Quinolyl amide derivative and its prepn process and use

A quinoline and amide technology, applied in the field of 4-hydroxy-quinoline-3-amide compounds, can solve problems such as treating symptoms but not root causes
CN1847226AInactive Publication Date: 2006-10-18INST OF PHARMACOLOGY & TOXICOLOGY ACAD OF MILITARY MEDICAL SCI P L A

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF PHARMACOLOGY & TOXICOLOGY ACAD OF MILITARY MEDICAL SCI P L A
Publication Date
2006-10-18
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to quinolyl amide derivatives, their preparation process, medicine compositions and use in preparing medicines for treating and / or preventing chronic nephritis, rheumarthritis, insulin dependent diabetes mellitus, systemic lupus erythematous, multiple sclerosis and other diseases.
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Description

technical field

[0001] The present invention relates to 4-hydroxy-quinoline-3-amide compounds, their preparation methods, pharmaceutical compositions containing them and the preparation of said compounds for the treatment and / or prevention of chronic nephritis, rheumatoid arthritis, insulin-dependent diabetes mellitus, Use of drugs for diseases such as systemic lupus erythematosus and multiple sclerosis. Background technique

[0002] Chronic nephritis is a class of diseases that seriously threaten human health, often leading to renal failure and endangering the lives of patients. At present, the pathogenesis of chronic nephritis is not very clear. It is generally believed to be related to immune dysfunction and belongs to autoimmune disease. There is no specific drug for its treatment. At present, hormonal drugs (cortisone, prednisone, corticosterone, cortisol, etc.) and immunosuppressive drugs (cyclosporin A, cyclophosphyl, FK506, etc.) The above-mentioned drugs need to b...

Claims

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