Quinolyl amide derivative and its prepn process and use
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- INST OF PHARMACOLOGY & TOXICOLOGY ACAD OF MILITARY MEDICAL SCI P L A
- Publication Date
- 2006-10-18
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The present invention relates to 4-hydroxy-quinoline-3-amide compounds, their preparation methods, pharmaceutical compositions containing them and the preparation of said compounds for the treatment and / or prevention of chronic nephritis, rheumatoid arthritis, insulin-dependent diabetes mellitus, Use of drugs for diseases such as systemic lupus erythematosus and multiple sclerosis. Background technique
[0002] Chronic nephritis is a class of diseases that seriously threaten human health, often leading to renal failure and endangering the lives of patients. At present, the pathogenesis of chronic nephritis is not very clear. It is generally believed to be related to immune dysfunction and belongs to autoimmune disease. There is no specific drug for its treatment. At present, hormonal drugs (cortisone, prednisone, corticosterone, cortisol, etc.) and immunosuppressive drugs (cyclosporin A, cyclophosphyl, FK506, etc.) The above-mentioned drugs need to b...