental protection. The method comprises the following steps: 1) dissolving 8-hydroxyquinoline in dimethyl sulfoxide to prepare a solution with the concentration of 0.8-1mM; and 2) adding the 8-hydroxyquinoline solution prepared in the step 1) into a water body with blue-green algae outbreak according to a volume ratio of 0.1% (final concentration of 0.8-1 [mu] M), wherein the algae are subjected to mass death. 8-hydroxyquinoline has a remarkable killing effect on water-blooming cyanobacteria, and the removal rate of 0.9 mu M of 8-hydroxyquinoline on severe cyanobacterial blooms (the algae density is about 5 * 10 < 8 > cells / L) reaches 100%. 8-hydroxyquinoline has a destructive effect on a photosynthetic system of blue-green algae.
Owner:GUANGZHOU INST OF ENERGY CONVERSION CHINESE ACAD OF SCI

Preparation method of environment-friendly adhesion agent for aluminum alloy

The application relates to the technical field of adhesion agents, and discloses a preparation method of an environment-friendly adhesion agent for aluminum alloy, which comprises the following steps: adding water, potassium hydroxide, sodium chloride, sodium gluconate, anhydrous tripotassium phosphate, polyether DF-20, 8-hydroxyquinolyl polycarboxylic acid adhesion agent, sulfosuccinate and sodium isooctyl alcohol sulfate into a reaction kettle and stirring uniformly to obtain the environment-friendly adhesion agent for aluminum alloy. The 8-hydroxyquinolyl group contained in the 8-hydroxyquinolyl polycarboxylic acid adhesion agent can interact with the surface of the aluminum alloy or the tinplate through coordination, and meanwhile, the carboxyl contained in the polycarboxylic acid adhesion agent can interact with the carboxyl and other groups in the water-based acrylic resin emulsion through hydrogen bonding, so that the polycarboxylic acid adhesion agent plays a bridging role between the aluminum alloy and the acrylic resin paint film, the adhesion and the bonding performance between the acrylic resin paint film and the base material are enhanced, and better adhesion grade and greater T-peeling strength are achieved.
Owner:JIANGMEN RONGSHENG ENVIRONMENTAL PROTECTION MATERIAL TECH CO LTD

Fresh cut flower preservative as well as preparation method and application thereof

The invention discloses a fresh cut flower preservative and a preparation method and application thereof.Auricularia auricula polysaccharide and 8-hydroxyquinoline are adopted as main components for preservation, the balance is water to prepare a mixed aqueous solution, and bacterial nanocellulose (BNC) produced by protein waste liquid is adopted as a medium of the aqueous solution; and after water absorption saturation, obtaining the functional fresh-keeping material for the fresh cut flowers. The bacterial nano cellulose is biodegradable and non-toxic, and the fresh cut flower preservation gel prepared by the method is uniform and stable, is a semi-solid, is not easy to flow, and is easy to subpackage, transport and use. Compared with water-retaining cotton and flower mud, the water-retaining agent is longer in water-retaining time and easier to decompose, and the loss of an aqueous solution is reduced. The fresh-keeping period of the fresh cut flowers can be prolonged after the roots of the fresh cut flowers are placed in the packaging bag for fresh-keeping and sealing, and the packaging bag can be used for long-distance transportation of the fresh cut flowers and water retention of bouquets in flower stores.
Owner:LUDONG UNIVERSITY +1

Preparation method and application of bimodal linear polyethylene chromium carbene catalyst

The application discloses a preparation method and application of a bimodal linear polyethylene chromium carbene catalyst, and belongs to the technical field of chemical synthesis. The preparation method comprises the following steps: 1-nitro-2-aromatic sulfide benzene is prepared by taking 1-fluoro-2-nitrobenzene, aromatic mercaptan and potassium tert-butanolate as raw materials; 1-amino-2-aromatic sulfide benzene is prepared by taking 1-nitro-2-aromatic sulfide benzene and hydrazine hydrate as raw materials; 8-hydroxyimidazol[1,5-alpha] quinolinium salt is prepared by taking 1-amino-2-aromatic sulfide benzene, 8-hydroxyquinoline-2-methyl formaldehyde, formaldehyde solution and hydrogen chloride-1,4-dioxane solution as raw materials; and finally, the reaction is carried out by taking 8-hydroxyimidazol[1,5-alpha] quinolinium salt, silver trifluoromethanesulfonate, sodium bis(trimethylsilyl) amide and chromium trichloride as raw materials to obtain the bimodal linear polyethylene chromium carbene catalyst. According to the preparation method, the catalyst is effectively prevented from being poisoned, the catalytic activity of the catalyst is improved, and the catalyst has good thermal stability.
Owner:NORTHWEST UNIV

Efficient synthesis method of brexpiprazole

The invention discloses an efficient synthesis method of brexpiprazole, which comprises the following steps: taking 4-bromo-benzothiophene and N-Boc-piperazine as initial raw materials, under the protection of nitrogen, carrying out reaction by using a supported catalyst to prepare 4-Boc piperazine benzothiophene, and then carrying out acidolysis to obtain 4-piperazine benzothiophene hydrochloride; the method comprises the following steps: reacting 3, 4-dihydro-7-hydroxy-2 (1H) quinolinone with 1-bromo-4-chloro-butane to generate 3, 4-dihydro-7-(4-chlorobutoxy)-2 (1H)-quinolinone, and then converting the 3, 4-dihydro-7-(4-chlorobutoxy)-2 (1H)-quinolinone into 7-(4-chlorobutoxy)-2 (1H)-quinolinone; then condensing with 4-piperazine benzothiophene hydrochloride to obtain a crude product of brexpiprazole; and finally, crystallizing and purifying for multiple times to obtain high-purity brexpiprazole. According to the preparation method disclosed by the invention, 4-bromo-benzothiophene and N-Boc-piperazine are taken as starting raw materials, and high-purity brexpiprazole is prepared by optimizing selection of a catalyst and conditions of each step and through an excellent purification process.
Owner:SUZHOU JINGYE MEDICINE & CHEM

A mixed matrix membrane of mofs for ion sieving and method of making

This invention belongs to the field of MOF mixed matrix membrane technology, and discloses a MOF mixed matrix membrane for ion sieving and its preparation method. The preparation method includes dissolving an organic ligand and a metal source in an organic compound, ultrasonically treating it to obtain a precursor solution, subjecting the precursor solution to a hydrothermal reaction to obtain a first intermediate product, washing and vacuum drying the first intermediate product to obtain MOF-808 powder; dissolving 8-hydroxyquinoline in anhydrous ethanol, adding the MOF-808 powder, and sealing and stirring to obtain 8-Hq@MOF-808 powder; filtering the 8-Hq@MOF-808 powder onto a substrate, spin-coating an epoxy resin solution onto the substrate containing the 8-Hq@MOF-808 powder, and drying at room temperature to obtain the MOF mixed matrix membrane. The phenolic hydroxyl oxygen atom and pyridine ring nitrogen atom of 8-hydroxyquinoline act as bidentate ligands, forming a stable five-membered chelate ring with metal ions, exhibiting high coordination efficiency.
Owner:CHANGAN UNIV

Preparation method of copper sheet corrosion inhibitor for gasoline and diesel components produced as by-products from waste lubricating oil hydrogenation

The present invention discloses a method for preparing a copper sheet corrosion inhibitor for gasoline and diesel components produced as byproducts from the hydrogenation of waste lubricating oils, belonging to the technical field of petroleum product corrosion inhibition. The method comprises preparing a saturated isooctane / n-hexadecane solution of tetrazole; preparing an n-octane / n-hexadecane solution of 8-hydroxyquinoline or imidazole; mixing dropwise, adjusting the pH, and heating in a water bath; adding organic cerium, cooling, and aging the solution. The copper sheet corrosion inhibitor for gasoline and diesel components produced as byproducts from the hydrogenation of waste lubricating oils prepared using this method can significantly reduce the corrosion level of the copper sheet produced as a byproduct from the hydrogenation of waste lubricating oils, even at a very low dosage, thereby achieving the technical purpose of inhibiting copper sheet corrosion.
Owner:WUHAN KELIN FINE CHEM

Luminescent ZIF-8 material as well as preparation method and application thereof

The invention belongs to the field of material science and court science, and discloses a luminescent ZIF-8 material and a preparation method and application thereof. The invention relates to a novel luminescent ZIF-8 material, which is a luminescent material prepared by taking ZIF-8 and 8-hydroxyquinoline as raw materials, taking NaCl as a dispersion medium and modifying 8-HQ on the surface of the ZIF-8 through a solid-phase grinding method. The invention also discloses application of the luminescent ZIF-8 material in preparation of a latent fingerprint development agent or application in latent fingerprint development. The FZIF-8 can be used for latent fingerprint display, primary and secondary structure information can be clearly observed through naked eyes without other observation tools, and distribution of sweat pores in a tertiary structure can even be observed after a local image is further amplified through a microscope. The FZIF-8 shows good sensitivity and selectivity in the detection of the LFPs, and has relatively low background interference.
Owner:JIANGSU INST OF FOOD & DRUG SUPERVISION & INSPECTION

Aluminum profile powder coating and preparation method thereof

The application discloses an aluminum profile spraying powder coating and a preparation method thereof, and belongs to the technical field of paint. The application introduces modified resin, so that the coating has excellent weather resistance, and adds specific proportion of proto-catechuic acid, 2-(4-thiazolyl) benzimidazole and 8-hydroxyquinoline as an antibacterial agent, and chemically bonds the antibacterial agent to the resin base material, so that efficient, long-lasting and broad-spectrum antibacterial effect is realized, and more significant antibacterial purpose is realized, and the problems of easy migration and easy failure of the surface spraying antibacterial agent are effectively solved. The application optimizes the overall formula, and the components interact with each other, so that the coating has excellent surface flatness and apparent quality, and the defects of pinholes and orange peel commonly existing in traditional coatings are avoided; the overall antibacterial and long-lasting antibacterial properties are significant, and the application is particularly suitable for buildings, medical treatment and household aluminum profiles with high sanitary requirements.
Owner:FOSHAN POLYTECHNIC